Benedicte Lefebvre, MD
Assistant Professor of Clinical Medicine (Cardiovascular Medicine)
Adult Scientific Assistant Director, Cardiovascular Phenotyping Unit, Center for Human Phenomic Science, University of Pennsylvania, Perelman School of Medicine
Fellowship Director, Thalheimer Center for Cardio-Oncology, University of Pennsylvania, Perelman School of Medicine
Department: Medicine
Contact information
11-134 South Pavilion
Perelman Center for Advanced Medicine
3400 Civic Center Blvd
Philadelphia, PA 19104
Perelman Center for Advanced Medicine
3400 Civic Center Blvd
Philadelphia, PA 19104
Education:
Pre-Univ (Health Sciences)
Collège Laflèche, Canada, 2007.
Pre-Med (Preparatory Medicine)
McGill University, Canada, 2008.
MD (Doctor of Medicine)
McGill University, Canada, 2012.
Permanent linkPre-Univ (Health Sciences)
Collège Laflèche, Canada, 2007.
Pre-Med (Preparatory Medicine)
McGill University, Canada, 2008.
MD (Doctor of Medicine)
McGill University, Canada, 2012.
Selected Publications
Lefebvre, Scherrer-Crosbie: Hematology: Basic Principles and Practice Chapter: Onco-cardiology: Focus on Cardiac Complications of Hematologic Treatments. Textbook 2026.Lefebvre, Carver: ESC Textbook of Cardiovascular Medicine, 4th Edition. Textbook. Oxford University Press, 2026 Notes: Chapter underway.
Azin Vakilpour, Yulei Cao, Benedicte Lefebvre, Srinivas Denduluri, Amanda M Smith, Marielle Scherrer-Crosbie: CARDIOVASCULAR ADVERSE EVENTS AFTER BORTEZOMIB THERAPY IN PATIENTS WITH MULTIPLE MYELOMA: A LARGE REAL-WORLD DATA ANALYSIS. Journal of the American College of Cardiology April 2025.
Eva Berlin, Kyunga Ko, Lin Ma, Ian Messing, Casey Hollawell, Amanda M Smith, Neil K Taunk, Vivek Narayan, Jenica N Upshaw, Amy S Clark, Payal D Shah, Hayley Knollman, Saveri Bhattacharya, Daniel Koropeckyj-Cox, Jessica Wang, Nikhil Yegya-Raman, Ivy S Han, Benedicte Lefebvre, Tang Li, Nicholas S Wilcox, Wonyoung Jung, Jinbo Chen, Gary M Freedman, Bonnie Ky : Cardiac Effects of Modern Breast Radiation Therapy in Patients Receiving Systemic Cancer Therapy. JACC CardioOncology February 2025.
Takeshi Onoue, Andrew H Matthews, Azin Vakilpour, Yu Kang, Bénédicte Lefebvre, Amanda M Smith, Shannon R McCurdy, Michael G Fradley, Joseph Carver, Jesse Chittams, Marielle Scherrer-Crosbie: Cardiotoxicity of venetoclax in patients with acute myeloid leukemia: comparison with anthracyclines. Cardio-Oncology November 2024.
Yu Kang, Benedicte Lefebvre, Ingrid Marti Pamies, Saar I Gill, Abigail G Doucette, Srinivas Denduluri, Amanda M Smith, Shannon McCurdy, Selina Luger, Joseph Carver, Marielle Scherrer-Crosbie: Symptomatic Heart Failure and Clonal Hematopoiesis-Related Mutations in Patients With Acute Myeloid Leukemia. The American Journal of Cardiology September 2024.
Andy Y Wang, Peter M Rothwell, Jason Nelson, Jeffrey L Saver, Scott E Kasner, John Carroll, Jean-Louis Mas, Geneviève Derumeaux, Gilles Chatellier, Anthony J Furlan, Howard C Herrmann, Peter Jüni, Jong S Kim, Benjamin Koethe, Pil H Lee, Benedicte Lefebvre, Heinrich P Mattle, Bernhard Meier, Mark Reisman, Richard W Smalling, Lars Sondergaard, Jae-Kwan Song, Emanuele Di Angelantonio, Marco DiTullio, Mitchell S V Elkind, Shunichi Homma, Cheryl Jaigobin, Patrik Michel, Marie-Luise Mono, Krassen Nedeltchev, Federica Papetti, Joaquin Serena, Christian Weimar, Linxin Li, Sara Mazzucco, Louise E Silver, David van Klaveren, David E Thaler, David M Kent: Patent Foramen Ovale Closure in Older Patients With Stroke: Patient Selection for Trial Feasibility. Neurology May 2024.
Janane Maheswaran, Moezedin Javad Rafiee, Sydney Cordes, Benedicte Lefebvre, Michael Chetrit: Multimodality Imaging of Acute Myocarditis in Cytokine Release Syndrome (CRS) following CAR-T therapy. Canadian Journal of Cardiology April 2024.
Azin Vakilpour, Bénédicte Lefebvre, Catherine Lai, Marielle Scherrer-Crosbie : Heartbreaker: Detection and prevention of cardiotoxicity in hematological malignancies. Blood Reviews March 2024.
Kasey J Leger, Nora Robison, Hari K Narayan, Amanda M Smith, Tenaadam Tsega, Jade Chung, Amber Daniels, Zhen Chen, Virginia Englefield, Biniyam G Demissei, Benedicte Lefebvre, Gemma Morrow, Ilona Dizon, Robert B Gerbing, Reena Pabari, Kelly D Getz, Richard Aplenc, Jessica A Pollard, Eric J Chow, W H Wilson Tang, William L Border, Ritu Sachdeva, Todd A Alonzo, E Anders Kolb, Todd M Cooper, Bonnie Ky : Rationale and design of the Children's Oncology Group study AAML1831 integrated cardiac substudies in pediatric acute myeloid leukemia therapy. Frontiers in Cardiovascular Medicine December 2023.