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Maria A. Oquendo, M.D., Ph.D.
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Ruth Meltzer Professor of Psychiatry
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Chairman of Psychiatry, Perelman School of Medicine, University of Pennsylvania
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Psychiatrist-in-Chief , University of Pennsylvania Health System
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Department: Psychiatry
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Contact information
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3535 Market Street
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Philadelphia, PA 19104
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2c Suite 200
Philadelphia, PA 19104
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Education:
21 7 BS c
3a Tufts University, summa cum laude, 1980.
21 7 MD c
50 Columbia University, College of Physicians and Surgeons, 1984.
21 8 PhD c
48 Universidad Autonoma de Madrid, summa cum laude, 2010.
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Permanent link21 7 BS c
3a Tufts University, summa cum laude, 1980.
21 7 MD c
50 Columbia University, College of Physicians and Surgeons, 1984.
21 8 PhD c
48 Universidad Autonoma de Madrid, summa cum laude, 2010.
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198 Donnelly, HK; Brown, GK; Green, KL; Vurgun, U; Hwang, S; Schriver, E; Steinberg, M; Reilly, ME; Mehta, H; Labouliere, C; Oquendo, MA; Mandell, D; Mowery, DL : Automated Safety Plan Scoring in Outpatient Mental Health Settings Using Large Language Models: Exploratory Study. JMIR Mental Health 2026 Notes: https://doi.org/10.2196/79010.
1b2 Smith, A; Graña, J; Bhugra, D; Oquendo, MA; Buadze, A; Ventriglio, A; Liebrenz, M : It's a Complicated Issue: Exploring Perspectives on Reddit from 2016 to 2024 about the American Psychiatric Association's Goldwater Rule and the Ethics of Public-professional Mental Health Commentary. BMC Medical Ethics 2026 Notes: https://doi.org/10.1186/s12910-026-01447-x
1b9 Donnelly, HK; Mandell, D; Hwang, S; Schriver, E; Vurgun, U; Neill, G; Patel, E; Reilly, ME; Steinberg, M; Calloway, A; Gallop, R; Oquendo, MA; Brown, GK; Mowery, DL : Data Science Education for Residents, Researchers, and Students in Psychiatry and Psychology: Program Development and Evaluation Study. JMIR Medical Education 2026 Notes: https://doi.org/10.2196/75125.
1ed Kas, MJH; Do, KQ; Sand, MS; Kozak, R; Tunbridge, EM; Oquendo, MA; Tamminga, C; Koutsouleris, N; Knudsen, GM; Penninx, BW; Padberg, FJ; Drevets, WC; Falkai, P; Buhl, DL; Reif, A: Biomarker innovations in precision psychiatry diagnostics and treatment strategies. European Neuropsychopharmacology : The Journal of the European College of Neuropsychopharmacology 2026 Notes: https://doi.org/10.1016/j.euroneuro.2026.112762.
1a8 Ongur, D; Abi Dargham, A; Clarke, D; Compton, W; Cuthbert, B; Fung, K; Gogtay, N; Kas, M; Kumar, A; Malaspina, D; O’Keefe, V; Oquendo, MA; Wainberg, M; Yonkers, K; Yousif, L; Alpert, J : The Future of DSM: A Report from the Structure and Dimensions Committee. The American Journal of Psychiatry 2026 Notes: https://doi.org/10.1176/appi.ajp.20250876
1b3 Oquendo, MA; Abi Dargham, A; Alpert, J; Benton, T; Clarke, D; Compton, W; Drexler, K; Fung, K; Kas, M; Malaspina, D; O’Keefe, V; Ongur, D; Wainberg, M; Yonkers, K; Yousif, L; Gogtay, N: Initial Strategy For the Future of The Diagnostic and Statistical Manual (DSM). The American Journal of Psychiatry 2026 Notes: DOI: https://doi.org/10.1176/appi.ajp.20250878.
1db Cuthbert, B; Ajilore, O; Alpert, J; Clarke, D; Compton, W; Drexler, K; Fung, K; Gogtay, N; Kas, M; Kumar, A; Malaspina, D; O’Keefe, V; Ongur, D; Tamminga, C; Wainberg, M; Yonkers, K; Yousif, L; Abi Dargham, A; Oquendo, MA : The Role of Candidate Biomarkers and Biological Factors in the Diagnostic and Statistical Model. The American Journal of Psychiatry 2026 Notes: DOI: 10.1176/appi.ajp.20250877.
185 Zelazny, J; Porta, G; Mann, JJ; Keilp, J; Oquendo, MA; Burke, A; Brent, D; Melhem, N : Proximal Risk of Suicide Related Behavior (SRB) in Black Youth with a Parental History of Mood Disorder. Journal of the American Psychiatric Nurses Association 2026 Notes: DOI: 10.1177/10783903261424854/ ID: JAPNA-2025-OR-229.R1.
11a Barzilay, R; Sudol, K; Daskalakis, NP; Boldrini, M; Oquendo, MA : Pursuing the Elusive Biosignature for Suicide: A Decennial Update. Molecular Psychiatry 2026 Notes: https://doi.org/10.1038/s41380-026-03507-5
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Selected Publications
153 Wadden, TA; Oquendo, MA; Kushner, RF; Cao, D; Karanikas, CA; Kechter, A; Murphy, MA : Psychiatric Safety of Tirzepatide in People With Obesity and No Known Major Psychopathology: A Post Hoc Analysis of SURMOUNT. Obesity 2026 Notes: https://doi.org/10.1002/oby.70122.198 Donnelly, HK; Brown, GK; Green, KL; Vurgun, U; Hwang, S; Schriver, E; Steinberg, M; Reilly, ME; Mehta, H; Labouliere, C; Oquendo, MA; Mandell, D; Mowery, DL : Automated Safety Plan Scoring in Outpatient Mental Health Settings Using Large Language Models: Exploratory Study. JMIR Mental Health 2026 Notes: https://doi.org/10.2196/79010.
1b2 Smith, A; Graña, J; Bhugra, D; Oquendo, MA; Buadze, A; Ventriglio, A; Liebrenz, M : It's a Complicated Issue: Exploring Perspectives on Reddit from 2016 to 2024 about the American Psychiatric Association's Goldwater Rule and the Ethics of Public-professional Mental Health Commentary. BMC Medical Ethics 2026 Notes: https://doi.org/10.1186/s12910-026-01447-x
1b9 Donnelly, HK; Mandell, D; Hwang, S; Schriver, E; Vurgun, U; Neill, G; Patel, E; Reilly, ME; Steinberg, M; Calloway, A; Gallop, R; Oquendo, MA; Brown, GK; Mowery, DL : Data Science Education for Residents, Researchers, and Students in Psychiatry and Psychology: Program Development and Evaluation Study. JMIR Medical Education 2026 Notes: https://doi.org/10.2196/75125.
1ed Kas, MJH; Do, KQ; Sand, MS; Kozak, R; Tunbridge, EM; Oquendo, MA; Tamminga, C; Koutsouleris, N; Knudsen, GM; Penninx, BW; Padberg, FJ; Drevets, WC; Falkai, P; Buhl, DL; Reif, A: Biomarker innovations in precision psychiatry diagnostics and treatment strategies. European Neuropsychopharmacology : The Journal of the European College of Neuropsychopharmacology 2026 Notes: https://doi.org/10.1016/j.euroneuro.2026.112762.
1a8 Ongur, D; Abi Dargham, A; Clarke, D; Compton, W; Cuthbert, B; Fung, K; Gogtay, N; Kas, M; Kumar, A; Malaspina, D; O’Keefe, V; Oquendo, MA; Wainberg, M; Yonkers, K; Yousif, L; Alpert, J : The Future of DSM: A Report from the Structure and Dimensions Committee. The American Journal of Psychiatry 2026 Notes: https://doi.org/10.1176/appi.ajp.20250876
1b3 Oquendo, MA; Abi Dargham, A; Alpert, J; Benton, T; Clarke, D; Compton, W; Drexler, K; Fung, K; Kas, M; Malaspina, D; O’Keefe, V; Ongur, D; Wainberg, M; Yonkers, K; Yousif, L; Gogtay, N: Initial Strategy For the Future of The Diagnostic and Statistical Manual (DSM). The American Journal of Psychiatry 2026 Notes: DOI: https://doi.org/10.1176/appi.ajp.20250878.
1db Cuthbert, B; Ajilore, O; Alpert, J; Clarke, D; Compton, W; Drexler, K; Fung, K; Gogtay, N; Kas, M; Kumar, A; Malaspina, D; O’Keefe, V; Ongur, D; Tamminga, C; Wainberg, M; Yonkers, K; Yousif, L; Abi Dargham, A; Oquendo, MA : The Role of Candidate Biomarkers and Biological Factors in the Diagnostic and Statistical Model. The American Journal of Psychiatry 2026 Notes: DOI: 10.1176/appi.ajp.20250877.
185 Zelazny, J; Porta, G; Mann, JJ; Keilp, J; Oquendo, MA; Burke, A; Brent, D; Melhem, N : Proximal Risk of Suicide Related Behavior (SRB) in Black Youth with a Parental History of Mood Disorder. Journal of the American Psychiatric Nurses Association 2026 Notes: DOI: 10.1177/10783903261424854/ ID: JAPNA-2025-OR-229.R1.
11a Barzilay, R; Sudol, K; Daskalakis, NP; Boldrini, M; Oquendo, MA : Pursuing the Elusive Biosignature for Suicide: A Decennial Update. Molecular Psychiatry 2026 Notes: https://doi.org/10.1038/s41380-026-03507-5
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