Steven C. Pugliese, MD

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Assistant Professor of Clinical Medicine
Department: Medicine

Contact information
831 Gates building, 3400 Spruce Street
Philadelphia, PA 19104
Office: 215-662-6217
BS (Biology)
Ursinus College, 2003.
MD (Medicine)
Drexel University, 2008.
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Selected Publications

Pugliese Steven C, Kumar Sushil, Janssen William J, Graham Brian B, Frid Maria G, Riddle Suzette R, El Kasmi Karim C, Stenmark Kurt R: A Time- and Compartment-Specific Activation of Lung Macrophages in Hypoxic Pulmonary Hypertension. Journal of immunology (Baltimore, Md. : 1950) 198(12): 4802-4812, Jun 2017.

Mouradian GC, Gaurav R, Pugliese S, El Kasmi K, Hartman B, Hernandez-Lagunas L, Stenmark KR, Bowler RP, Nozik-Grayck E.: Superoxide Dismutase 3 R213G Single-Nucleotide Polymorphism Blocks Murine Bleomycin-Induced Fibrosis and Promotes Resolution of Inflammation. Am J Respir Cell Mol Biol 56(3): 362, March 2017.

Pugliese S, Janssen W, El Kasmi K, Stenmark KR : Transcriptomic Profiling of Lung Macrophage Subsets in Hypoxic Pulmonary Hypertension Reveals a Time and Compartment Specific Activation. ATS Meeting Jun 2016 Notes: Poster presentation.

Robinson Jeffrey C, Pugliese Steven C, Fox Daniel L, Badesch David B: Anticoagulation in Pulmonary Arterial Hypertension. Current hypertension reports 18(6): 47, Jun 2016.

Pugliese Steven C, Bull Todd M: Clinical use of extended-release oral treprostinil in the treatment of pulmonary arterial hypertension. Integrated blood pressure control 9: 1-7, 2016.

Pugliese SC, Poth JM, Janssen WJ, Simonian PL, El Kasmi KC, Stenmark KR. : HIF1 and STAT3 Activated Macrophages Are Spatially and Temporally Regulated In Hypoxic Pulmonary Hypertension ATS A1926, Jun 2015 Notes: Poster presentation.

Pugliese Steven C, Poth Jens M, Fini Mehdi A, Olschewski Andrea, El Kasmi Karim C, Stenmark Kurt R: The role of inflammation in hypoxic pulmonary hypertension: from cellular mechanisms to clinical phenotypes. American journal of physiology. Lung cellular and molecular physiology 308(3): L229-52, Feb 2015.

Stenmark KR, Pugliese S, Poth J, Frid MG, Gerasimovskaya E, Nozik-Grayck E, El Kasmi KC : The effects of hypoxia on inflammation and pulmonary vascular function. Pulmonary Hypertension Basic Science to Clinical Medicine. Maron BA, Zamanian RT Waxman AB. (eds.). Springer, Page: 83-103, 2015.

Robinson JC, Fox DL, Pugliese S, Dempsey JE, Graham BB, Bull T, Badesch D.: Endothelin Receptor Antagonists. Pulmonary Circulation: Diseases and Their Treatment, 4th Ed. Rubin, LJ (eds.). Taylor and Francis Publishers, Page: 337-342, 2015.

El Kasmi Karim C, Pugliese Steven C, Riddle Suzette R, Poth Jens M, Anderson Aimee L, Frid Maria G, Li Min, Pullamsetti Soni S, Savai Rajkumar, Nagel Maria A, Fini Mehdi A, Graham Brian B, Tuder Rubin M, Friedman Jacob E, Eltzschig Holger K, Sokol Ronald J, Stenmark Kurt R: Adventitial fibroblasts induce a distinct proinflammatory/profibrotic macrophage phenotype in pulmonary hypertension. Journal of immunology (Baltimore, Md. : 1950) 193(2): 597-609, Jul 2014.

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Last updated: 11/20/2018
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