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Peter B. Noël, M.S., Ph.D.
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Associate Professor of Radiology
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Director of CT Research, Department of Radiology
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Co-Director, Center for Imaging Research with Radiation in Radiology (CIR³)
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Director, Computed Tomography Center (CTC)
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Department: Radiology
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Contact information
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Hospital of the University of Pennsylvania
1f Department of Radiology
46 3400 Spruce Street, One Silverstein
Philadelphia, PA 19104
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1f Department of Radiology
46 3400 Spruce Street, One Silverstein
Philadelphia, PA 19104
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Office: +1 (215) 898-8212
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Publications
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Links
e1 Search PubMed for articles
92 PixelPrint - lifelike computed tomography (CT) phantoms
79 Google Scholar
83 Laboratory for Advanced Computed Tomography Imaging
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e1 Search PubMed for articles
92 PixelPrint - lifelike computed tomography (CT) phantoms
79 Google Scholar
83 Laboratory for Advanced Computed Tomography Imaging
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Education:
21 c B. Eng. 23 (Biomedical Engineering) c
4d Technische Hochschule Mittelhessen, Gießen, Germany, 2003.
21 c M. Eng. 23 (Biomedical Engineering) c
4d Technische Hochschule Mittelhessen, Gießen, Germany, 2004.
21 9 M.S. 2d (Computer Science and Engineering) c
6c University at Buffalo, The State University of New York, Buffalo, NY, United States, 2007.
21 a Ph.D. 2d (Computer Science and Engineering) c
6c University at Buffalo, The State University of New York, Buffalo, NY, United States, 2009.
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Permanent link21 c B. Eng. 23 (Biomedical Engineering) c
4d Technische Hochschule Mittelhessen, Gießen, Germany, 2003.
21 c M. Eng. 23 (Biomedical Engineering) c
4d Technische Hochschule Mittelhessen, Gießen, Germany, 2004.
21 9 M.S. 2d (Computer Science and Engineering) c
6c University at Buffalo, The State University of New York, Buffalo, NY, United States, 2007.
21 a Ph.D. 2d (Computer Science and Engineering) c
6c University at Buffalo, The State University of New York, Buffalo, NY, United States, 2009.
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Description of Research Expertise
45b For over a decade Dr. Noël directs a research program with a broad focus on developing x-ray and Computed Tomography (CT) technology. A central component of his research is the harmonization between hardware and software, reconstruction, and post-processing to achieve integrated clinical solutions. He has built an extensive foundation for facilitating the clinical translation of novel diagnostic imaging technology; one example is the introduction of photon-counting CT. A parallel effort is the development of novel 3D printed CT phantoms, which serve as a central ingredient for clinical and research tasks around evaluation and standardization. Recently he and his team introduced patient-specific lung phantoms, which are available to the larger research community. On the other end of the spectrum, his research program contributes to basic x-ray physics questions focusing on phase-contrast and dark-field imaging. His publication record not only includes more than 190 peer-reviewed publications in international journals, but also a patent portfolio in the areas of x-ray and CT imaging.e 29
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17e Im, J. Y., Micah, N., Perkins, A. E., Mei, K., Geagan, M., & Noël, P. B. : PixelPrint4D: A 3D printing method of fabricating patient-specific deformable CT phantoms for respiratory motion applications. Investigative Radiology Apr 2025 Notes: https://doi.org/10.1097/RLI.0000000000001182; Epub ahead of print.
1d4 Rosario-Berríos, D. N., Pang, A., Mossburg, K., Kim, J., Marrero, V. V., Yoon, S., Gupta, M., Lenz, O. C., Liu, L. P., Kian, A. C., Rivera, K. L., Shin, S., Noël, P. B., Lennon, E. M., & Cormode, D. P. : CT imaging of and therapy for inflammatory bowel disease via low molecular weight dextran coated ceria nanoparticles. Nanoscale 17(16): 10356-10370, Apr 2025 Notes: doi: 10.1039/d4nr04994b.
1bb Rosario-Berríos DN, Pang A, Liu LP, Maidment PSN, Kim J, Yoon S, Nieves LM, Mossburg KJ, Adezio A, Noël PB, Lennon EM, Cormode DP: The Effect of the Size of Gold Nanoparticle Contrast Agents on CT Imaging of the Gastrointestinal Tract and Inflammatory Bowel Disease. Bioconjug Chem 36(2): 233-244, Feb 2025 Notes: doi: 10.1021/acs.bioconjchem.4c00507. Epub 2025 Jan 9.
1c5 Rosario-Berrios, D. N., Pang, A., Liu, L., Maidment, P. S., Kim, J., Yoon, S., Nieves, L. M., Mossburg, K., Adezio, A., Noël, P. B., Lennon, E. M., & Cormode, D. P. : The effect of the size of gold nanoparticle contrast agents on CT imaging of the gastrointestinal tract and inflammatory bowel disease. Bioconjugate Chemistry Feb 2025 Notes: doi: 10.1021/acs.bioconjchem.4c00507.
16d Rybertt, M. V., Liu, L. P., Mathew, M., Sahbaee, P., Litt, H. I., & Noël, P. B.: Impact of Vessel Size, Dose Levels, and Body Habitus on Iodine Quantification in Cardiovascular Photon-Counting Computed Tomography. British Journal of Radiology 2025 Notes: https://doi.org/10.1093/bjr/tqaf181.
166 Sandvold, O. F., Proksa, R., Daerr, H., Perkins, A. E., Brown, K. M., Koehler, T., Manjeshwar, R.M. & Noël, P. B. : Efficient spectral data reduction for accurate iodine quantification in multi-energy CT. Scientific Reports 15, 2025 Notes: https://doi.org/10.1038/s41598-025-11270-w.
172 Liu, L. P., Pasyar, P., Liu, F., Cao, Q., Sandvold, O. F., Sahbaee, Shinohara, T., P., Litt, H. I., & Noël, P. B. : Assessing the Stability of Photon-Counting CT: Insights from a Two-Year Longitudinal Study. European Radiology Dec 2024 Notes: doi: 10.1007/s00330-024-11244-y. Epub ahead of print.
19d Liu, L. P., Pua, R., Dieckmeyer, M., Shapira, N., Sahbaee, P., Gang, G. J., Litt, H., & Noël, P. B.: Impact of patient habitus and acquisition protocol on iodine quantification in dual source photon-counting CT. Journal of Medical Imaging (Bellingham) 11(Suppl 1): S12806, Dec 2024 Notes: doi: 10.1117/1.JMI.11.S1.S12806. Epub 2024 Jul 26.
1b1 Salazar, E., Liu, L. P., Perkins, A. E., Halliburton, S. S., Shapira, N., Litt, H. I., & Noël, P. B.: Impact of scatter radiation on spectral quantification performance of first- and second-generation dual-layer spectral computed tomography. Journal of Applied Clinical Medical Physics 25(7): e14383, Jul 2024 Notes: doi: 10.1002/acm2.14383. Epub 2024 May 27.
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Selected Publications
1b5 Sollmann, N., Mei, K., Löffler, M. T., Rühling, S., Beer, M., Zimmer, C., Kirschke, J., Noël, P. B., Baum, T., & Carballido-Gamio, J.: Simulated low-dose multi-detector computed tomography: spatial effects on surrogate parameters of bone strength at the proximal femur. Osteoporosis International 36(5): 917-928, May 2025 Notes: doi: 10.1007/s00198-025-07467-4.17e Im, J. Y., Micah, N., Perkins, A. E., Mei, K., Geagan, M., & Noël, P. B. : PixelPrint4D: A 3D printing method of fabricating patient-specific deformable CT phantoms for respiratory motion applications. Investigative Radiology Apr 2025 Notes: https://doi.org/10.1097/RLI.0000000000001182; Epub ahead of print.
1d4 Rosario-Berríos, D. N., Pang, A., Mossburg, K., Kim, J., Marrero, V. V., Yoon, S., Gupta, M., Lenz, O. C., Liu, L. P., Kian, A. C., Rivera, K. L., Shin, S., Noël, P. B., Lennon, E. M., & Cormode, D. P. : CT imaging of and therapy for inflammatory bowel disease via low molecular weight dextran coated ceria nanoparticles. Nanoscale 17(16): 10356-10370, Apr 2025 Notes: doi: 10.1039/d4nr04994b.
1bb Rosario-Berríos DN, Pang A, Liu LP, Maidment PSN, Kim J, Yoon S, Nieves LM, Mossburg KJ, Adezio A, Noël PB, Lennon EM, Cormode DP: The Effect of the Size of Gold Nanoparticle Contrast Agents on CT Imaging of the Gastrointestinal Tract and Inflammatory Bowel Disease. Bioconjug Chem 36(2): 233-244, Feb 2025 Notes: doi: 10.1021/acs.bioconjchem.4c00507. Epub 2025 Jan 9.
1c5 Rosario-Berrios, D. N., Pang, A., Liu, L., Maidment, P. S., Kim, J., Yoon, S., Nieves, L. M., Mossburg, K., Adezio, A., Noël, P. B., Lennon, E. M., & Cormode, D. P. : The effect of the size of gold nanoparticle contrast agents on CT imaging of the gastrointestinal tract and inflammatory bowel disease. Bioconjugate Chemistry Feb 2025 Notes: doi: 10.1021/acs.bioconjchem.4c00507.
16d Rybertt, M. V., Liu, L. P., Mathew, M., Sahbaee, P., Litt, H. I., & Noël, P. B.: Impact of Vessel Size, Dose Levels, and Body Habitus on Iodine Quantification in Cardiovascular Photon-Counting Computed Tomography. British Journal of Radiology 2025 Notes: https://doi.org/10.1093/bjr/tqaf181.
166 Sandvold, O. F., Proksa, R., Daerr, H., Perkins, A. E., Brown, K. M., Koehler, T., Manjeshwar, R.M. & Noël, P. B. : Efficient spectral data reduction for accurate iodine quantification in multi-energy CT. Scientific Reports 15, 2025 Notes: https://doi.org/10.1038/s41598-025-11270-w.
172 Liu, L. P., Pasyar, P., Liu, F., Cao, Q., Sandvold, O. F., Sahbaee, Shinohara, T., P., Litt, H. I., & Noël, P. B. : Assessing the Stability of Photon-Counting CT: Insights from a Two-Year Longitudinal Study. European Radiology Dec 2024 Notes: doi: 10.1007/s00330-024-11244-y. Epub ahead of print.
19d Liu, L. P., Pua, R., Dieckmeyer, M., Shapira, N., Sahbaee, P., Gang, G. J., Litt, H., & Noël, P. B.: Impact of patient habitus and acquisition protocol on iodine quantification in dual source photon-counting CT. Journal of Medical Imaging (Bellingham) 11(Suppl 1): S12806, Dec 2024 Notes: doi: 10.1117/1.JMI.11.S1.S12806. Epub 2024 Jul 26.
1b1 Salazar, E., Liu, L. P., Perkins, A. E., Halliburton, S. S., Shapira, N., Litt, H. I., & Noël, P. B.: Impact of scatter radiation on spectral quantification performance of first- and second-generation dual-layer spectral computed tomography. Journal of Applied Clinical Medical Physics 25(7): e14383, Jul 2024 Notes: doi: 10.1002/acm2.14383. Epub 2024 May 27.
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