Melina Elpi Marmarelis, MD, MSCE
Assistant Professor of Medicine (Hematology-Oncology) at the Hospital of the University of Pennsylvania
Attending Physician , Hospital of the University of Pennsylvania
Attending Physician , Penn Presbyterian Medical Center
Medical Director of Penn Medicine Mesothelioma and Pleural Program, University of Pennsylvania
PC3I Faculty, Penn Center for Cancer Care Innovation, University of Pennsylvania
Department: Medicine
Contact information
Perelman Center for Advanced Medicine
3400 Civic Center Blvd
10th Floor
Philadelphia, PA 19104
3400 Civic Center Blvd
10th Floor
Philadelphia, PA 19104
Education:
BA (Bachelors in Biochemistry and Molecular Biology )
Dartmouth College, 2007.
MD (Medicine)
Harvard Medical School , 2013.
MSCE (Clinical Epidemiology )
University of Pennsylvania , 2019.
Permanent linkBA (Bachelors in Biochemistry and Molecular Biology )
Dartmouth College, 2007.
MD (Medicine)
Harvard Medical School , 2013.
MSCE (Clinical Epidemiology )
University of Pennsylvania , 2019.
Description of Clinical Expertise
Lung cancer and mesothelioma.Description of Research Expertise
Clinical trials in lung cancer in mesothelioma.Selected Publications
William Tompkins MD, Connor B. Grady MPH, Wei-Ting Hwang PhD, Krishna Chandrasekhara, Caroline McCoach MD, Fangdi Sun MD, Geoffrey Liu MD, Devalben Patel MD, Jorge Nieva MD, Amanda Herrmann MD, Kristen Marrone MD, Vincent K. Lam MD, Vamsi Velcheti MD, Stephen V. Liu MD, Gabriela Liliana Bravo Montenegro MD, Tejas Patil MD, Jared Weiss MD, Kelsey Leigh Miller MD, William Schwartzman MD, Jonathan E. Dowell MD, Khvaramze Shaverdashvili MD, Liza Villaruz MD, Amanda Cass PharmD, Wade Iams MD, Dara Aisner MD, PhD, Charu Aggarwal MD, D. Ross Camidge MD PhD, Melina E. Marmarelis MD, Lova Sun MD : Characteristics of long-term survivors with EGFR mutant (EGFRm) metastatic non-small cell lung cancer (mNSCLC). JTO CRR March 2024.Melina E. Marmarelis, Dylan G. Scholes, Cindy M. McGrath, Salvatore F. Priore, Jacquelyn J. Roth, Michael Feldman, Jennifer J.D. Morrissette, Leslie Litzky, Charu Deshpande, Jeffrey C. Thompson, Abigail Doucette, Peter E. Gabriel, Lova Sun, Aditi P. Singh, Roger B. Cohen, Corey J. Langer, Erica L. Carpenter, Charu Aggarwal : Brief Report: Impact of reflex testing on tissue-based molecular genotyping in patients with advanced non-squamous non-small cell lung cancer. Clinical Lung Cancer March 2024.
Tejas Patil MD, Alyse Staley MS, Yunan Nie MD, Mandy Sakamoto MD, Margaret Stalker MD, James M. Jurica MD, MBA, Kenna Koehler BA, Amanda Cass PharmD, Halle Kuykendall BA, Emily Schmitt MS, Emma Filar BA, Evelina Reventaite MS, Kurt D. Davies PhD, Hala Nijmeh PhD, Mary Haag PhD, Benjamin A. Yoder PharmD, Paul A. Bunn MD, Erin L. Schenk MD, PhD, Dara L. Aisner MD, PhD, Wade T. Iams MD, Melina E. Marmarelis MD, D. Ross Camidge MD, PhD: The Efficacy and Safety of Treating Acquired MET Resistance Through Combinations of Parent and MET Tyrosine Kinase Inhibitors in Patients With Metastatic Oncogene-Driven NSCLC. JTO CRR February 2024.
Melina E. Marmarelis, Dylan Scholes, Tara L. McWilliams, Wei-Ting Hwang, John Kosteva, Michael R. Costello, Lova Sun, Aditi P. Singh, Kelsey Lau-Min, Abigail Doucette, Peter E. Gabriel, Anthony Martella, Megan Roy, Jeffrey C. Thompson, Roger B. Cohen, David W. Dougherty, Lawrence N. Shulman, Corey J. Langer, Erica L. Carpenter, Charu Aggarwal : Prospective Trial of an EMR-based Nudge to Increase Molecular Genotyping in Newly Diagnosed Metastatic Non-squamous NSCLC. IASCLC WCLC 2023, Singapore September 2023 Notes: "Poster Presentation"
Se-Hoon Lee, Byoung Chul Cho, Alexander I. Spira, Sai-Hong Ignatius Ou, Saiama N. Waqar, Sujay Shah, Leonardo Trani, Pei-Ling Chu, Meena Thayu, Roland E. Knoblauch, Joshua M. Bauml, Melina E. Marmarelis : Amivantamab, Lazertinib Plus Platinum-based Chemotherapy in Post-TKI EGFR-mutated Advanced NSCLC: Updated Results from CHRYSALIS-2. IASLC World Lung conference, Singapore. September 2023 Notes: "Oral presentation"
Nikhil Yegya-Raman, Abigail T. Berman, Christine A. Ciunci, Cole Friedes, Eva Berlin, Michelle Iocolano, Xingmei Wang, Ching Lai, William P. Levin, Keith A. Cengel, Shannon E. O'Reilly, Roger B. Cohen, Charu Aggarwal, Melina E. Marmarelis, Aditi P. Singh, Lova Sun, Jeffrey D. Bradley, John P. Plastaras, Charles B. Simone II MD, Corey J. Langer, Steven J. Feigenberg: Phase II trial of consolidation pembrolizumab after proton reirradiation for thoracic recurrences of non-small cell lung cancer: Pembro after PBT ReRT for NSCLC. International Journal of Radiation Oncology*Biology*Physics Page: S0360-3016(23)07846-X. August 2023.
Nikhil Yegya-Raman, Cole Friedes, Lova Sun, Michelle Iocolano, Kristine N. Kim, Abigail Doucette, Roger B. Cohen, Kyle W. Robinson, William P. Levin, Keith A. Cengel, Brian Lally, Manuj Agarwal, Christopher A. D'Avella, Melina E. Marmarelis, John A. Kosteva, Aditi P. Singh, Christine A. Ciunci, Charu Aggarwal, Abigail T. Berman, Corey J. Langer, Steven J. Feigenberg: Utilization and factors precluding receipt of checkpoint inhibitor consolidation for stage III NSCLC in a large U.S. academic health system. Clinical Lung Cancer 24(5): 474-482, July 2023.
Charu Aggarwal, Melina E Marmarelis, Wei-Ting Hwang, Dylan G Scholes, Tara L McWilliams, Aditi P Singh, Lova Sun, John Kosteva, Michael R Costello, Roger B Cohen, Corey J Langer, Abigail Doucette, Peter N Gabriel, Lawrence N Shulman, Katharine A Rendle, Jeffrey C Thompson, Justin E Bekelman, Erica L Carpenter: Association between availability of molecular genotyping results and overall survival in patients with advanced non-squamous non-small cell lung cancer. JCO Precision Oncology Page: e2300191, July 2023.
P. Bou-Samra, A. Chang, F. Azari, G. Kennedy, A. Segil, E. Guo, M. Marmarelis, C. Langer, S. Singhal : Epidemiological, therapeutic, and survival trends in malignant pleural mesothelioma: A review of the National Cancer Database. Cancer Medicine 12(11): 12208-12220. June 2023.
L. Sun, M. Marmarelis, C. Aggarwal: Re-Evaluating Real-World Evidence in RET Fusion-Positive NSCLC: Are Randomized Clinical Trials Needed? Journal of Thoracic Oncology 18(5): 549-551, May 2023.