Peter B. Noël, M.S., Ph.D.

Assistant Professor of Radiology
Director of CT Research, Department of Radiology
Member, Penn Center for Musculoskeletal Disorders
Member, Institute for Translational Medicine and Therapeutics
Member, Center for Advanced Computed Tomography Imaging Services
Co - Director , Center for Imaging Research with Radiation in Radiology (CIR³)
Full Member, Abramson Cancer Center of the University of Pennsylvania
Department: Radiology
Contact information
Hospital of the University of Pennsylvania
Department of Radiology
3400 Spruce Street, One Silverstein
Philadelphia, PA 19104
Department of Radiology
3400 Spruce Street, One Silverstein
Philadelphia, PA 19104
Office: +1 (215) 898-8212
Publications
Education:
B. Eng. (Biomedical Engineering)
Technische Hochschule Mittelhessen, Gießen, Germany, 2003.
M. Eng. (Biomedical Engineering)
Technische Hochschule Mittelhessen, Gießen, Germany, 2004.
M.S. (Computer Science and Engineering)
University at Buffalo, The State University of New York, Buffalo, NY, United States, 2007.
Ph.D. (Computer Science and Engineering)
University at Buffalo, The State University of New York, Buffalo, NY, United States, 2009.
Permanent linkB. Eng. (Biomedical Engineering)
Technische Hochschule Mittelhessen, Gießen, Germany, 2003.
M. Eng. (Biomedical Engineering)
Technische Hochschule Mittelhessen, Gießen, Germany, 2004.
M.S. (Computer Science and Engineering)
University at Buffalo, The State University of New York, Buffalo, NY, United States, 2007.
Ph.D. (Computer Science and Engineering)
University at Buffalo, The State University of New York, Buffalo, NY, United States, 2009.
Description of Research Expertise
Dr. Noël’s primary research interests currently include spectral imaging with photon-counting detectors, advanced x-ray tube concepts, phase-contrast & darkfield imaging, reconstruction approaches, and the clinical translation of advanced technologies. His work has found application in oncology, pulmonary disease, cardiovascular disease, and osteoporosis screening. Dr. Noël’s publication record not only includes more than 175 peer-reviewed publications in international journals but also a patent portfolio in the areas of x-ray and CT imaging. He has been named to the editorial board of European Radiology for the medical physics section and is member of both national and international scientific organizations.Undergraduates and master's students, as well as prospective graduate students and postdoctoral fellows are encouraged to email Dr. Noël if interested in working in the Laboratory for Advanced Computed Tomography Imaging.
Selected Publications
Shapira, N., Donovan, K., Mei, K., Geagan, M., Roshkovan, L., Gang, G., Abed, M., Linna, N.,, Cranston, C., O'Leary, C., Dhanaliwala, A., Kontos, D., Litt, H.I., Stayman, J.W., Shinohara, R.T., & Noël, P. B. : PixelPrint: Three-dimensional printing of realistic patient-specific lung phantoms for validation of computed tomography post-processing and inference algorithms. PNAS Nexus 2023 Notes: https://doi.org/10.1093/pnasnexus/pgad026.Haghighi, B., Horng, H., Noël, P. B., Cohen, E., Pantalone, L., Vachani, A., ... & Kontos, D.: Radiomic phenotyping of the lung parenchyma in a lung cancer screening cohort. Scientific Reports 13(1), 2023 Notes: https://doi.org/10.1038/s41598-023-29058-1.
Liu, L. P., Hwang, M., Hung, M., Soulen, M. C., Schaer, T. P., Shapira, N., & Noël, P. B. : Accurate non-invasive mass and temperature quantifications with spectral CT. medRxiv 2022 Notes: https://doi.org/10.1101/2022.02.18.22271054.
Mei, K., Geagan, M., Roshkovan, L., Litt, H. I., Gang, G. J., Shapira, N., Stayman, W. J., & Noël, P. B.: Three‐dimensional printing of patient‐specific lung phantoms for CT imaging: Emulating lung tissue with accurate attenuation profiles and textures. Medical Physics 2022 Notes: https://doi.org/10.1002/mp.15407.
Liu, L. P., Shapira, N., Sahbaee, P., Schnall, M., Litt, H. I., & Noël, P. B.: First-generation clinical dual-source photon-counting CT: ultra-low dose quantitative spectral imaging. European Radiology 2022 Notes: https://doi.org/10.1007/s00330-022-08933-x.
Meyer, S., Liu, L. P., Litt, H. I., Halliburton, S. S., Shapira, N., & Noel, P. B.: Phantom-based quantification of the spectral accuracy in dual-layer spectral CT for pediatric imaging at 100 kVp. medRxiv 2022 Notes: https://doi.org/10.1101/2022.02.27.22271573.
Cuadros, A. P., Restrepo, C. M., Noël, P., & Arce, G. R.: Static coded illumination strategies for low-dose x-ray material decomposition. Applied Optics 2022 Notes: https://doi.org/10.1364/AO.446104.
Cao, W., Shapira, N., Maidment, A., Daerr, H., & Noël, P. B.: Hepatic dual-contrast CT imaging: slow triple kVp switching CT with CNN-based sinogram completion and material decomposition. Journal of Medical Imaging 2022 Notes: https://doi.org/10.1117/1.JMI.9.1.014003.
Horng, H., Singh, A., Yousefi, B., Cohen, E. A., Haghighi, B., Katz, S., Noël, P.B., Shinohara, R. T.,& Kontos, D. : Generalized ComBat harmonization methods for radiomic features with multi-modal distributions and multiple batch effects. Scientific Reports 2022 Notes: https://doi.org/10.1038/s41598-022-08412-9.
Luna, J. M., Barsky, A. R., Shinohara, R. T., Roshkovan, L., Hershman, M., Dreyfuss, A. D., Horng, H., Lou, C., Noël, P. B., Cengel, K. A., Katz, S., Diffenderfer, E. S., & Kontos, D.: Radiomic Phenotypes for Improving Early Prediction of Survival in Stage III Non-Small Cell Lung Cancer Adenocarcinoma after Chemoradiation. Cancers 2022 Notes: https://doi.org/10.3390/cancers14030700.