Sanghee Yun, PhD

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Research Assistant Professor of Anesthesiology and Critical Care
Department: Anesthesiology and Critical Care

Contact information
The Children’s Hospital of Philadelphia
Department of Anesthesiology and Critical Care Medicine
3401 Civic Center Boulevard
Philadelphia, PA 19104
BA (Biology)
Dong-A University, Busan, South Korea, 2000.
MS (Biological Sciences)
Seoul National University, Seoul, South Korea, 2002.
PhD (Neurobiology and Anatomy)
University of Utah, Salt Lake City, UT, 2009.
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Selected Publications

Zanni G, Deutsch H, Rivera P, Shih HY, LeBlanc J, Amaral W, Lucero M, Redfield R, DeSalle M, Chen BPC, Whoolery C, Reynolds RP, Yun S, Eisch AJ: Whole-Body 12C Irradiation Transiently Decreases Mouse Hippocampal Dentate Gyrus Proliferation and Immature Neuron Number, but Does Not Change New Neuron Survival Rate. International journal of molecular sciences 19(10), 2018.

Bulin SE, Mendoza ML, Richardson DR, Song KH, Solberg TD, Yun S, Eisch AJ. : Dentate gyrus neurogenesis ablation via cranial irradiation enhances morphine self-administration and locomotor sensitization. Addiction Biology 23(2): 665-675, 2018.

Yun S, Reynolds RP, Petrof I, White A, Rivera PD, Segev A, Gibson AD, Suarez M, DeSalle MJ, Ito N, Mukherjee S, Richardson DR, Kang CE, Ahrens-Nicklas RC, Soler I, Chetkovich DM, Kourrich S, Coulter DA, Eisch AJ: Stimulation of entorhinal cortex-dentate gyrus circuitry is antidepressive. Nature Medicine 24: 658-666, 2018.

Whoolery CW, Walker AK, Lucero MJ, Richardson DR, Reynolds RP, Beddow DH, Clark KL, Shih H- Y, LeBlanc JA, Cole MG, Amaral WZ, Mukherjee S, Zhang S, Ahn F, Bulin SE, DeCarolis NA, Rivera PD, Chen BPC, Yun S, Eisch AJ.: Whole Body Exposure to 28Si Radiation Dose-Dependently Disrupts Dentate Gyrus Neurogenesis and Proliferation in the Short-Term and New Neuron Survival and Contextual Fear Conditioning in the Long-Term. Radiation Research 188(5): 532-551, 2017.

Yun S, Donovan MH, Ross MN, Richardson DR, Reister R, Farnbauch LA, Fischer SJ, Riethmacher D, Gershenfeld HK, Lagace DC, Eisch AJ: Stress-induced anxiety- and depressive-like phenotype associated with transient reduction in neurogenesis in adult nestin-CreERT2/diphtheria toxin fragment in transgenic mice. PLoS One 11(1): e0147256, 2016.

Rivera PD, Raghavan RK, Yun S, Latchney SE, McGovern M-K, Birnbaum SG, Eisch AJ: Retrieval of morphine-associated context induces cFos in dentate gyrus neurons. Hippocampus 25(4): 409 - 14, 2015.

Petrik D, Latchney SE, Masiulis I, Yun S, Zhang Z, Wu JI, Eisch AJ: Chromatin remodeling factor Brg1 supports the early maintenance and late responsiveness of nestin-lineage adult neural stem and progenitor cells. Stem Cells 33(12): 3655-3665, 2015.

Sigulinsky CL, German ML, Leung AM, Clark AM, Yun S, Levine EM: Genetic chimeras reveal the autonomy requirements for Vsx2 in embryonic retinal progenitor cells. Neural Development 10(12): doi: 10.1186/s13064-015-0039-5, 2015.

Gordon PJ, Yun S, Clark AM, Monuki ES, Murtaugh LC, Levine EM: Lhx2 balances progenitor maintenance with neurogenic output and promotes competence state progression in the developing retina. The Journal of Neuroscience 33(30): 12197 - 12207, 2013.

Petrik D, Yun S, Latchney SE, Kamrudin S, LeBlanc JA, Bibb JA, Eisch AJ: Early postnatal in vivo gliogenesis from nestin-lineage progenitors requires Cdk5. PLoS One 8(8), e72819 2013 Notes: doi: 10.1371/journal.pone.0072819.

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Last updated: 06/27/2019
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