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Ramya Raghupathi, MD
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Associate Professor of Clinical Neurology
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Director, Clinical Competency Committee Penn
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Medical Director-Epilepsy Surgical program, Hospital of University of Pennsylvania
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Department: Neurology
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Contact information
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3400 Civic Center Boulevard, Pavilion 2nd Fl
Philadelphia, PA 19104
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Philadelphia, PA 19104
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Education:
21 9 M.D. 15 (Medicine) c
41 Tamil Nadu Dr.M.G.R. Medical University , 2009.
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Permanent link21 9 M.D. 15 (Medicine) c
41 Tamil Nadu Dr.M.G.R. Medical University , 2009.
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1c cortical stimulation
12 stereo EEG
32 Neuromodulation- VNS , RNS .DBS programming
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Description of Clinical Expertise
21 Epilepsy surgery1c cortical stimulation
12 stereo EEG
32 Neuromodulation- VNS , RNS .DBS programming
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1c4 James J Gugger 1, Catherine V Kulick-Soper 2, Nishant Sinha 2, Marc Jaskir 2, Peter N Hadar 3, Mariam Josyula 2, Nina Petillo 2, Ramya Raghupathi 2, Russell T Shinohara 4, Sandhitsu Das 2, Joel M Stein 5, Kathryn A Davis 2: Evaluation of limbic microstructural abnormalities in temporal lobe epilepsy: A neurite orientation distribution and density imaging study. Epilepsia 2025.
146 Ella Kole, B.S., Wajiha Yousuf, MD, Gabriela Bustamante RN MPH, Christina Boada, MD, Ramya Raghupathi, MD, Brian Emmert MD: Epilepsy Surgical Patients Report Subjective Improvement Regardless of Seizure Freedom Outcome One Year Post-Op. AAN poster 2025.
1db Zhou DJ, Woodson-Smith S, Emmert BE, Kornspun A, Larocque J, Kulick-Soper CV, Qiu MK, Ellis CA, Gugger JJ, Conrad EC, Waldman G, Ganguly T, Sinha SR, Davis KA, Stein JM, Liu GT, Gelfand M, Raghupathi R: Clinical characteristics and surgical outcomes of epilepsy associated with temporal encephalocele: A systematic review. Epilepsy Behav. 158(109928), Jul 2024 Notes: doi: 10.1016/j.yebeh.2024.109928.
1c2 Emmert BE, Xie K, Conrad EC, Ghosn NJ, Bauman K, Korzun J, Kulick-Soper CV, Naveed O, Hartmann N, LaRocque JJ, Mindy Ganguly T, Gugger JJ, Raghupathi R, Gelfand MA, Davis KA, Sinha SR, Litt B, Shinohara RT, Ellis CA.: Alcohol for seizure induction in the epilepsy monitoring unit. Epilepsy Behav 150(109572), Jan 2024 Notes: doi: 10.1016/j.yebeh.2023.109572. Epub 2023 Dec 8.
169 Jae Kim M, Schaper F, Rouhl R, Temel Yasin, Fox M, Davis K, Isaac Chen H, Raghupathi R, Kang JY, Anderson W.: Common Network for Laser Interstitial Thermal Therapy and Thalamic DBS for Temporal Lobe Epilepsy Organization for Human Brain Mapping (OHBM) 2024 Notes: abstract presentation.
fd Gabriela Bustamanta, Ramya Raghupathi: Evaluating the Usefulness of Neuromodulation-Specific Surgical Outcome Scales in Patients with Deep Brain Stimulation (DBS). AES poster 2024.
15e Qiu L, Pomeraniec IJ, Raghupathi R, Isaac Chen H, Digiovine M P, Catenaccio E, Kennedy B, Halpern C.: Magnetic resonance-guided focused ultrasound for the treatment of hypothalamic hamartomas FUN (focused USG and Neuromodulation conference) 2024 Notes: abstract presentation.
173 Michalak AJ, Greenblatt A, Wu S, Tobochnik S, Dave H, Raghupathi R, Esengul YT, Guerra A, Tao JX, Issa NP, Cosgrove GR, Lega B, Warnke P, Chen HI, Lucas T, Sheth SA, Banks GP, Kwon CS, Feldstein N, Youngerman B, McKhann G, Davis KA, Schevon CA.: Seizure onset patterns predict outcome after stereoelectroencephalography- 81 guided laser amygdalohippocampotomy. Epilepsia 64 (6): 1568-1581, Jun 2023 Notes: doi: 10.1111/epi.17602.
186 Cornblath EJ, Lucas A, Armstrong C, Greenblatt AS, Stein JM, Hadar PN, Raghupathi R, Marsh E, Litt B, Davis KA, Conrad EC. : Quantifying trial-by-trial variability during cortico-cortical evoked potential mapping of epileptogenic tissue. Epilepsia. Epilepsia, 64(4): 1021-1034, Apr 2023 Notes: doi: 10.1111/epi.17528.
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Selected Publications
25f Amy J Halliday 1 2, Lisa Gillinder 3 4, Alan Lai 2, Udaya Seneviratne 2 5, Holly Fontenot 6, Tracy Cameron 6, Karen McLean 6, Andrew Niemiec 6, Ramya Raghupathi 7, Taneeta M Ganguly 7, Colin Ellis 7, Erin C Conrad 7, Robert Briggs 8, Kristian Bulluss 9, Patrick Kwan 10 11 12, Piero Perucca 13, Terence J O'Brien 10 11 12, Aileen McGonigal 3 14, Matthew Gutman 11 15, Jason Papacostas 16, Michael W K Fong 17, Andrew Lee 18, Douglas E Crompton 19, Joshua Laing 10, Manori Wijayath 20, Andrew P Morokoff 21, Michael Murphy 22, Wendyl J D'Souza 1, Mark J Cook 1 2 6 ac : The UMPIRE study: A first-in-human multicenter trial of bilateral subscalp monitoring for epileptic seizure detection. Epilepsia May 2025.1c4 James J Gugger 1, Catherine V Kulick-Soper 2, Nishant Sinha 2, Marc Jaskir 2, Peter N Hadar 3, Mariam Josyula 2, Nina Petillo 2, Ramya Raghupathi 2, Russell T Shinohara 4, Sandhitsu Das 2, Joel M Stein 5, Kathryn A Davis 2: Evaluation of limbic microstructural abnormalities in temporal lobe epilepsy: A neurite orientation distribution and density imaging study. Epilepsia 2025.
146 Ella Kole, B.S., Wajiha Yousuf, MD, Gabriela Bustamante RN MPH, Christina Boada, MD, Ramya Raghupathi, MD, Brian Emmert MD: Epilepsy Surgical Patients Report Subjective Improvement Regardless of Seizure Freedom Outcome One Year Post-Op. AAN poster 2025.
1db Zhou DJ, Woodson-Smith S, Emmert BE, Kornspun A, Larocque J, Kulick-Soper CV, Qiu MK, Ellis CA, Gugger JJ, Conrad EC, Waldman G, Ganguly T, Sinha SR, Davis KA, Stein JM, Liu GT, Gelfand M, Raghupathi R: Clinical characteristics and surgical outcomes of epilepsy associated with temporal encephalocele: A systematic review. Epilepsy Behav. 158(109928), Jul 2024 Notes: doi: 10.1016/j.yebeh.2024.109928.
1c2 Emmert BE, Xie K, Conrad EC, Ghosn NJ, Bauman K, Korzun J, Kulick-Soper CV, Naveed O, Hartmann N, LaRocque JJ, Mindy Ganguly T, Gugger JJ, Raghupathi R, Gelfand MA, Davis KA, Sinha SR, Litt B, Shinohara RT, Ellis CA.: Alcohol for seizure induction in the epilepsy monitoring unit. Epilepsy Behav 150(109572), Jan 2024 Notes: doi: 10.1016/j.yebeh.2023.109572. Epub 2023 Dec 8.
169 Jae Kim M, Schaper F, Rouhl R, Temel Yasin, Fox M, Davis K, Isaac Chen H, Raghupathi R, Kang JY, Anderson W.: Common Network for Laser Interstitial Thermal Therapy and Thalamic DBS for Temporal Lobe Epilepsy Organization for Human Brain Mapping (OHBM) 2024 Notes: abstract presentation.
fd Gabriela Bustamanta, Ramya Raghupathi: Evaluating the Usefulness of Neuromodulation-Specific Surgical Outcome Scales in Patients with Deep Brain Stimulation (DBS). AES poster 2024.
15e Qiu L, Pomeraniec IJ, Raghupathi R, Isaac Chen H, Digiovine M P, Catenaccio E, Kennedy B, Halpern C.: Magnetic resonance-guided focused ultrasound for the treatment of hypothalamic hamartomas FUN (focused USG and Neuromodulation conference) 2024 Notes: abstract presentation.
173 Michalak AJ, Greenblatt A, Wu S, Tobochnik S, Dave H, Raghupathi R, Esengul YT, Guerra A, Tao JX, Issa NP, Cosgrove GR, Lega B, Warnke P, Chen HI, Lucas T, Sheth SA, Banks GP, Kwon CS, Feldstein N, Youngerman B, McKhann G, Davis KA, Schevon CA.: Seizure onset patterns predict outcome after stereoelectroencephalography- 81 guided laser amygdalohippocampotomy. Epilepsia 64 (6): 1568-1581, Jun 2023 Notes: doi: 10.1111/epi.17602.
186 Cornblath EJ, Lucas A, Armstrong C, Greenblatt AS, Stein JM, Hadar PN, Raghupathi R, Marsh E, Litt B, Davis KA, Conrad EC. : Quantifying trial-by-trial variability during cortico-cortical evoked potential mapping of epileptogenic tissue. Epilepsia. Epilepsia, 64(4): 1021-1034, Apr 2023 Notes: doi: 10.1111/epi.17528.
2c