Marielle Scherrer-Crosbie, MD, PhD
Professor of Medicine (Cardiovascular Medicine) at the Hospital of the University of Pennsylvania
Attending Physician, Hospital of the University of Pennsylvania
Director Echocardiography, Hospital of the University of Pennsylvania
Director, Echocardiography, Penn Cardiovascular Institute
Department: Medicine
Contact information
Perelman Center for Advanced Medicine
Cardiovascular Medicine Division
11th Floor - South Tower
3400 Civic Center Boulevard
Philadelphia, PA 19104
Cardiovascular Medicine Division
11th Floor - South Tower
3400 Civic Center Boulevard
Philadelphia, PA 19104
Office: 215-662-3569
Education:
D.E.A. (Cardiovascular Physiology)
Paris VI University, France, 1991.
D.E.S.C (Nuclear Medicine)
INSTN, Paris, France, 1992.
M.D. (Medicine)
Paris XII University, France, 1993.
D.U. (Echocardiography)
Paris XII University, France, 1996.
Ph.D. (Cardiovascular Physiology)
Paris XII University, France, 2003.
Permanent linkD.E.A. (Cardiovascular Physiology)
Paris VI University, France, 1991.
D.E.S.C (Nuclear Medicine)
INSTN, Paris, France, 1992.
M.D. (Medicine)
Paris XII University, France, 1993.
D.U. (Echocardiography)
Paris XII University, France, 1996.
Ph.D. (Cardiovascular Physiology)
Paris XII University, France, 2003.
Description of Research Expertise
ISCHEMIA Research Group. Initial Invasive or Conservative Strategy for Stable Coronary Artery Disease. N Engl J Med. 2020 Apr 9;382(15):1395-1407. doi: 10.1056/NEJMoa1915922. Epub 2020 Mar 30.PMID: 32227755 Clinical Trial.ISCHEMIA Research Group. Health-Status Outcomes with Invasive or Conservative Care in Corionary Disease. N Engl J Med. 2020 Apr 9;382(15):1408-1419. doi: 10.1056/NEJMoa1916370. Epub 2020 Mar 30.PMID: 32227753 Clinical Trial.
Symptomatic Heart Failure in Acute Leukemia Patients Treated with Anthracyclines. JACC CardioOncol. 2019 Dec;1(2):208-217. doi: 10.1016/j.jaccao.2019.10.008. Epub 2019 Dec 17.PMID: 32905430
State of the Art: Imaging for Myocardial Viability: A Scientific Statement from the American heart Association. American Heart Association Council on Cardiovascular Radiology and Intervention and Council on Clinical Cardiology.Circ Cardiovasc Imaging. 2020 Jul;13(7):e000053. doi: 10.1161/HCI.0000000000000053. Epub 2020 Jul 13.PMID: 32833510
Cardioavscular Effects of CAR T Cell Therapy: A Retrospective Study. JACC CardioOncol. 2020 Jun;2(2):193-203. doi: 10.1016/j.jaccao.2020.04.012. Epub 2020 Jun 16.PMID: 32776016
Deficiency of bone morphogenetic protein-3b induces metabolic syndrome and increases adipogenesis. Am J Physiol Endocrinol Metab. 2020 Aug 1;319(2):E363-E375. doi: 10.1152/ajpendo.00362.2019. Epub 2020 Jun 30.PMID: 32603262
Selected Publications
Picard MH, Saysana K, Cyr DD, Zeng X, Scherrer-Crosbie M, Shaw LJ, Senior R, Poh KK, Bangalore S, Leipsic JA, Mancini GJ, Budoff MJ, Hague CJ, Min JK, O'Brien SM, Hochman JS, Maron DJ, Reynolds HR; ISCHEMIA Research Group.: Stress Echocardiography in Patients with Moderate or Severe Myocardial Ischemia: Insights from the ISCHEMIA Trial J Am Soc Echocardiogr. March 2025.Juhasz V, Quinaglia T, Drobni ZD, Heemelaar JC, Neuberg DS, Han Y, Ky B, Kwong RY, Januzzi JL, Asnani A, Redd RA, Mousavi N, Jerosch-Herold M, Scherrer-Crosbie M, Neilan TG.: Atorvastatin and Myocardial Extracellular Volume Expansion During Anthracycline-Based Chemotherapy JACC CardioOncol. February 2025.
Juhasz V, Quinaglia T, Drobni ZD, Heemelaar JC, Neuberg DS, Han Y, Ky B, Kwong RY, Januzzi JL, Asnani A, Redd RA, Mousavi N, Jerosch-Herold M, Scherrer-Crosbie M, Neilan TG.: Atorvastatin and Myocardial Extracellular Volume Expansion During Anthracycline-Based Chemotherapy JACC CardioOncol. February 2025.
Khattab M, Baig M, El Zarif T, Barac A, Ferencik M, Henry ML, Lopez-Mattei J, Redheuil A, Salem JE, Scherrer-Crosbie M, Yang EH, Baldassarre LA.: How to Use Imaging: Complex Cases of Atherosclerosis, Myocardial Inflammation, and Cardiomyopathy in Cardio-Oncology. Circ Cardiovasc Imaging. January 2025.
Reynolds HR, Page CB, Shaw LJ, Berman DS, Chaitman BR, Picard MH, Kwong RY, Min JK, Leipsic J, Mancini GBJ, Budoff MJ, Hague CJ, Senior R, Szwed H, Bhargava B, Celutkiene J, Gadkari M, Bainey KR, Doerr R, Ramos RB, Ong P, Naik SR, Steg PG, Goetschalckx K, Chow BJW, Scherrer-Crosbie M, Phillips L, Mark DB, Spertus JA, Alexander KP, O'Brien SM, Boden WE, Bangalore S, Stone GW, Maron DJ, Hochman JS; ISCHEMIA Research Group.: Relationship Between Severity of Ischemia and Coronary Artery Disease for Different Stress Test Modalities in the ISCHEMIA Trial. Circ Cardiovasc Interv. December 2024.
Onoue T, Matthews AH, Vakilpour A, Kang Y, Lefebvre B, Smith AM, McCurdy SR, Fradley MG, Carver J, Chittams J, Scherrer-Crosbie M.: Cardiotoxicity of venetoclax in patients with acute myeloid leukemia: comparison with anthracyclines. Cardiooncology November 2024.
Raisi-Estabragh Z, Murphy AC, Ramalingam S, Scherrer-Crosbie M, Lopez-Fernandez T, Reynolds KL, Aznar M, Lin AE, Libby P, Cordoba R, Bredsen-Masley C, Wechalekar A, Apperley J, Cheng RK, Manisty CH.: Cardiovascular Considerations Before Cancer Therapy: Gaps in Evidence and JACC: CardioOncology Expert Panel Recommendations. JACC CardioOncol. October 2024.
Kang Y, Lefebvre B, Pamies IM, Gill SI, Doucette AG, Denduluri S, Smith AM, McCurdy S, Luger S, Carver J, Scherrer-Crosbie M.: Symptomatic Heart Failure and Clonal Hematopoiesis-Related Mutations in Patients With Acute Myeloid Leukemia. Am J Cardiol July 2024.
Bhasin V, Vakilpour A, Scherrer-Crosbie M.: Statins for the Primary Prevention of Anthracycline Cardiotoxicity: A Comprehensive Review. Curr Oncol Rep July 2024.
Makhlin I, Demissei BG, D'Agostino R, Hundley WG, Baleanu-Gogonea C, Wilcox NS, Chen A, Smith AM, O'Connell NS, Januzzi JL, Lesser GJ, Scherrer-Crosbie M, Ibáñez B, Tang WHW, Ky B: Statins Do Not Significantly Affect Oxidative Nitrosative Stress Biomarkers in the PREVENT Randomized Clinical Trial. Clin Cancer Res. June 2024.