Marielle Scherrer-Crosbie, MD, PhD
Professor of Medicine (Cardiovascular Medicine) at the Hospital of the University of Pennsylvania
Attending Physician, Hospital of the University of Pennsylvania
Director Echocardiography, Hospital of the University of Pennsylvania
Director, Echocardiography, Penn Cardiovascular Institute
Department: Medicine
Contact information
Perelman Center for Advanced Medicine
Cardiovascular Medicine Division
11th Floor - South Tower
3400 Civic Center Boulevard
Philadelphia, PA 19104
Cardiovascular Medicine Division
11th Floor - South Tower
3400 Civic Center Boulevard
Philadelphia, PA 19104
Office: 215-662-3569
Education:
D.E.A. (Cardiovascular Physiology)
Paris VI University, France, 1991.
D.E.S.C (Nuclear Medicine)
INSTN, Paris, France, 1992.
M.D. (Medicine)
Paris XII University, France, 1993.
D.U. (Echocardiography)
Paris XII University, France, 1996.
Ph.D. (Cardiovascular Physiology)
Paris XII University, France, 2003.
Permanent linkD.E.A. (Cardiovascular Physiology)
Paris VI University, France, 1991.
D.E.S.C (Nuclear Medicine)
INSTN, Paris, France, 1992.
M.D. (Medicine)
Paris XII University, France, 1993.
D.U. (Echocardiography)
Paris XII University, France, 1996.
Ph.D. (Cardiovascular Physiology)
Paris XII University, France, 2003.
Description of Research Expertise
ISCHEMIA Research Group. Initial Invasive or Conservative Strategy for Stable Coronary Artery Disease. N Engl J Med. 2020 Apr 9;382(15):1395-1407. doi: 10.1056/NEJMoa1915922. Epub 2020 Mar 30.PMID: 32227755 Clinical Trial.ISCHEMIA Research Group. Health-Status Outcomes with Invasive or Conservative Care in Corionary Disease. N Engl J Med. 2020 Apr 9;382(15):1408-1419. doi: 10.1056/NEJMoa1916370. Epub 2020 Mar 30.PMID: 32227753 Clinical Trial.
Symptomatic Heart Failure in Acute Leukemia Patients Treated with Anthracyclines. JACC CardioOncol. 2019 Dec;1(2):208-217. doi: 10.1016/j.jaccao.2019.10.008. Epub 2019 Dec 17.PMID: 32905430
State of the Art: Imaging for Myocardial Viability: A Scientific Statement from the American heart Association. American Heart Association Council on Cardiovascular Radiology and Intervention and Council on Clinical Cardiology.Circ Cardiovasc Imaging. 2020 Jul;13(7):e000053. doi: 10.1161/HCI.0000000000000053. Epub 2020 Jul 13.PMID: 32833510
Cardioavscular Effects of CAR T Cell Therapy: A Retrospective Study. JACC CardioOncol. 2020 Jun;2(2):193-203. doi: 10.1016/j.jaccao.2020.04.012. Epub 2020 Jun 16.PMID: 32776016
Deficiency of bone morphogenetic protein-3b induces metabolic syndrome and increases adipogenesis. Am J Physiol Endocrinol Metab. 2020 Aug 1;319(2):E363-E375. doi: 10.1152/ajpendo.00362.2019. Epub 2020 Jun 30.PMID: 32603262
Selected Publications
Neilan TG, Quinaglia T, Onoue T, Mahmood SS, Drobni ZD, Gilman HK, Smith A, Heemelaar JC, Brahmbhatt P, Ho JS, Sama S, Svoboda J, Neuberg DS, Abramson JS, Hochberg EP, Barnes JA, Armand P, Jacobsen ED, Jacobson CA, Kim AI, Soumerai JD, Han Y, Friedman RS, Lacasce AS, Ky B, Landsburg D, Nasta S, Kwong RY, Jerosch-Herold M, Redd RA, Hua L, Januzzi JL, Asnani A, Mousavi N, Scherrer-Crosbie M. : Atorvastatin for Anthracycline-Associated Cardiac Dysfunction: The STOP-CA Randomized Clinical Trial. JAMA August 2023.Stone GW, Ali ZA, O'Brien SM, Rhodes G, Genereux P, Bangalore S, Mavromatis K, Horst J, Dressler O, Poh KK, Nath RK, Moorthy N, Witkowski A, Dwivedi SK, Bockeria O, Chen J, Smanio PEP, Picard MH, Chaitman BR, Berman DS, Shaw LJ, Boden WE, White HD, Fremes SE, Rosenberg Y, Reynolds HR, Spertus JA, Hochman JS, Maron DJ; : ISCHEMIA Research Group. Impact of Complete Revascularization in the ISCHEMIA Trial. J Am Coll Cardiol. July 2023.
Martí-Pàmies Í, Thoonen R, Morley M, Graves L, Tamez J, Caplan A, McDaid K, Yao V, Hindle A, Gerszten RE, Farrell LA, Li L, Tseng YH, Profeta G, Buys ES, Bloch DB, Scherrer-Crosbie M. : Brown Adipose Tissue and BMP3b Decrease Injury in Cardiac Ischemia-Reperfusion. Circ Res July 2023.
Titus A, Cheema HA, Shafiee A, Seighali N, Shahid A, Bhanushali KB, Kumar A, Khan SU, Khadke S, Thavendiranathan P, Hundley WG, Scherrer-Crosbie M, Nohria A, Neilan TG, Dani SS, Nasir K, Ganatra S.: Statins for Attenuating Cardiotoxicity in Patients Receiving Anthracyclines: A Systematic Review and Meta-Analysis. Curr Probl Cardiol. June 2023.
Nagueh SF, Klein AL, Scherrer-Crosbie M, Fine NM, Kirkpatrick JN, Forsha DE, Nicoara A, Mackensen GB, Tilkemeier PL, Doukky R, Cheema B, Adusumalli S, Hill JC, Tanguturi VK, Ouyang D, Bdoyan SB, Strom JB. : Vision for the Future of Quality in Echocardiographic Reporting: The American Society of Echocardiography ImageGuideEcho Registry, Current and Future States. A J Am Soc Echocardiogr. May 2023.
Parashar S, Akhter N, Paplomata E, Elgendy IY, Upadhyaya D, Scherrer-Crosbie M, Okwuosa TM, Sanghani RM, Chalas E, Lindley KJ, Dent S: Cancer Treatment-Related Cardiovascular Toxicity in Gynecologic Malignancies JACC: CardioOncology State-of-the-Art Review April 2023.
Doukas PG, Cascino GJ, Meng Z, Baldridge AS, Kang Y, Scherrer-Crosbie M, Akhter N.: External validation of a heart failure risk score in patients with acute myeloid leukemia. Leuk Lymphoma. February 2023.
Hassan MZO, Awadalla M, Tan TC, Scherrer-Crosbie M, Bakar RB, Drobni ZD, Zarif A, Gilman HK, Supraja S, Nikolaidou S, Zhang L, Zlotoff DA, Hickey SB, Patel SA, Januzzi JL, Keane F, Passeri JJ, Neilan TG, MacDonald SM, Jimenez RB.: Serial Measurement of Global Longitudinal Strain Among Women With Breast Cancer Treated With Proton Radiation Therapy: A Prospective Trial for 70 Patients. Int J Radiat Oncol Biol Phys. February 2023.
Guo Z, Valenzuela Ripoll C, Picataggi A, Rawnsley DR, Ozcan M, Chirinos JA, Chendamarai E, Girardi A, Riehl T, Evie H, Diab A, Kovacs A, Hyrc K, Ma X, Asnani A, Shewale SV, Scherrer-Crosbie M, Cowart LA, Parks JS, Zhao L, Gordon D, Ramirez-Valle F, Margulies KB, Cappola TP, Desai AA, Pedersen LN, Bergom C, Stitziel NO, Rettig MP, DiPersio JF, Hajny S, Christoffersen C, Diwan A, Javaheri A.: Apolipoprotein M Attenuates Anthracycline Cardiotoxicity and Lysosomal Injury. JACC Basic Transl Sci Jan 2023.
Malaty MM, Amarasekera AT, Li C, Scherrer-Crosbie M, Tan TC: Incidence of immune checkpoint inhibitor mediated cardiovascular toxicity: A systematic review and meta-analysis. Eur J Clin Invest 52: e13831, Dec 2022.