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Susan Sotardi, MD, MS

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Assistant Professor of Radiology at the Children's Hospital of Philadelphia
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Active Medical Staff, Hospital of the University of Pennsylvania
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Active Medical Staff, Chester County Hospital
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Active Medical Staff, Pennsylvania Hospital
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Attending Pediatric Neuroradiologist, Children's Hospital of Philadelphia, Division of Neuroradiology, Department of Radiology, Philadelphia, PA
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Faculty, Department of Biomedical and Health Informatics (DBHi), Children's Hospital Research Institute, Children's Hospital of Philadelphia, Philadelphia, PA
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Faculty, D3b Center for Data-Driven Discovery in Medicine, Children's Hospital of Philadelphia Research Institute, Philadelphia, PA
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Director, Informatics and Artificial Intelligence (AI), Children's Hospital of Philadelphia, Department of Radiology, Philadelphia, PA
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Richard Markowitz Endowed Chair of Artificial Intelligence in Pediatric Radiology, Children's Hospital of Philadelphia, Department of Radiology, Philadelphia, PA
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Medical Director of Enterprise Imaging, Children's Hospital of Philadelphia, Department of Radiology, Philadelphia, PA
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Department: Radiology
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Children's Hospital of Philadelphia
1f Department of Radiology
39 3401 Civic Center Blvd
Philadelphia, PA 19104
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2e Office: 215-590-7000
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Email: sotardis@chop.edu
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13 Education:
21 7 BS 3c (Molecular and Cellular Biology, Summa Cum Laude) c
3a University of Arizona, Tucson, AZ, 2002.
 21 b MD, MS 56 (Combined Degree Program: Medical Doctorate & MS Clinical Research Methods) c
5b Albert Einstein College of Medicine, Yeshiva University, Bronx, NY, 2011.
 21 a MSEng 41 (Data Science, with concentration in Machine Learning) c
4e Department of Engineering, University of Pennsylvania, 2022.
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Selected Publications

1eb Mandal, A. S., Dorfschmidt, L., Schabdach, J. M., Gardner, M., Yerys, B. E., Bethlehem, R. A. I., Sotardi, S., Henry, M. K., Wood, J. N., Chaiyachati, B. H., Alexander-Bloch, A., & Seidlitz, J.: Reference Trajectories of Extra-Axial Cerebrospinal Fluid during Childhood and Adolescence Defined in a Clinically Acquired MRI Dataset. Radiology. Artificial intelligence 8(1), January 2026 Notes: DOI: 10.1148/ryai.250123.

 28a Rauland, A., Meisler, S. L., Alexander-Bloch, A. F., Bagautdinova, J., Baller, E. B., Gur, R. E., Gur, R. C., Luo, A. C., Moore, T. M., Popovych, O. V., Reetz, K., Roalf, D. R., Shinohara, R. T., Sotardi, S., Sydnor, V. J., Vossough, A., Eickhoff, S. B., Cieslak, M., & Satterthwaite, T. D: White Matter Bundle Reconstruction From Single-Shell Diffusion Magnetic Resonance Imaging: Test-Retest Reliability and Predictive Capability Across Orientation Distribution Function Reconstruction Methods. Human brain mapping 46(17): e70429, December 2025 Notes: DOI: 10.1002/hbm.70429.

 19d Sotardi, S., Flowers, C., Larsen, E., Sinti-Ycochea, M., Johnson, A. M., & Anupindi, S.: Creating a Cyberattack Plan for Radiology Operations: A Practical Pediatric Perspective. Journal of the American College of Radiology. Journal of the American College of Radiology 22(10): 1148-1156, October 2025 Notes: DOI:10.1016/j.jacr.2025.07.017.

 262 Mercedes, L., Buczek, M. J., Kafadar, E., DiDomenico, G., Jung, B., Zimmerman, D., Schabdach, J. M., Himes, M. M., Sotardi, S., Vossough, A., Driesbaugh, K. H., Moore, T., Barzilay, R., Calkins, M. E., Gur, R. E., Roalf, D. R., Satterthwaite, T. D., White, L. K., & Alexander-Bloch, A.: A prospective protocol for remotely investigating brain-behaviour-genetics associations in adolescent patients in a paediatric health system with pre-existing clinical brain MRIs. BMJ open 15(10), October 2025 Notes: DOI: 10.1136/bmjopen-2025-106431.

 24a Zimmerman, D., Mandal, A. S., Jung, B., Buczek, M. J., Schabdach, J. M., Karandikar, S., Kafadar, E., Gardner, M., Daniali, M., Mercedes, L., Kohler, S., Abdel-Qader, L., Gur, R. E., Roalf, D. R., Satterthwaite, T. D., Williams, R., Padmanabhan, V., Seidlitz, J., White, L. K., Sotardi, S., … Alexander-Bloch, A.: Systematic protocol to identify 'clinical controls' for paediatric neuroimaging research from clinically acquired brain MRIs. BMJ open 15(10), October 2025 Notes: DOI: 10.1136/bmjopen-2025-106428.

 23c Zimmerman, D., Mandal, A. S., Jung, B., Buczek, M. J., Schabdach, J. M., Karandikar, S., Kafadar, E., Gardner, M., Daniali, M., Mercedes, L., Kohler, S., Abdel-Qader, L., Gur, R. E., Roalf, D., Satterthwaite, T. D., Williams, R., Padmanabhan, V., Seidlitz, J., White, L. K., Sotardi, S., … Alexander-Bloch, A. : A systematic protocol to identify "clinical controls" for pediatric neuroimaging research from clinically acquired brain MRIs. bioRxiv August 2025 Notes: DOI: 10.1101/2025.06.25.661530.

 1d0 Schabdach, J. M., Williams, R. M. S., Logan, J., Padmanabhan, V., D'Aiello Iii, R., Mclaughlin, J., Gonzalez, A., Krause, E. M., Tasian, G. E., Sotardi, S., & Alexander-Bloch, A. F.: From Scanner to Science: Reusing Clinically Acquired Medical Images for Research. AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science Page: 471-480, June 2025.

 180 Schabdach JM, Williams RMS, Logan J, Padmanabhan V, D'Aiello Iii R, Mclaughlin J, Gonzalez A, Krause EM, Tasian GE, Sotardi S, Alexander-Bloch AF.: From Scanner to Science: Reusing Clinically Acquired Medical Images for Research. AMIA Joint Summits on Translational Science proceedings Page: 471-480, June 2025.

 121 Alkhulaifat D, Vidal L, Larsen E, Serai SD, Sinti-Ycochea M, Mecca P, Orfe L, Sotardi S.: MRI safety-developing the right culture. Pediatric radiology 55(5): 895-901, May 2025 Notes: DOI: 10.1007/s00247-025-06179-5.

 1d3 Clatot J, Thompson CH, Sotardi S, Jiang J, Trivisano M, Balestrini S, Ward DI, Ginn N, Guaragni B, Malerba L, Vakrinou A, Sherer M, Helbig I, Somarowthu A, Sisodiya SM, Ben-Shalom R, Guerrini R, Specchio N, George AL Jr, Goldberg EM.: Rare dysfunctional SCN2A variants are associated with malformation of cortical development. Epilepsia 66(3): 914-928, March 2025 Notes: DOI: 10.1111/epi.18234.

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