Sanghee Yun, PhD
Research Assistant Professor of Anesthesiology and Critical Care
Assistant Director, Laboratory of Limbic Circuitry, Mental Function and New Neurons in Postnatal Brains(LMNoP),Children's Hospital of Philadelphia
Department: Anesthesiology and Critical Care
Graduate Group Affiliations
Contact information
Children’s Hospital of Philadelphia
Department of Anesthesiology and Critical Care Medicine
3401 Civic Center Boulevard
Philadelphia, PA 19104
Department of Anesthesiology and Critical Care Medicine
3401 Civic Center Boulevard
Philadelphia, PA 19104
Education:
BA (Biology)
Dong-A University, Busan, South Korea, 2000.
MS (Biological Sciences)
Seoul National University, Seoul, South Korea, 2002.
PhD (Neurobiology and Anatomy)
University of Utah, Salt Lake City, UT, 2009.
Permanent linkBA (Biology)
Dong-A University, Busan, South Korea, 2000.
MS (Biological Sciences)
Seoul National University, Seoul, South Korea, 2002.
PhD (Neurobiology and Anatomy)
University of Utah, Salt Lake City, UT, 2009.
Selected Publications
Yun S, Kiffer FC, Bancroft GL, Guzman CS, Soler I, Haas HA, Shi R, Patel R, Lara-Jiménez J, Kumar PL, Tran FH, Ahn KJ, Rong Y, Luitel K, Shay JW, Eisch AJ: The longitudinal behavioral effects of acute exposure to galactic cosmic radiation in female C57BL/6J mice: implications for deep space missions, female crews, and potential antioxidant countermeasures. Journal of Neurochemistry Aug 2024 Notes: In Press.Siew K, Nestler KA, Nelson C, D’Ambrosio V, Zhong C, Li Z, Grillo A, Wan ER, Patel V, Overbey E, Kim J, Yun S et al: Cosmic kidney disease: an integrated pan-omic, physiological and morphological study into spaceflight-induced renal dysfunction. Nature Communications 11(15(1)): 4923, Jun 2024.
Yun S, Soler I, Tran FH, Haas HA, Shi R, Bancroft GL, Suarez M, de Santis CR, Reynolds RP, Eisch AJ: Behavioral pattern separation and cognitive flexibility are enhanced in a mouse model of increased lateral entorhinal cortex-dentate gyrus circuit activity. Frontiers in Behavioral Neuroscience 17, May 2023.
Guez-Barber D, Colon LM, Raphael D, Wragan MA, Yun S, Eisch AJ: Female and male microglia are not different in the dentate gyrus of postnatal day 10 mice. Neuroscience Letters 803: 137171, April 2023.
Kiffer FC, Luitel K, Tran FH, Patel RA, Guzman CS, Soler I, Xiao R, Shay JW, Yun S, Eisch AJ: Effects of a 33-ion sequential beam galactic cosmic ray analog on male mouse behavior and evaluation of CDDO-EA as a radiation countermeasure. Behavioural brain research 419: 113677, February 2022.
Soler I, Yun S, Reynolds RP, Whoolery CW, Tran FH, Kumar PL, Rong Y, DeSalle MJ, Gibson AD, Stowe AM, Kiffer FC, Eisch AJ+. : Multi-Domain Touchscreen-Based Cognitive Assessment of C57BL/6J Female Mice Shows Whole-Body Exposure to 56Fe Particle Space Radiation in Maturity Improves Discrimination Learning Yet Impairs Stimulus-Response Rule-Based Habit Learning. Frontiers in behavioral neuroscience. 15: 722780, October 2021.
Clark LR, Yun S, Acquah NK, Kumar PL, Metheny HE, Paixao RCC, Cohen AS, Eisch AJ: Mild Traumatic Brain Injury Induces Transient, Sequential Increases in Proliferation, Neuroblasts/Immature Neurons, and Cell Survival: A Time Course Study in the Male Mouse Dentate Gyrus. Frontier in Neuroscience 14: 612749, January 2021.
Tran F, Spears S, Ahn K, Eisch AJ, Yun S : Does chronic systemic injection of the DREADD agonists clozapine-N-oxide or compound 21 change behavior relevant to locomotion, exploration, anxiety, and depression in male non-DREADD-expressing mice? Neuroscience Letter 739: 135432, November 2020.
Bulin SE, Simmons SJ, Richardson DR, Latchney SE, Deutsch HM, Yun S, Eisch AJ: Indices of dentate gyrus neurogenesis are unaffected immediately after or following withdrawal from morphine self-administration compared to saline self-administering control male rats. Behavior Brain Research 381: 112448, March 2020.
Whoolery CW, Yun S, Reynolds RP, Lucero MJ, Soler I, Tran FH, Ito N, Redfield RL, Richardson DR, Shih HY, Rivera PD, Chen BPC, Birnbaum SG, Stowe AM, Eisch AJ: Multi-domain cognitive assessment of male mice shows space radiation is not harmful to high-level cognition and actually improves pattern separation. Scientific Reports 10(1): 2737, February 2020.