Melina Elpi Marmarelis, MD, MSCE
Assistant Professor of Medicine (Hematology-Oncology) at the Hospital of the University of Pennsylvania
Attending Physician , Hospital of the University of Pennsylvania
Attending Physician , Penn Presbyterian Medical Center
Medical Director of Penn Medicine Mesothelioma and Pleural Program, University of Pennsylvania
PC3I Faculty, Penn Center for Cancer Care Innovation, University of Pennsylvania
Physician Lead -Airways Research Program, University of Pennsyvlania
Department: Medicine
Contact information
Perelman Center for Advanced Medicine
3400 Civic Center Blvd
10th Floor
Philadelphia, PA 19104
3400 Civic Center Blvd
10th Floor
Philadelphia, PA 19104
Education:
BA (Bachelors in Biochemistry and Molecular Biology )
Dartmouth College, 2007.
MD (Medicine)
Harvard Medical School , 2013.
MSCE (Clinical Epidemiology )
University of Pennsylvania , 2019.
Permanent linkBA (Bachelors in Biochemistry and Molecular Biology )
Dartmouth College, 2007.
MD (Medicine)
Harvard Medical School , 2013.
MSCE (Clinical Epidemiology )
University of Pennsylvania , 2019.
Description of Clinical Expertise
Lung cancer and mesothelioma.Description of Research Expertise
Clinical trials in lung cancer in mesothelioma.Selected Publications
Adam Barsouk, Omar Elghawy, Alex Watts, Lauren Reed-Guy, William Tompkins, Krishna Chandrasekhara, Connor B. Grady, Wade Iams, Fangdi Sun, Geoffrey Liu, Devalben Patel, Jorge J. Nieva, Kristen A. Marrone, Vamsidhar Velcheti , Stephen V. Liu, Tejas Patil, Jared Weiss, William Schwartzman, Liza C Villaruz, Amanda Hermann, Melina E. Marmarelis: Osimertinib vs. Afatinib in 1L therapy of atypical EGFR-mutated metastatic non-small cell lung cancer (mNSCLC): A multi-institution, real-world survival analysis. Lung Cancer 203, May 2025.Lova Sun, Melina E. Marmarelis, Charu Aggarwal: Oncology Grand Rounds: Management of Patients With EGFR Exon 20-Mutant Advanced Non-Small Cell Lung Cancer. Journal of Clinical Oncology March 2025.
Margaret Stalker, Suzanne L. Walker, Emily Lebow, Emily Ling-Lin Pai, Alex Watts, Wei-Ting Hwang, Amir Banihashemi, Evan Anderson, Leonid Roshkovan, Sharyn I. Katz, Leslie Litzky, Andrew R. Haas, Sunil Singhal, Corey J. Langer, Keith Cengel, Melina E. Marmarelis: Incidence and outcomes of brain metastasis in pleural mesothelioma in the era of immunotherapy. Journal of Thoracic Oncology Clinical Research Reports March 2025.
Tejas Patila ∙ Dexiang Gaob ∙ Alexander Watsona ∙ Mandy Sakamotoa ∙ Yunan Niec ∙ Amanda Gibsond ∙ Michelle L Deand ∙ Benjamin A. Yodera ∙ Eliza Millera ∙ Margaret Stalkere ∙ Dara L. Aisnerf ∙ Paul A. Bunna ∙ Erin L. Schenka ∙ Melina E. Marmarelise ∙ Chiara Bennatig ∙ Vishal Navanid ∙ Yongchang Zhangh ∙ D. Ross Camidge: The efficacy of continuing osimertinib with platinum pemetrexed chemotherapy upon progression in patients with metastatic non-small cell lung cancer harboring sensitizing EGFR mutations. Lung Cancer 199(108040), January 2025.
Margaret Stalker, MD ∙ Connor B. Grady, MPH ∙ Alex Watts, MS ∙ Wei-Ting Hwang, PhD ∙ Krishna Chandrasekhara, MS ∙ Fangdi Sun, MD ∙ Geoffrey Liu, MD ∙ Devalben Patel, MD ∙ Jorge Nieva, MD ∙ Amanda Herrmann, MD ∙ Kristen Marrone, MD ∙ Vincent K. Lam, MD ∙ Vamsidhar Velcheti, MD ∙ Stephen V. Liu, MD ∙ Gabriela Liliana Bravo Montenegro, MD ∙ William Tompkins, MD ∙ Tejas Patil, MD ∙ Jared Weiss, MD ∙ Kelsey Leigh Miller, MD ∙ William Schwartzman, MD ∙ Jonathan E. Dowell, MD ∙ Khvaramze Shaverdashvili, MD, PhD ∙ Liza Villaruz, MD ∙ Amanda Cass, PharmD ∙ Wade Iams, MD ∙ Dara Aisner, MD, PhD ∙ Charu Aggarwal, MD, MD ∙ D. Ross Camidge, MD, PhD ∙ Lova Sun, MD ∙ Melina E. Marmarelis, MD: Changing Treatment and Metastatic Disease Patterns in Patients with EGFR Mutated NSCLC: An Academic Thoracic Medical Investigator’s Consortium Registry Analysis. JTO CRR. JTO CRR January 2025.
Elghawy O, Barsouk A, Reed-Guy L, Stalker M, Sussman J, Robinson K, Kosteva J, Singh A, Cohen RB, Langer C, Ciunci C, D'Avella C, Sun L, Marmarelis ME, Aggarwal C.: Brief Report: Osimertinib Plus Capmatinib for Patients With MET-Altered EGFR-Mutant NSCLC Following Progression on Front Line Therapy. Clin Lung Cancer Dec 2024.
Connor B. Grady, Wei-Ting Hwang, Joshua E. Reuss, Wade Iams, Amanda Cass, Geoffrey Liu, Devalben Patel, Stephen V. Liu, Gabriela Liliana Bravo Montenegro, Tejas Patil, Jorge J. Nieva, Amanda Herrmann, Kristen A. Marrone, Vincent K. Lam, William Schwartzman, Jonathan Dowell, Liza C Villaruz, Kelsey Leigh Miller, Jared Weiss, Fangdi Sun, Vamsidhar Velcheti, D. Ross Camidge, Charu Aggarwal, Lova Sun, Melina E. Marmarelis: Determining Line of Therapy from Real-World Data in Non-Small Cell Lung Cancer. Pharmacoepidemiology and Drug Safety 33(12): e70049. Dec 2024.
Benjamin Besse, MD, PhD, Koichi Goto, MD, PhD, Yongsheng Wang, MD, Se-Hoon Lee, MD, PhD, Melina E. Marmarelis, MD, Yuichiro Ohe, MD, PhD, Reyes Bernabe Caro, MD, Dong-Wan Kim, MD, PhD, Jong-Seok Lee, MD, PhD, Sophie Cousin, MD, MSc, Eiki Ichihara, MD, PhD, Yongsheng Li, MD, PhD, Paz-Ares Luis, MD, PhD, Akira Ono, MD, PhD, Rachel E. Sanborn, MD, Naohiro Watanabe, MD, Maria Jose de Miguel, MD, PhD, Carole Helissey, MD, Catherine A. Shu, MD, Alexander Spira, MD, PhD, Pascale Tomasini, MD, MSc, James Chih-Hsin Yang, MD, PhD, Yiping Zhang, MD, Enriqueta Felip, MD, PhD, Frank Griesinger, MD, PhD, Saima N. Waqar, MD, Antonio Calles, MD, Joel Neal, MD, PhD, Christina S. Baik, MD, Pasi A. Jänne, MD, PhD, S. Martin Shreeve, MD, PhD, Joshua C. Curtin, PhD, Bharvin Patel, PhD, Michael Gormley, PhD, Xuesong Lyu, PhD, Jun Chen, MD, MSc, Pei-Ling Chu, PhD, Janine Mahoney, BSN, RN, Leonardo Trani, MD, Joshua M. Bauml, MD, Meena Thayu, MD, MSCE, Roland E. Knoblauch, MD, PhD, Byoung Chul Cho, MD, PhD: Amivantamab Plus Lazertinib in Patients With EGFR-mutant Non-small Cell Lung Cancer (NSCLC) After Progression on Osimertinib and Platinum-based Chemotherapy: Results From CHRYSALIS-2 Cohort A. Journal of Thoracic Oncology December 2024 Notes: Accepted November 2024.
Stalker M, Grady CB, Watts A, Hwang WT, Chandrasekhara K, Sun F, Liu G, Patel D, Nieva J, Herrmann A, Marrone K, Lam VK, Velcheti V, Liu SV, Bravo Montenegro GL, Tompkins W, Patil T, Weiss J, Miller KL, Schwartzman W, Dowell JE, Shaverdashvili K, Villaruz L, Cass A, Iams W, Aisner D, Aggarwal C, Camidge DR, Sun L, Marmarelis ME.: Changing Treatment and Metastatic Disease Patterns in Patients with EGFR Mutated NSCLC: An Academic Thoracic Medical Investigator's Consortium Registry Analysis. JTO Clin Res Rep 6: 100765, Nov 2024.
Stalker M, Marmarelis M, Langer C, Cohen RB, Singh A, Aggarwal C, Sun L.: Outcomes Following Treatment for Progression in Patients Treated With Durvalumab Consolidation in LA-NSCLC. Clin Lung Cancer Nov 2024.