Melina Elpi Marmarelis, MD, MSCE

faculty photo
Assistant Professor of Medicine (Hematology-Oncology) at the Hospital of the University of Pennsylvania
Attending Physician , Hospital of the University of Pennsylvania
Attending Physician , Penn Presbyterian Medical Center
Medical Director of Penn Medicine Mesothelioma and Pleural Program, University of Pennsylvania
PC3I Faculty, Penn Center for Cancer Care Innovation, University of Pennsylvania
Department: Medicine

Contact information
Perelman Center for Advanced Medicine
3400 Civic Center Blvd
10th Floor
Philadelphia, PA 19104
Education:
BA (Bachelors in Biochemistry and Molecular Biology )
Dartmouth College, 2007.
MD (Medicine)
Harvard Medical School , 2013.
MSCE (Clinical Epidemiology )
University of Pennsylvania , 2019.
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Description of Clinical Expertise

Lung cancer and mesothelioma.

Description of Research Expertise

Clinical trials in lung cancer in mesothelioma.

Selected Publications

Marmarelis ME, Scholes DG … Aggarwal C. : Electronic Medical Record-Based Nudge Intervention to Increase Comprehensive Molecular Genotyping in Patients with Metastatic Non-Small Cell Lung Cancer: Results from a Prospective Clinical Trial. Journal of Clinical Oncology, Oncology Practice July 2024.

Natasha B. Leighl, Hiroaki Akamatsu, Sun Min Lim, Ying Cheng, Anna Rachel Minchom, Melina Elpi Marmarelis, Rachel E. Sanborn, James Chih-Hsin Yang, Baogang Liu, Tom John, Bartomeu Massuti, Alexander I. Spira, John Xie, Debropriya Ghosh, Ali Alhadab, Remy B Verheijen, Mohamed Gamil, Joshua Michael Bauml, Mahadi Baig, Antonio Passaro: Subcutaneous amivantamab vs intravenous amivantamab, both in combination with lazertinib, in refractory EGFR-mutated, advanced non-small cell lung cancer (NSCLC): Primary results, including overall survival (OS), from the global, phase 3, randomized controlled PALOMA-3 trial. ASCO 2024, oral presentation June 2024 Notes: Steering Committee Member.

Byoung Chul Cho, Yongsheng Wang, Enriqueta Felip, Jiuwei Cui, Alexander I. Spira, Joel W. Neal, Christina Baik, Melina Elpi Marmarelis, Eiki Ichihara, Jong-Seok Lee, Se-Hoon Lee, James Chih-Hsin Yang, Sebastian Yves Friedrich Michels, Zacharias Anastasiou, Joshua C Curtin, Xuesong Lyu, Isabelle LECONTE, Leonardo Trani, Mahadi Baig, Pascale Tomasini: Amivantamab plus lazertinib in atypical EGFR-mutated advanced non-small cell lung cancer (NSCLC): Results from CHRYSALIS-2. ASCO 2024 mini oral abstract June 2024.

Adam Barsouk, Omar Elghawy, Alec Heidaul, Connie Yu, David Yang, Lucy Wang, Martin Kurian, Keshav Boel, Lynn Rushkin, Anna Huang, Teja Voruganti, Lova Sun, Aditi Singh, Roger B. Cohen, Charu Aggarwal, Melina Marmarelis, Corey Langer: Real-world Outcomes of Osimertinib (Osi) vs Afatinib or Erlotinib in Patients (Pts) with Classical vs Atypical EGFR-mutated Metastatic Non-small Cell Lung Cancer (mNSCLC). ASCOC 2024, poster June 2024.

Leighl NB, Akamutsu H, Lim SM, Cheng Y, Minchom AR, Marmarelis ME, Sanborn RE… Bauml JM, Baig M, Passaro A.: Subcutaneous versus Intravenous Amivantamab, both in Combination with Lazertinib, in Refractory EGFR-mutated NSCLC: Primary Results from the Phase 3 PALOMA-3 Study. Journal of Clinical Oncology June 2024.

Omar Elghawy, Adam Barsouk, Jonathan Sussman, Christopher D'Avella, Aditi Singh, Christine Ciunci, Kyle Robinson, John Kosteva, Corey Langer, Roger Cohen, Charu Aggwarwal, Melina Marmarelis, Lova Sun: Immune-Related Adverse Events (IRAEs) After 2 years in Patients with Advanced Non-Small Cell Lung Cancer (NSCLC) Receiving Extended Immune Checkpoint Inhibitor (ICI) Therapy. ASCO 2024, poster June 2024.

William Tompkins MD, Connor B. Grady MPH, Wei-Ting Hwang PhD, Krishna Chandrasekhara, Caroline McCoach MD, Fangdi Sun MD, Geoffrey Liu MD, Devalben Patel MD, Jorge Nieva MD, Amanda Herrmann MD, Kristen Marrone MD, Vincent K. Lam MD, Vamsi Velcheti MD, Stephen V. Liu MD, Gabriela Liliana Bravo Montenegro MD, Tejas Patil MD, Jared Weiss MD, Kelsey Leigh Miller MD, William Schwartzman MD, Jonathan E. Dowell MD, Khvaramze Shaverdashvili MD, Liza Villaruz MD, Amanda Cass PharmD, Wade Iams MD, Dara Aisner MD, PhD, Charu Aggarwal MD, D. Ross Camidge MD PhD, Melina E. Marmarelis MD, Lova Sun MD : Characteristics of long-term survivors with EGFR mutant (EGFRm) metastatic non-small cell lung cancer (mNSCLC). JTO CRR March 2024.

Melina E. Marmarelis, Dylan G. Scholes, Cindy M. McGrath, Salvatore F. Priore, Jacquelyn J. Roth, Michael Feldman, Jennifer J.D. Morrissette, Leslie Litzky, Charu Deshpande, Jeffrey C. Thompson, Abigail Doucette, Peter E. Gabriel, Lova Sun, Aditi P. Singh, Roger B. Cohen, Corey J. Langer, Erica L. Carpenter, Charu Aggarwal : Brief Report: Impact of reflex testing on tissue-based molecular genotyping in patients with advanced non-squamous non-small cell lung cancer. Clinical Lung Cancer March 2024.

Tejas Patil MD, Alyse Staley MS, Yunan Nie MD, Mandy Sakamoto MD, Margaret Stalker MD, James M. Jurica MD, MBA, Kenna Koehler BA, Amanda Cass PharmD, Halle Kuykendall BA, Emily Schmitt MS, Emma Filar BA, Evelina Reventaite MS, Kurt D. Davies PhD, Hala Nijmeh PhD, Mary Haag PhD, Benjamin A. Yoder PharmD, Paul A. Bunn MD, Erin L. Schenk MD, PhD, Dara L. Aisner MD, PhD, Wade T. Iams MD, Melina E. Marmarelis MD, D. Ross Camidge MD, PhD: The Efficacy and Safety of Treating Acquired MET Resistance Through Combinations of Parent and MET Tyrosine Kinase Inhibitors in Patients With Metastatic Oncogene-Driven NSCLC. JTO CRR February 2024.

Melina E. Marmarelis, Dylan Scholes, Tara L. McWilliams, Wei-Ting Hwang, John Kosteva, Michael R. Costello, Lova Sun, Aditi P. Singh, Kelsey Lau-Min, Abigail Doucette, Peter E. Gabriel, Anthony Martella, Megan Roy, Jeffrey C. Thompson, Roger B. Cohen, David W. Dougherty, Lawrence N. Shulman, Corey J. Langer, Erica L. Carpenter, Charu Aggarwal : Prospective Trial of an EMR-based Nudge to Increase Molecular Genotyping in Newly Diagnosed Metastatic Non-squamous NSCLC. IASCLC WCLC 2023, Singapore September 2023 Notes: "Poster Presentation"

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Last updated: 07/12/2024
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