Melina Elpi Marmarelis, MD

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Assistant Professor of Medicine at the Hospital of the University of Pennsylvania
Medical Director of Penn Medicine Mesothelioma and Pleural Program, University of Pennsylvania
PC3I Affiliated Faculty, University of Pennsylvania
Department: Medicine

Contact information
Perelman Center for Advanced Medicine
3400 Civic Center Blvd
10th Floor
Philadelphia, PA 19104
BA (Bachelors in Biochemistry and Molecular Biology )
Dartmouth College, 2007.
MD (Medicine)
Harvard Medical School , 2013.
MSCE (Clinical Epidemiology )
University of Pennsylvania , 2019.
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Description of Clinical Expertise

Lung cancer and mesothelioma.

Description of Research Expertise

Clinical trials in lung cancer in mesothelioma.

Selected Publications

Marmarelis ME, Sun L, Aggarwal C: Adjuvant Atezolizumab Should Be Administered to All Patients With Programmed Death-Ligand 1 Expressing Surgically Resected Stage II to III NSCLC After Chemotherapy: In Favor. Journal of Thoracic Oncology March 2023.

Mohsin Shah, Ronac Mamtani, Melina E. Marmarelis, Sean Hennessy: Chemoimmunotherapy vs. Immunotherapy for First Line Treatment of Advanced Non–small Cell Lung Cancer With a PD-L1 Expression ≥50% or ≥90% Clinical Lung Cancer March 2023.

Melina E. Marmarelis, MD, MSCE1; Xiao Wang, MD1; Leonid Roshkovan, MD2; Connor B. Grady, MPH3; John T. Miura, MD4; Michelle S. Ginsberg, MD5; Christine A. Ciunci, MD1; Jacklynn Egger, BS6; Suzanne Walker, PhD, CRNP1; Andrea Cercek, MD7; Michael B. Foote, MD7; Leslie A. Litzky, MD8; Garrett Nash, MD, MPH9; Andrew R. Haas, MD, PhD10; Giorgos C. Karakousis, MD4; Keith A. Cengel, MD, PhD11; Sharyn I. Katz, MD2; Marjorie G. Zauderer, MD6,12; Corey J. Langer, MD1; Michael Offin, MD6,12: Clinical Outcomes Associated With Pembrolizumab Monotherapy Among Adults With Diffuse Malignant Peritoneal Mesothelioma. JAMA Network Open March 2023.

Wade T. Iams, Meridith L. Balbach, Sharon Phillips, Adrian Sacher, Christine Bestvina, Vamsidhar Velcheti, Xiao Wang, Melina E. Marmarelis, Nan Sethakorn, Ticiana Leal, Paul E. Sackstein, Chul Kim, MD Andrew Robinson, Kathan Mehta, Robert Hsu, Jorge Nieva, Tejas Patil, D. Ross Camidge: A multi-center retrospective chart review of clinical outcomes among patients with KRAS G12C mutant non-small cell lung cancer. Clinical Lung Cancer February 2023.

Byoung Chul Cho, Yongsheng Wang, Yongsheng Li, Lin Wu, Benjamin Besse, Melina E Marmarelis, Koichi Goto, Jong-Seok Lee, Se-Hoon Lee, Yiping Zhang, Joel W Neal, Joshua C Curtin, Joshua M Bauml, Janine Mahoney, Leonardo Trani, Roland E Knoblauch, Pascale Tomasini: Amivantamab in Combination with Lazertinib in Patients with Atypical Epidermal Growth Factor Receptor (EGFR) Mutations Excluding Exon 20 Insertion Mutations: Initial Results from CHRYSALIS-2  ESMO Asia, oral presentation December 2022.

Wang X, Katz S, Miura J, Karakousis G, Roshkovan L, Walker S, McNulty S, Ciunci C, Cengel K, Langer CJ, Marmarelis ME: A single-center retrospective cohort study of perioperative systemic chemotherapy in diffuse malignant peritoneal mesothelioma. PLOS ONE October 2022.

X. Wang; Michael Offin; L. Roshkovan; J. T. Miura; M. Ginsberg; C. A. Ciunci; J. Egger; S. Walker; A. Cercek; L. A. Litzky; G. Nash; A. R. Haas; G. C. Karakousis; K. A. Cengel; S. I. Katz; M. Zauderer; C. J. Langer; M. E. Marmarelis: Clinical activity of pembrolizumab monotherapy in diffuse malignant peritoneal mesothelioma. ASCO Annual Meeting Poster Presentation June 2022.

Mohsin Shah,Rebecca A. Hubbard,Ronac Mamtani,Melina E. Marmarelis,Sean Hennessy: Very high PD-L1 expression as a prognostic indicator of overall survival among patients with advanced non-small cell lung cancer receiving anti-PD-(L)1 monotherapies in routine practice. Pharmacoepidemiology & Drug Safety June 2022.

Melina Marmarelis, Connor Grady, Geoffrey Liu, Devalben Patel, Stephen Liu, Gabriela Bravo Montenegro, Tejas Patil, Jorge Nieva, Amanda Herrmann, Kristen Marrone, Vincent Lam, Fangdi Sun, Jonathan Dowell, Vamsidhar Velcheti, Matthew Nguyen, Kelsey Miller, Wade Iams, Wei-Ting Hwang, D. Ross Camidge, Charu Aggarwal: Treatment Patterns and Outcomes in ALK or ROS1 altered NSCLC: An ATOMIC Registry Study ASCO 2022 Annual Meeting Poster Presentation June 2022.

Charu Aggarwal, Melina E. Marmarelis, Wei-Ting Hwang, Dylan P. Scholes, Tara L. McWilliams, Aditi P. Singh, Lova Sun, John Kosteva, Michael R. Costello, Roger B. Cohen, Corey J. Langer, Peter E. Gabriel, Lawrence N. Shulman, Jeffrey C. Thompson, Erica L. Carpenter: Association of comprehensive molecular genotyping and overall survival in patients with advanced non-squamous non-small cell lung cancer. ASCO Annual Meeting Poster Discussion June 2022.

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Last updated: 03/28/2023
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