Alexia Vite, PhD

faculty photo
Research Assistant Professor of Medicine (Cardiovascular Medicine)
Research Associate of Medicine, University of Pennsylvania School of Medicine
Department: Medicine

Contact information
11th Floor Smillow Building
34th Civic Center Blvd.
Philadelphia, PA 19104
Education:
Master (Physiology/Physiopathology)
Pierre et Marie Curie University , 2009.
PhD
Pierre et Marie Curie University , 2013.
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Selected Publications

Vite A, Gandjbakhch E, Hery T, Fressart V, Gary F, Simon F, Varnous S, Hidden Lucet F, Charron P, Villard E: Desmoglein-2 mutations in propeptide cleavage-site causes arrhythmogenic right ventricular cardiomyopathy/dysplasia by impairing extracellular 1-dependent desmosomal interactions upon cellular stress. Europace 22(2): 320-329, Feb 2020

Martí-Pàmies Í, Thoonen R, Seale P, Vite A, Caplan A, Tamez J, Graves L, Han W, Buys ES, Bloch DB, Scherrer-Crosbie M : Deficiency of bone morphogenetic protein-3b induces metabolic syndrome and increases adipogenesis. Am J Physiol Endocrinol Metab 319(2): E363-E375, Aug 2020 Notes: Epub 2020 Jun 30.

Vite A, Matsuura T, Bedi K, Snyder N, Brandimarto J, Ramachandran A, Margulies KB: Effect of Substrate on Adult Human Cardiomyocytes Contractility. Journal of cardiac failure 25(8): S113, August 2019.

Corbin EA*, Vite A*, Peyster EG, Bhoopalam M, Brandimarto J, Wang X, Bennett AI, Clark AT, Cheng X, Turner KT, Musunuru K, Margulies KB: Tunable and Reversible Substrate Stiffness Reveals a Dynamic Mechanosensitivity of Cardiomyocytes. ACS Appl Mater Interfaces 11(23): 20603-20614, Jun 2019 Notes: *Authors contributed equally to this work"

Chen CY, Caporizzo MA, Bedi K, Vite A, Bogush AI, Robison P, Heffler JG, Salomon AK, Kelly NA, Babu A, Morley MP, Margulies KB, Prosser BL : Suppression of detyrosinated microtubules improves cardiomyocyte function in human heart failure. Nat Med 24(8): 1225-1233, Aug 2018 Notes: Epub 2018 Jun 11.

Truitt R, Mu A, Corbin EA, Vite A, Brandimarto J, Ky B, Margulies KB: Increased Afterload Augments Sunitinib-Induced Cardiotoxicity in an Engineered Microtissue Model. JACC Basic Transl Sci 3(2): 265-276, May 2018 Notes: eCollection 2018 Apr.

Vite A, Zhang C, Yi R, Emms S, Radice GL: Alpha-Catenin-Dependent Cytoskeletal Tension Controls Yap Activity in the Heart. Development 145(5), Mar 2018.

Vite A, Li J, Radice LG: New functions for alpha-catenins in health and disease: from cancer to heart regeneration. Cell Tissue Res. (eds.). 360(3): 773-83, Jun 2015.

Li J, Gao E, Vite A, Yi R, Gomez L, Goossens S, van Roy F, and Radice GL: Alpha- catenins control cardiomyocyte proliferation by regulating Yap activity. Circulation Research 116(1): 70-9, Jan 2015.

Vite A, Radice G.L: N-Cadherin/Catenin Complex as a Master Regulator of Intercalated Disc Function. Cell communication and Adhesion 21(3): 169-179, Jun 2014.

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Last updated: 02/18/2021
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