Iain Mathieson, Ph.D.

faculty photo
Assistant Professor of Genetics
Department: Genetics
Graduate Group Affiliations

Contact information
405B Clinical Research Building
415 Curie Boulevard
Philadelphia, PA 19104-6145
Office: 215-573-1835
Education:
BA (Mathematics)
Cambridge University, 2005.
MPhil (Statistical Science)
Cambridge University, 2006.
PhD (Genomic Medicine & Statistics)
Oxford University, 2013.
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Selected Publications

Mathieson Iain, Reich David: Differences in the rare variant spectrum among human populations. PLoS genetics 13(2): e1006581, Feb 2017.

Mallick Swapan, Li Heng, Lipson Mark, Mathieson Iain, Gymrek Melissa, Racimo Fernando, Zhao Mengyao, Chennagiri Niru, Nordenfelt Susanne, Tandon Arti, Skoglund Pontus, Lazaridis Iosif, Sankararaman Sriram, Fu Qiaomei, Rohland Nadin, Renaud Gabriel, Erlich Yaniv, Willems Thomas, Gallo Carla, Spence Jeffrey P, Song Yun S, Poletti Giovanni, Balloux Francois, van Driem George, de Knijff Peter, Romero Irene Gallego, Jha Aashish R, Behar Doron M, Bravi Claudio M, Capelli Cristian, Hervig Tor, Moreno-Estrada Andres, Posukh Olga L, Balanovska Elena, Balanovsky Oleg, Karachanak-Yankova Sena, Sahakyan Hovhannes, Toncheva Draga, Yepiskoposyan Levon, Tyler-Smith Chris, Xue Yali, Abdullah M Syafiq, Ruiz-Linares Andres, Beall Cynthia M, Di Rienzo Anna, Jeong Choongwon, Starikovskaya Elena B, Metspalu Ene, Parik Jüri, Villems Richard, Henn Brenna M, Hodoglugil Ugur, Mahley Robert, Sajantila Antti, Stamatoyannopoulos George, Wee Joseph T S, Khusainova Rita, Khusnutdinova Elza, Litvinov Sergey, Ayodo George, Comas David, Hammer Michael F, Kivisild Toomas, Klitz William, Winkler Cheryl A, Labuda Damian, Bamshad Michael, Jorde Lynn B, Tishkoff Sarah A, Watkins W Scott, Metspalu Mait, Dryomov Stanislav, Sukernik Rem, Singh Lalji, Thangaraj Kumarasamy, Pääbo Svante, Kelso Janet, Patterson Nick, Reich David: The Simons Genome Diversity Project: 300 genomes from 142 diverse populations. Nature 538(7624): 201-206, Oct 2016.

Fu Qiaomei, Posth Cosimo, Hajdinjak Mateja, Petr Martin, Mallick Swapan, Fernandes Daniel, Furtwängler Anja, Haak Wolfgang, Meyer Matthias, Mittnik Alissa, Nickel Birgit, Peltzer Alexander, Rohland Nadin, Slon Viviane, Talamo Sahra, Lazaridis Iosif, Lipson Mark, Mathieson Iain, Schiffels Stephan, Skoglund Pontus, Derevianko Anatoly P, Drozdov Nikolai, Slavinsky Vyacheslav, Tsybankov Alexander, Cremonesi Renata Grifoni, Mallegni Francesco, Gély Bernard, Vacca Eligio, Morales Manuel R González, Straus Lawrence G, Neugebauer-Maresch Christine, Teschler-Nicola Maria, Constantin Silviu, Moldovan Oana Teodora, Benazzi Stefano, Peresani Marco, Coppola Donato, Lari Martina, Ricci Stefano, Ronchitelli Annamaria, Valentin Frédérique, Thevenet Corinne, Wehrberger Kurt, Grigorescu Dan, Rougier Hélène, Crevecoeur Isabelle, Flas Damien, Semal Patrick, Mannino Marcello A, Cupillard Christophe, Bocherens Hervé, Conard Nicholas J, Harvati Katerina, Moiseyev Vyacheslav, Drucker Dorothée G, Svoboda Jiří, Richards Michael P, Caramelli David, Pinhasi Ron, Kelso Janet, Patterson Nick, Krause Johannes, Pääbo Svante, Reich David: The genetic history of Ice Age Europe. Nature 534(7606): 200-5, 06 2016 Notes: Consortium Paper Contribution: Figure 1.

Mathieson Iain, Lazaridis Iosif, Rohland Nadin, Mallick Swapan, Patterson Nick, Roodenberg Songül Alpaslan, Harney Eadaoin, Stewardson Kristin, Fernandes Daniel, Novak Mario, Sirak Kendra, Gamba Cristina, Jones Eppie R, Llamas Bastien, Dryomov Stanislav, Pickrell Joseph, Arsuaga Juan Luís, de Castro José María Bermúdez, Carbonell Eudald, Gerritsen Fokke, Khokhlov Aleksandr, Kuznetsov Pavel, Lozano Marina, Meller Harald, Mochalov Oleg, Moiseyev Vyacheslav, Guerra Manuel A Rojo, Roodenberg Jacob, Vergès Josep Maria, Krause Johannes, Cooper Alan, Alt Kurt W, Brown Dorcas, Anthony David, Lalueza-Fox Carles, Haak Wolfgang, Pinhasi Ron, Reich David: Genome-wide patterns of selection in 230 ancient Eurasians. Nature 528(7583): 499-503, Dec 2015.

Walter Klaudia, Min Josine L, Huang Jie, Crooks Lucy, Memari Yasin, McCarthy Shane, Perry John R B, Xu ChangJiang, Futema Marta, Lawson Daniel, Iotchkova Valentina, Schiffels Stephan, Hendricks Audrey E, Danecek Petr, Li Rui, Floyd James, Wain Louise V, Barroso Inês, Humphries Steve E, Hurles Matthew E, Zeggini Eleftheria, Barrett Jeffrey C, Plagnol Vincent, Richards J Brent, Greenwood Celia M T, Timpson Nicholas J, Durbin Richard, Soranzo Nicole: The UK10K project identifies rare variants in health and disease. Nature 526(7571): 82-90, Oct 2015 Notes: Consortium Paper Contributiion: Analysis of the age and distribution of rare variants (Extended Data Fig. 9g).

Auton Adam, Brooks Lisa D, Durbin Richard M, Garrison Erik P, Kang Hyun Min, Korbel Jan O, Marchini Jonathan L, McCarthy Shane, McVean Gil A, Abecasis Gonçalo R: A global reference for human genetic variation. Nature 526(7571): 68-74, Oct 2015 Notes: Consortium Paper Contribution: Analysis of the age and distribution of rare variants (Extended Data Fig. 6).

Day Felix R, Hinds David A, Tung Joyce Y, Stolk Lisette, Styrkarsdottir Unnur, Saxena Richa, Bjonnes Andrew, Broer Linda, Dunger David B, Halldorsson Bjarni V, Lawlor Debbie A, Laval Guillaume, Mathieson Iain, McCardle Wendy L, Louwers Yvonne, Meun Cindy, Ring Susan, Scott Robert A, Sulem Patrick, Uitterlinden André G, Wareham Nicholas J, Thorsteinsdottir Unnur, Welt Corrine, Stefansson Kari, Laven Joop S E, Ong Ken K, Perry John R B: Causal mechanisms and balancing selection inferred from genetic associations with polycystic ovary syndrome. Nature communications 6: 8464, Sep 2015 Notes: Consortium Paper Contribution: Scan for selection signals in association results.

Mathieson Iain, McVean Gil: Demography and the age of rare variants. PLoS genetics 10(8): e1004528, Aug 2014.

Rimmer Andy, Phan Hang, Mathieson Iain, Iqbal Zamin, Twigg Stephen R F, Wilkie Andrew O M, McVean Gil, Lunter Gerton: Integrating mapping-, assembly- and haplotype-based approaches for calling variants in clinical sequencing applications. Nature genetics 46(8): 912-8, Aug 2014.

Venn Oliver, Turner Isaac, Mathieson Iain, de Groot Natasja, Bontrop Ronald, McVean Gil: Nonhuman genetics. Strong male bias drives germline mutation in chimpanzees. Science (New York, N.Y.) 344(6189): 1272-5, Jun 2014.

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Last updated: 11/06/2017
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