Sanghee Yun, PhD
Research Assistant Professor of Anesthesiology and Critical Care
Assistant Director, Laboratory of Limbic Circuitry, Mental Function and New Neurons in Postnatal Brains(LMNoP),Children's Hospital of Philadelphia
Department: Anesthesiology and Critical Care
Contact information
Children’s Hospital of Philadelphia
Department of Anesthesiology and Critical Care Medicine
3401 Civic Center Boulevard
Philadelphia, PA 19104
Department of Anesthesiology and Critical Care Medicine
3401 Civic Center Boulevard
Philadelphia, PA 19104
Education:
BA (Biology)
Dong-A University, Busan, South Korea, 2000.
MS (Biological Sciences)
Seoul National University, Seoul, South Korea, 2002.
PhD (Neurobiology and Anatomy)
University of Utah, Salt Lake City, UT, 2009.
Permanent linkBA (Biology)
Dong-A University, Busan, South Korea, 2000.
MS (Biological Sciences)
Seoul National University, Seoul, South Korea, 2002.
PhD (Neurobiology and Anatomy)
University of Utah, Salt Lake City, UT, 2009.
Selected Publications
Kiffer FC, Luitel K, Tran FH, Patel RA, Guzman CS, Soler I, Xiao R, Shay JW, Yun S, Eisch AJ. : Effects of a 33-ion sequential beam galactic cosmic ray analog on male mouse behavior and evaluation of CDDO-EA as a radiation countermeasure. Behavioural brain research 419: 113677, 2022.Soler I*, Yun S*+, Reynolds RP, Whoolery CW, Tran FH, Kumar PL, Rong Y, DeSalle MJ, Gibson AD, Stowe AM, Kiffer FC, Eisch AJ+. * Co-first authors, +Co-corresponding authors: Multi-Domain Touchscreen-Based Cognitive Assessment of C57BL/6J Female Mice Shows Whole-Body Exposure to 56Fe Particle Space Radiation in Maturity Improves Discrimination Learning Yet Impairs Stimulus-Response Rule-Based Habit Learning. Frontiers in behavioral neuroscience. 231, 2021.
Clark LR, Yun S, Acquah NK, Kumar PL, Metheny HE, Paixao RCC, Cohen AS, Eisch AJ: Mild Traumatic Brain Injury Induces Transient, Sequential Increases in Proliferation, Neuroblasts/Immature Neurons, and Cell Survival: A Time Course Study in the Male Mouse Dentate Gyrus. Frontier in Neuroscience Dec 2020.
Tran FH, Spears SL, Ahn KJ, Eisch AJ, Yun S: Does chronic systemic injection of the DREADD agonists clozapine-N-oxide or Compound 21 change behavior relevant to locomotion, exploration, anxiety, and depression in male non-DREADD-expressing mice? Neuroscience letters. Elsevier, Nov 2020.
Bulin SE, Simmons SJ, Richardson DR, Latchney SE, Deutsch HM, Yun S, Eisch AJ: Indices of dentate gyrus neurogenesis are unaffected immediately after or following withdrawal from morphine self-administration compared to saline self-administering control male rats. Behavior Brain Research 381: 112448, March 2020.
Whoolery CW, Yun S, Reynolds RP, Lucero MJ, Soler I, Tran FH, Ito N, Redfield RL, Richardson DR, Shih HY, Rivera PD, Chen BPC, Birnbaum SG, Stowe AM, Eisch AJ: Multi-domain cognitive assessment of male mice shows space radiation is not harmful to high-level cognition and actually improves pattern separation. Scientific Reports 10(1): 2737, Feb 2020.
Tran F, Spears S, Ahn K, Eisch AJ, Yun S* : Does chronic systemic injection of the DREADD agonists clozapine-N-oxide or compound 21 change behavior relevant to locomotion, exploration, anxiety, and depression in male non-DREADD-expressing mice? Neuroscience Letter 2020 Notes: *Corresponding author.
Zanni G, Deutsch H, Rivera P, Shih HY, LeBlanc J, Amaral W, Lucero M, Redfield R, DeSalle M, Chen BPC, Whoolery C, Reynolds RP, Yun S, Eisch AJ: Whole-Body 12C Irradiation Transiently Decreases Mouse Hippocampal Dentate Gyrus Proliferation and Immature Neuron Number, but Does Not Change New Neuron Survival Rate. International journal of molecular sciences 19(10): 3078, 2018.
Bulin SE, Mendoza ML, Richardson DR, Song KH, Solberg TD, Yun S, Eisch AJ. : Dentate gyrus neurogenesis ablation via cranial irradiation enhances morphine self-administration and locomotor sensitization. Addiction Biology 23(2): 665-675, 2018.
Yun S, Reynolds RP, Petrof I, White A, Rivera PD, Segev A, Gibson AD, Suarez M, DeSalle MJ, Ito N, Mukherjee S, Richardson DR, Kang CE, Ahrens-Nicklas RC, Soler I, Chetkovich DM, Kourrich S, Coulter DA, Eisch AJ: Stimulation of entorhinal cortex-dentate gyrus circuitry is antidepressive. Nature Medicine 24: 658-666, 2018.