Benedicte Lefebvre, MD
Assistant Professor of Clinical Medicine (Cardiovascular Medicine)
Adult Scientific Assistant Director, Cardiovascular Phenotyping Unit, Center for Human Phenomic Science, University of Pennsylvania, Perelman School of Medicine
Fellowship Director, Thalheimer Center of Cardio-Oncology, University of Pennsylvania, Perelman School of Medicine
Department: Medicine
Contact information
11-134 South Pavilion
Perelman Center for Advanced Medicine
3400 Civic Center Blvd
Philadelphia, PA 19104
Perelman Center for Advanced Medicine
3400 Civic Center Blvd
Philadelphia, PA 19104
Education:
Pre-Univ (Health Sciences)
Collège Laflèche, Canada, 2007.
Pre-Med (Preparatory Medicine)
McGill University, Canada, 2008.
MD (Doctor of Medicine)
McGill University, Canada, 2012.
Permanent linkPre-Univ (Health Sciences)
Collège Laflèche, Canada, 2007.
Pre-Med (Preparatory Medicine)
McGill University, Canada, 2008.
MD (Doctor of Medicine)
McGill University, Canada, 2012.
Selected Publications
Takeshi Onoue, Yu Kang, Bénédicte Lefebvre, Amanda M Smith, Srinivas Denduluri, Michael G Fradley, Jesse Chittams, Joseph R Carver, Marielle Scherrer-Crosbie: Impact of atrial fibrillation on heart failure in patients treated with anthracycline chemotherapy. American Journal of Cardiology November 2023.James W. Schurr, Ian Sigal, Asad Usman, Prakash Patel, Benedicte Lefebvre, Kristy Kurcik, Pavan Atluri, Michael Acker, Christian Bermudez, J. Eduardo Rame, Thomas Hanff, Marisa Cevasco, Joyce Wald: Effect of Anesthesia on Cardiac Hemodynamics in Patients Undergoing Durable LVAD Implantation: The EACH LVAD Study. ASAIO J 69(10): 907-914, Oct 2023.
Bénédicte Lefebvre, Yu Kang, Azin Vakilpour, Takeshi Onoue, Noelle V. Frey, Priya Brahmbhatt, Brian Huang, Kemi Oladuja, Daniel Koropeckyj-Cox, Courteney Wiredu, Amanda M. Smith MA, Jesse Chittams, Joseph Carver, Marielle Scherrer-Crosbie: Incidence of MACE in Patients Treated with CAR-T Cell Therapy: A Prospective Study. J Am Coll Cardiol CardioOnc Oct 2023.
Takeshi Onoue, Yu Kang, Bénédicte Lefebvre, Amanda M. Smith, Srinivas Denduluri, Joseph Carver, Michael G. Fradley, Jesse Chittams, and Marielle Scherrer-Crosbie: The Association of Metformin With Heart Failure in Patients With Diabetes Mellitus Receiving Anthracycline Chemotherapy. J Am Coll Cardiol CardioOnc Aug 2023.
Michael G Fradley, Nam H K Nguyen, David Madnick, Yiqing Chen, Angela DeMichele, Igor Makhlin, Susan Dent, Benedicte Lefebvre, Joseph Carver, Jenica N Upshaw, David DeRemer, Bonnie Ky, Avirup Guha, Yan Gong: Adverse Cardiovascular Events Associated With Cyclin-Dependent Kinase 4/6 Inhibitors in Patients With Metastatic Breast Cancer. J Am Heart Assoc 12(12): e029361, Jun 2023.
Kent DM, Saver JL, Kasner SE, Nelson J, Wang AY, Bannuru RR, Carroll JD, Chatellier G, Derumeaux G, Furlan AJ, Herrmann HC, Jüni P, Kim JS, Koethe B, Lee PH, Lefebvre B, Mattle HP, Meier B, Reisman M, Smalling RW, Soendergaard L, Song JK, Mas JL, Thaler DE.: Evaluating Therapies to Prevent Future Stroke in Patients with Patent Foramen Ovale-Related Strokes — The SCOPE Study . Washington (DC): Patient-Centered Outcomes Research Institute (PCORI) Apr 2023.
Biniyam G Demissei, Natasha A Vedage, Rebecca A Hubbard, Amanda M Smith, Jade Chung, Bénédicte Lefebvre, Kelly D Getz, Paaladinesh Thavendiranathan, Hari K Narayan, Bonnie Ky: Longitudinal Right Ventricular Systolic Function Changes in Breast Cancer Patients Treated With Cardiotoxic Cancer Therapy. JACC CardioOncology 4(4): 552-554, Nov 2022.
Jean-Louis Mas, Jeffrey L Saver, Scott E Kasner, Jason Nelson, John D Carroll, Gilles Chatellier, Geneviève Derumeaux, Anthony J Furlan, Howard C Herrmann, Peter Jüni, Jong S Kim, Benjamin Koethe, Pil Hyung Lee, Benedicte Lefebvre, Heinrich P Mattle, Bernhard Meier, Mark Reisman, Richard W Smalling, Lars Sondergaard, Jae-Kwan Song, David E Thaler, David M Kent: Association of Atrial Septal Aneurysm and Shunt Size With Stroke Recurrence and Benefit From Patent Foramen Ovale Closure. JAMA Neurol 79(11): 1175-1179, Nov 2022.
Laura B. Vater, Benedicte Lefebvre, Anita Turk, Suparna C. Clasen: Fluoropyrimidine Cardiotoxicity: Incidence, Outcomes, and Safety of Rechallenge. Curr Oncol Rep 24(7): 943-950, Mar 2022.
David Madnick, Maani Kamal, Tarek Zghaib, Chris Domenico, Joseph Carver, Benedicte Lefebvre, Joyce Wald, Nosheen Reza: FAILURE OR FLARE? CARDIOGENIC SHOCK IN A PATIENT WITH IMMUNE CHECKPOINT INHIBITOR-ASSOCIATED MYOCARDITIS AND CHRONIC HEART FAILURE (HF). J Am Coll Cardiol 79(9): 2672, Mar 2022.