Ran Barzilay, MD, PhD
Assistant Professor of Psychiatry
Child & Adolescent Psychiatrist Research Scientist, Lifespan Brain Institute, Department of Child and Adolescent Psychiatry and Behavioral Sciences, Children's Hospital of Philadelphia
Department: Psychiatry
Graduate Group Affiliations
Contact information
10th Floor, Gates Building
Hospital of the University of Pennsylvania
3400 Spruce St.
Philadelphia, PA 19104
Hospital of the University of Pennsylvania
3400 Spruce St.
Philadelphia, PA 19104
Office: 215-662-7559
Fax: 215-662-7903
Fax: 215-662-7903
Publications
Education:
BSc (Preclinical M.D. Studies)
Tel Aviv University, 2004.
PhD (Neuroscience)
Tel Aviv University, 2008.
MD
Tel Aviv University, 2011.
Permanent linkBSc (Preclinical M.D. Studies)
Tel Aviv University, 2004.
PhD (Neuroscience)
Tel Aviv University, 2008.
MD
Tel Aviv University, 2011.
Description of Clinical Expertise
Child and Adolescent PsychiatryDescription of Research Expertise
In BarziLab, we are interested in what drives variability in the development of brain and behavior in children and adolescents who develop under stress. We are especially interested in understanding mechanisms of risk and resilience leading to youth suicidal behavior. Using large datasets of youth who have been genotyped and deeply phenotyped, we study how a myriad of environmental exposures (such as trauma and poverty) dynamically interact amongst themselves (i.e., within the exposome), as well as with biological factors (genetic, epigenetic, immune) to drive suicidal behavior. We are committed to conduct impactful translational science that will help reduce teen suicide.Selected Publications
Robinson H, Dave N, Barzilay R, Wagner A, Kells N, Keller AS: The effect of the "exposome" on developmental brain health and cognitive outcomes. Neuropsychopharmacology 51(1): 169-184, January 2026 Notes: doi: 10.1038/s41386-025-02180-6. Epub 2025 Aug 5.Jones JD, Penney C, Davis M, Barzilay R, Tweedy E, Tsui F, Young JF: Trends in Adolescent Depression and Suicide Risk Screening and Symptom Monitoring in a Large Primary Care Network. Acad Pediatr 26(3): 103211, December 2025 Notes: doi: 10.1016/j.acap.2025.103211. Epub ahead of print.
Gatavins MM, Tran KT, Visoki E, Moore TM, Hoffman KW, Shilton T, Schultz LM, Almasy L, Mancini AD, Barzilay R.: Adolescent Depressive Symptom Trajectories From Before to After the COVID-19 Pandemic. JAMA Netw Open 8(12): e2545987, December 2025 Notes: doi: 10.1001/jamanetworkopen.2025.45987.
Keller AS, Shetty A, Barzilay R, Calkins ME, Chong YS, Dave N, Fair DA, Gluckman PD, Gur RE, Gur RC, Mackey AP, Meaney MJ, Moore LA, Moore TM, Satterthwaite TD, Tan AP, Tervo-Clemmens B, Larsen BS: Cognition varies across the calendar year in multiple large-scale datasets. Proc Natl Acad Sci U S A 122(51): e2506054122. December 2025 Notes: doi: 10.1073/pnas.2506054122. Epub 2025 Dec 16.
Barzilay R.: Postnatal vs Prenatal Maternal Stress and Offspring Neurodevelopment. JAMA Netw Open 8(10): e2540917, October 2025 Notes: doi: 10.1001/jamanetworkopen.2025.40917.
Sha Z, Sun KY, Jung B, Barzilay R, Moore TM, Almasy L, Forsyth JK, Prem S, Gandal MJ, Seidlitz J, Glessner JT, Alexander-Bloch AF.: Copy Number Variant Architecture of Child Psychopathology and Cognitive Development in the ABCD Study. Am J Psychiatry 182: 763-778, Aug 2025.
White, L.K., Himes, M.M., Waller, R., Njoroge, W.F.M., Chaiyachati, B.H., Barzilay, R., Kornfield, S.L., Burris, H.H., Seidlitz, J., Parish-Morris, J., Brady, R.G., Gerstein, E.D., Laney, N., Gur, R.E., Duncan, A.: The Influence of Pandemic-Related Worries During Pregnancy on Child Development at 12 Months. Child Psychiatry Hum Dev 56(4), August 2025 Notes: doi: 10.1007/s10578-023-01605-x. Epub 2023 Oct 8.
Ered A, Dietterich TE, Shahriar SS, Wong TY, Moore TM, Ruparel K, Barzilay R, Taylor JH, Calkins ME, Gur RC, Gur RE.: Environmental Adversity Is Associated With Attenuated Positive Symptoms and Complex Cognition in a Long-term Follow-up of the Philadelphia Neurodevelopmental Cohort. Schizophr Bull 51: 871-882, Jul 2025.
Visoki E, Moore TM, Ruiz VM, Fein JA, Calkins ME, Gur RC, Benton TD, Gur RE, Tsui FR, Barzilay R.: Prediction of Adolescent Suicide Attempt by Integrating Clinical, Neurocognitive and Geocoded Neighborhood Environment Data. Schizophr Bull 51: 895-905, Jul 2025.
Calkins ME, Butler ER, Moore TM, Ered A, Taylor JH, White LK, Barzilay R, Ruparel K, Larsen B, Shahriar SS, Dietterich TE, Roalf DR, Wolf DH, Satterthwaite TD, Gur RC, Gur RE.: Longitudinal Trajectories of Clinical Features in Community Youth With Recurrent Psychosis Spectrum Symptoms: Findings From the Philadelphia Neurodevelopmental Cohort. Schizophr Bull 51: 858-870, Jul 2025.