Devan V. Mehrotra, PhD

Adjunct Professor of Biostatistics and Epidemiology
Adjunct Scholar, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania Perelman School of Medicine
Department: Biostatistics and Epidemiology
Contact information
351 North Sumneytown Pike
North Wales, PA 19454
North Wales, PA 19454
Office: 215 776 6794
Education:
BSc (Mathematis & Statistics)
St. Xaviers College, 1984.
MSc (Statistics)
University of Bombay, 1986.
PhD (Statistics)
University of Delaware, 1991.
Permanent linkBSc (Mathematis & Statistics)
St. Xaviers College, 1984.
MSc (Statistics)
University of Bombay, 1986.
PhD (Statistics)
University of Delaware, 1991.
Description of Clinical Expertise
Clinical Trials, Pharmaceutical R&D, Vaccines, Precision MedicineDescription of Other Expertise
Organizational LeadershipDescription of Research Expertise
Biostatistics: Survival Analysis, Risk Stratification, Missing Data, Covariate-Adjustment, Composite Endpoints, Multiple TestingSelected Publications
Liu F, Zhao Q, Rodgers AJ, Mehrotra DV.: Calculation of Phase 2 dose-finding study sample size for reliable Phase 3 dose selection. Pharm Stat Aug 2023.Zhai S, Guo B, Wu B, Mehrotra DV, Shen J.: Integrating multiple traits for improving polygenic risk prediction in disease and pharmacogenomics GWAS. Brief Bioinform 24: bbad181, Jul 2023.
Luo L, Mehrotra DV, Shen J, Tang ZZ.: Multi-trait analysis of gene-by-environment interactions in large-scale genetic studies. Biostatistics Mar 2023.
Zhang H, Mehrotra DV, Shen J.: AWOT and CWOT for genotype and genotype-by-treatment interaction joint analysis in pharmacogenetics GWAS. Bioinformatics 39: btac834, Jan 2023.
Zhong W, Chhibber A, Luo L, Mehrotra DV, Shen J.: A fast and powerful linear mixed model approach for genotype-environment interaction tests in large-scale GWAS. Brief Bioinform 24: bbac547, Jan 2023.
Xie Y, Zhai S, Jiang W, Zhao H, Mehrotra DV, Shen J.: Statistical assessment of biomarker replicability using MAJAR method. Stat Methods Med Res 2023.
Zhai S, Zhang H, Mehrotra DV, Shen J.: Pharmacogenomics polygenic risk score for drug response prediction using PRS-PGx methods. Nat Commun 13: 5278, Sep 2022.
Cai H, Lu W, Marceau West R, Mehrotra DV, Huang L.: CAPITAL: Optimal subgroup identification via constrained policy tree search. Stat Med 41: 4227-4244, Sep 2022.
Zhang H, Chhibber A, Shaw PM, Mehrotra DV, Shen J.: A statistical perspective on baseline adjustment in pharmacogenomic genome-wide association studies of quantitative change. NPJ Genom Med 7: 33, Jun 2022.
Ko S, German CA, Jensen A, Shen J, Wang A, Mehrotra DV, Sun YV, Sinsheimer JS, Zhou H, Zhou JJ.: GWAS of longitudinal trajectories at biobank scale. Am J Hum Genet 109: 433-445, Mar 2022.