Daniel P Kelly, MD

faculty photo
Willard and Rhoda Ware Professor of Diabetes and Metabolic Diseases
Department: Medicine
Graduate Group Affiliations

Contact information
3400 Civic Center Blvd.
Smilow Center for Translational Research
11-122
Philadelphia, PA 19104
Office: 215-898-0768
Lab: 215-898-2374
Education:
B.S. (Biology)
University of Illinois, 1978.
M.D. (Medicine )
University of Illinois College of Medicine, Chicago, Illinois, 1982.
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Selected Publications

Tomoya Sakamoto, Daniel Kelly: A Case for Adaptive Cardiac Hypertrophic Remodeling is CITED. Circulation Research August 2020.

Davidson MT, Grimsrud PA, Lai L, Draper JA, Fisher-Wellman KH, Narowski TM, Koves TR, Kelly DP, Muoio DM: Extreme Acetylation of the Cardiac Mitochondrial Proteome Does Not Promote Heart Failure. Circulation Research Jul 2020.

Tomoya Sakamoto , Timothy R Matsuura , Shibiao Wan , David M Ryba , Junil Kim , Kyoung-Jae Won , Ling Lai , Christopher Petucci , Nataliya Petrenko , Kiran Musunuru , Rick B Vega , and Daniel P Kelly: A Critical Role for Estrogen-related Receptor Signaling in Cardiac Maturation. Circulation Research Jun 2020.

Selvaraj S, Kelly DP, Margulies KB: Implications of Altered Ketone Metabolism and Therapeutic Ketosis in Heart Failure. Circulation Jun 2020.

Zamani P, Proto EA, Mazurek J, Prenner S, Margulies KB, Townsend RR, Kelly DP, Arany ZP, Poole DC, Wagner PD, Chirinos JA: Peripheral Determinants of Oxygen Utilization in Heart Failure with Preserved Ejection Fraction: Central Role of Adiposity. JACC: Basic to Transnational Science March 2020.

Timothy R. Matsuura, Teresa C. Leone, Daniel P. Kelly: Fueling Cardiac Hypertrophy. Circulation Research 126(2): 197 - 199, Jan 2020.

Yurista SR, Matsuura TR, Silljé HHW, Nijholt KT, McDaid KS, Shewale SV, Leone TC, Newman JC, Verdin E, Oberdorf-Maass SU, van Veldhuisen DJ, de Boer RA, Kelly DP, Westenbrink BD: Ketone ester treatment improves cardiac function and reduces pathologic remodeling in pre-clinical models of heart failure. Circ Heart Failure In press 2020.

Lombardi A, Gibb A, Arif E, Kolmetzky D, Tomar D, Luongo T, Jadiya P, Murray E, Lorkiewicz P, Hajnoczky G, Murphy E, Arany Z, Kelly DP, Margulies K, Hill B, Elrod J: Mitochondrial calcium exchange links metabolism with the epigenome to control cellular differentiation. Nature Communications 10(1): 4509, Oct 2019.

Trevino MB, Zhang X, Standley RA, Wang M, Han X, Reis FCG, Periasamy M, Yu G, Kelly DP, Goodpaster BH, Vega RB, Coen PM: Loss of mitochondrial energetics is associated with poor recovery of muscle function but not mass following disuse atrophy. Am J Physiol Endocrinol Meta 317(5): E899-E910, Sept 2019.

Ho KL, Zhang L, Wagg C, Al Batran R, Gopal K, Levasseur J, Leone T, Dyck JRB, Ussher JR, Muoio DM, Kelly DP, Lopaschuk GD: Increased ketone body oxidation provides additional energy for the failing heart without improving cardiac efficiency. Cardiovasc Res 115(11): 1606-1616, Sep 2019.

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Last updated: 11/03/2020
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