Selected Publications

Huijuan Lin, Keren Cheng, Hiroshi Kubota, Yemin Lan, Simone S Riedel, Kazue Kakiuchi, Kotaro Sasaki, Kathrin M Bernt, Marisa S Bartolomei, Mengcheng Luo, P Jeremy Wang: Histone methyltransferase DOT1L is essential for self-renewal of germline stem cells. Genes & Development 1(36): 752-763, Jun 2022.

Simone S Riedel, Congcong Lu, Hongbo M Xie, Kevin Nestler, Marit W Vermunt, Alexandra Lenard, Laura Bennett, Nancy A Speck, Ichiro Hanamura, Julie A Lessard, Gerd A Blobel, Benjamin A Garcia, Kathrin M Bernt: Intrinsically disordered Meningioma-1 stabilizes the BAF complex to cause AML. Molecular cell 81(11): 2332-48, Jun 2021.

Clara Libbrecht, Hongbo M Xie, Molly C Kingsley, Jessica N Haladyna, Simone S Riedel, Fatemeh Alikarami, Alexandra Lenard, Gerard M McGeehan, Patricia Ernst, Kathrin M Bernt: Menin is necessary for long term maintenance of meningioma-1 driven leukemia. Leukemia 35(5): 1405-17, May 2021.

Carina A Bäuerlein, Musga Qureischi, Zeinab Mokhtari, Paula Tabares, Christian Brede, Ana-Laura Jordán Garrote, Simone S Riedel, Martin Chopra, Simone Reu, Anja Mottok, Estibaliz Arellano-Viera, Carolin Graf, Miriam Kurzwart, Katharina Schmiedgen, Hermann Einsele, Matthias Wölfl, Paul-Gerhardt Schlegel, Andreas Beilhack: A T-Cell Surface Marker Panel Predicts Murine Acute Graft-Versus-Host Disease. Frontiers in immunology 11(5): 593321, Jan 2021.

Pamela J. Sung, Simone Sidoli, Simone S. Riedel, Katarzyna Kulej, Hongbo Xie, Bryan Manning, Daniel Tsai, Gerald Wertheim, Benjamin A. Garcia, Sara E. Meyer, Kathrin M. Bernt, Martin P. Carroll: FLT3 Inhibition Downregulates EZH2 in AML and Promotes Myeloid Differentiation. Blood 138(1): 785, 2021.

Molly C Kingsley, Hongbo M Xie, Bo-Rui Chen, Simone S Riedel, Taylor Pastuer, Madelyn K Bollig, Tyler Shank, Clara Libbrecht, Sally P Stabler, Aniruddha J Deshpande, Andrew M Intlekofer, Kathrin M Bernt: Specific patterns of H3K79 methylation influence genetic interaction of oncogenes in AML. Blood advances 4(13): 3109-22, Jul 2020.

Alexandra Lenard, Hongbo Michael Xie, Taylor Pastuer, Tyler Shank, Clara Libbrecht, Molly Kingsley, Simone S Riedel, Zuo-Fei Yuan, Nan Zhu, Tobias Neff, Kathrin M Bernt: Epigenetic regulation of protein translation in KMT2A-rearranged AML. Experimental hematology 85(1): 57-69, May 2020.

SS Riedel, A Lenard, K Nestler, C Lu, HM Xie, B Garcia, KM Bernt: SWI/SNF Dysregulation through a Prion-like Domain Causes AML. 61st ASH Annual Meeting and Exposition, Orlando, FL, USA Dec 2019.

SS Riedel, A Lenard, K Nestler, C Lu, B Garcia, KM Bernt: The prion-like domain of MN1 drives a poor prognostic AML subgroup through mSWI/SNF dysregulation. FASEB SRC “The Hematologic Malignancies Conference”, Snowmass, CO, USA Jul 2019.

MC Kingsley, SS Riedel, HM Xie, SP Stabler, T Pastuer, KM Bernt: Tight Regulation of H3K79 Methylation Levels in KMT2A-Rearranged AML. 60th ASH Annual Meeting and Exposition, San Diego, CA, USA Dec 2018.