Peter B. Noël, M.S., Ph.D.
Professor of Radiology
Chief Technology Officer (CTO), One Penn Radiology
Director of CT Research, Department of Radiology
Co-Director, Center for Imaging Research with Radiation in Radiology (CIR³), Department of Radiology
Director, Computed Tomography Center (CTC), Department of Radiology
Department: Radiology
Contact information
Hospital of the University of Pennsylvania
Department of Radiology
3400 Spruce Street, One Silverstein
Philadelphia, PA 19104
Department of Radiology
3400 Spruce Street, One Silverstein
Philadelphia, PA 19104
Publications
Links
Search PubMed for articles
Google Scholar
Laboratory for Advanced Computed Tomography Imaging
PixelPrint - lifelike computed tomography (CT) phantoms
Search PubMed for articles
Google Scholar
Laboratory for Advanced Computed Tomography Imaging
PixelPrint - lifelike computed tomography (CT) phantoms
Education
B. Eng. (Biomedical Engineering)
Technische Hochschule Mittelhessen, Gießen, Germany, 2003.
M. Eng. (Biomedical Engineering)
Technische Hochschule Mittelhessen, Gießen, Germany, 2004.
M.S. (Computer Science and Engineering)
University at Buffalo, The State University of New York, Buffalo, NY, United States, 2007.
Ph.D. (Computer Science and Engineering)
University at Buffalo, The State University of New York, Buffalo, NY, United States, 2009.
Permanent linkB. Eng. (Biomedical Engineering)
Technische Hochschule Mittelhessen, Gießen, Germany, 2003.
M. Eng. (Biomedical Engineering)
Technische Hochschule Mittelhessen, Gießen, Germany, 2004.
M.S. (Computer Science and Engineering)
University at Buffalo, The State University of New York, Buffalo, NY, United States, 2007.
Ph.D. (Computer Science and Engineering)
University at Buffalo, The State University of New York, Buffalo, NY, United States, 2009.
Description of Clinical Expertise
As Chief Technology Officer of One Penn Radiology, Dr. Noël oversees the department's technology strategy. His work spans governance and lifecycle planning for imaging platforms, interoperability across imaging modalities, and initiatives that improve operational efficiency. This operational perspective complements his research mission of translating imaging innovation into clinical practice.Description of Research Expertise
For more than a decade, Dr. Noël has directed a research program dedicated to advancing x-ray and computed tomography (CT) technology. A central theme of his work is the harmonization of hardware, software, image reconstruction, and post-processing into integrated clinical solutions. He has established a strong foundation for the clinical translation of novel diagnostic imaging technology, exemplified by his role in the introduction of photon-counting CT.In parallel, his team develops 3D-printed CT phantoms that serve as key tools for evaluation and standardization in clinical and research settings. Most recently, they introduced PixelPrint, a platform for fabricating patient-specific lung phantoms, which is now available to the broader research community.
Dr. Noël has authored more than 200 peer-reviewed publications in international journals and holds a patent portfolio spanning x-ray and CT imaging.
Selected Publications
Im, J. Y., Micah, N., Perkins, A. E., Mei, K., Geagan, M., & Noël, P. B. : PixelPrint4D: A 3D printing method of fabricating patient-specific deformable CT phantoms for respiratory motion applications. Investigative Radiology Page: 636-646, Oct 2025 Notes: https://doi.org/10.1097/RLI.0000000000001182.Liu, L. P., Pasyar, P., Liu, F., Cao, Q., Sandvold, O. F., Sahbaee, Shinohara, T., P., Litt, H. I., & Noël, P. B. : Assessing the Stability of Photon-Counting CT: Insights from a Two-Year Longitudinal Study. European Radiology 35(7): 3721-3728, Jul 2025 Notes: doi: 10.1007/s00330-024-11244-y. Epub 2024 Dec 19.
Liu, L. P., Pua, R., Rosario-Berrios, D. N., Sandvold, O. F., Perkins, A. E., Cormode, D. P., Shapira, N., Soulen, M., & Noël, P. B.: Reproducible spectral CT thermometry with liver-mimicking phantoms for image-guided thermal ablation. Physics in Medicine & Biology 69(4): 045009, Feb 2024 Notes: doi: 10.1088/1361-6560/ad2124.
Shapira, N., Donovan, K., Mei, K., Geagan, M., Roshkovan, L., Gang, G., Abed, M., Linna, N.,, Cranston, C., O'Leary, C., Dhanaliwala, A., Kontos, D., Litt, H.I., Stayman, J.W., Shinohara, R.T., & Noël, P. B. : PixelPrint: Three-dimensional printing of realistic patient-specific lung phantoms for validation of computed tomography post-processing and inference algorithms. PNAS Nexus 2(3): pgad026, Feb 2023 Notes: https://doi.org/10.1093/pnasnexus/pgad026.
Mei, K., Geagan, M., Roshkovan, L., Litt, H. I., Gang, G. J., Shapira, N., Stayman, W. J., & Noël, P. B.: Three-dimensional printing of patient-specific lung phantoms for CT imaging: Emulating lung tissue with accurate attenuation profiles and texture. Medical Physics 49(2): 825-835, Feb 2022 Notes: doi: 10.1002/mp.15407. Epub 2021 Dec 23.
Liu, L. P., Shapira, N., Sahbaee, P., Schnall, M., Litt, H. I., & Noël, P. B.: First-generation clinical dual-source photon-counting CT: ultra-low dose quantitative spectral imaging. European Radiology 32(12): 8579-8587, Dec 2022 Notes: doi: 10.1007/s00330-022-08933-x. Epub 2022 Jun 16.
Si-Mohamed, S., Tatard-Leitman, V., Laugerette, A., Sigovan, M., Pfeiffer, D., Rummeny, E. J., Coulon, P., Yagil, Y., Douek, P., Boussel, L. & Noël, P. B. : Spectral Photon-Counting Computed Tomography (SPCCT): in-vivo single-acquisition multi-phase liver imaging with a dual contrast agent protocol. Scientific Reports 9(1): 8458, June 2019 Notes: https://doi.org/10.1038/s41598-019-44821-z.
Willemink, M. J., & Noël, P. B. : The evolution of image reconstruction for CT-from filtered back projection to artificial intelligence. European Radiology 29(5): 2185-2195, Oct 2018 Notes: https://doi.org/10.1007/s00330-018-5810-7.
Mechlem, K., Ehn, S., Sellerer, T., Braig, E., Münzel, D., Pfeiffer, F., & Noël, P. B. : Joint Statistical Iterative Material Image Reconstruction for Spectral Computed Tomography Using a Semi-Empirical Forward Model. IEEE Transactions on Medical Imaging 37(1): 68-80, Jan 2018 Notes: https://doi.org/10.1109/TMI.2017.2726687.
Willer, K., Fingerle, A. A., Gromann, L., De Marco, F., Herzen, J., Achterhold, K., Gleich, B., Muenzel, D., Scherer, K. Renz, M., Renger, B., Kopp, F., Kriner, F., Fischer, F., Braun, C., Auweter, S., Hellbach, K., Reiser, M. F., Schroeter, T., Mohr, J., Yaroshenko, A., Maack, H.-I., Pralow, T., van der Heijden, H., Proksa, R., Koehler, T., Wieberneit, N., Rindt, K., Rummeny, E. J., Pfeiffer, F., & Noël, P. B.: X-ray dark-field imaging of the human lung-A feasibility study on a deceased body. Plos One 13(9): e0204565, September 2018 Notes: https://doi.org/10.1371/journal.pone.0204565.
Muenzel, D., Bar-Ness, D., Roessl, E., Blevis, I., Bartels, M., Fingerle, A. A., Ruschke, S., Coulon, P., Daerr, H., Kopp, F. K., Brendel, B., Thran, A., Rokni, M., Herzen, J., Boussel, L., Pfeiffer, F., Proksa, R., Rummeny, E. J., Douek, P., & Noël, P. B.: Spectral Photon-counting CT: Initial Experience with Dual-Contrast Agent K-Edge Colonography. Radiology 283(3): 723-728, Jun 2017 Notes: https://doi.org/10.1148/radiol.2016160890.