Keith W Pratz, MD
Associate Professor of Medicine (Hematology-Oncology) at the Hospital of the University of Pennsylvania
Attending Physician, Hospital of the University of Pennsylvania
Director, Leukemia Programs, University of Pennsylvania/Abramson Cancer Center
Section Chief Leukemia, University of Pennyslvania
Department: Medicine
Contact information
3400 Civic Center Blvd.
South Pavilion Room 12-155
Philadelphia, PA 19104
South Pavilion Room 12-155
Philadelphia, PA 19104
Education:
BS (Molecular Biology)
University of Maryland at College Park, 1998.
MD (Medicine )
University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, 2002.
Permanent linkBS (Molecular Biology)
University of Maryland at College Park, 1998.
MD (Medicine )
University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, 2002.
Description of Clinical Expertise
Hematologic Malignancies, Leukemia, Myelodysplastic Syndrome, Myeloproliferative Disorders, MDS, AML, ALL, CML, bone Marrow TransplantDescription of Research Expertise
Leukemia, Myelodysplastic Syndrome, Myeloproliferative Disorders, MDS, AML, ALL, CMLSelected Publications
Bhavana Bhatnagar, Zhuoxin Sun, Ryan Mattison, Elisabeth Paietta, Yanming Zhang, Janis Racevskis, Hillard Lazarus, Jacob Rowe, Daniel Arber, Matthew Wieduwilt, Michaela Liedtke, Julie Bergeron, Brent Wood, Keith Pratz, Shira Dinner, Noelle Frey, Steven Gore, Ehab Atallah, Geoffrey Uy, Deepa Jeyakumar, Tara Lin, Cheryl Willman, Nikolai Podoltsev, Daniel Deangelo, Shejal Patel, Michelle Elliott, Anjali Advani, Dimitrios Tzachanis, Pankit Vachhani, Rupali Roy, Elad Sharon, Richard Little, Harry Erba, Richard Stone, Selina Luger, Charles Mullighan, Martin Tallman, Mark Litzow: Impact of therapy delays on outcomes in adults with BCR:: ABL1 negative b-lineage acute lymphoblastic leukemia (ALL) in the ECOG-ACRIN E1910 trial randomized to conventional chemotherapy+/-blinatumomab. Blood 146, Dec 2025 Notes: ASH annual meeting abstract.Anjali Advani, Li Chen, Zhuoxin Sun, Ryan Mattison, Elisabeth Paietta, Yanming Zhang, Janis Racevskis, Hillard Lazarus, Jacob Rowe, Dan Arber, Matthew Wieduwilt, Michaela Liedtke, Julie Bergeron, Brent Wood, Keith Pratz, Shira Dinner, Noelle Frey, Steven Gore, Bhavana Bhatnagar, Ehab Atallah, Geoffrey Uy, Deepa Jeyakumar, Tara Lin, Cheryl Willman, Nikolai Podoltsev, Daniel Deangelo, Shejal Patel, Michelle Elliott, Dimitrios Tzachanis, Pankit Vachhani, Rupali Bhave, Elad Sharon, Richard Little, Harry Erba, Richard Stone, Selina Luger, Charles Mullighan, Martin Tallman, Mark Litzow: Toxicities on the E1910 phase III randomized trial of blinatumomab plus chemotherapy in adults with BCR: ABL-1 negative acute lymphoblastic leukemia. Blood 146, Dec 2025 Notes: ASH annual meeting abstract.
James Foran, Li Chen, Selina Luger, Zhuoxin Sun, Heidi Klepin, Catherine Lai, David Claxton, Hillard Lazarus, Daniel Arber, Jacob Rowe, Elisabeth Paietta, Janis Racevskis, Francine Garrett-Bakelman, Yanming Zhang, Jessica Altman, Aref Al-Kali, Hong Zheng, Keith Pratz, Kristen O'Dwyer, Edward Broun, Bayard Powell, John Godwin, Yishai Ofran, Efrat Dotan, Mark Litzow, Martin Tallman, Lynne Wagner: Prospective study of patient-reported depression, and cognitive and functional impairment, and impact on survival and induction mortality in fit adults age≥ 60 years receiving intensive chemotherapy (IC) for Acute Myeloid Leukemia (AML): Prospective geriatric assessment (GA) report from ECOG-ACRIN (EA) E2906 randomized study. Blood 146, Dec 2025 Notes: ASH annual meeting abstract.
Gail Roboz, Eunice Wang, Amir Fathi, Harry Erba, Keith Pratz, Guru Subramanian Guru Murthy, Leonard Alsfeld, James Blachly, Kiran Naqvi, Ghayas Issa, Ayman Qasrawi, Stephen Strickland, Neil Palmisiano, Jessica Altman, Cecilia Arana Yi, Grerk Sutamtewagul, Yazan Madanat, Suresh Kumar Balasubramanian, Christine McMahon, Hongling Zhang, Tianle Chen, Marcie Riches, Daniel Corum, Mollie Leoni, Amer Zeidan: Ziftomenib in combination with venetoclax and azacitidine in newly diagnosed NPM1-m acute myeloid leukemia: Phase 1b results from KOMET-007. Blood 146, Dec 2025 Notes: ASH annual meeting Abstract.
Matthew Connor, Wei-Ting Hwang, Saar Gill, Alexander Perl, Ximena Jordan Bruno, Nasheed Hossain, Catherine Lai, Alison Loren, Selina Luger, Andrew Matthews, Shannon McCurdy, Pashna Munshi, Keith Pratz, Amanda Cervini, Jean McConville, Joanne Shea, Charles Tongue, Heather Difilippo, Jacob Kesselman, Amy Marshall, Megan Four, Shannon Christensen, Vanessa Gonzalez, Julie Jadlowsky, Gabriela Plesa, Don Siegel, Rachel Leskowitz, Joseph Fraietta, Bruce Levine, David Porter, Elizabeth Hexner, Carl June, Jakub Svoboda, Noelle Frey: IL18-armored CAR T cells in relapsed/refractory B cell acute lymphoblastic leukemia. Blood 146, Dec 2025 Notes: ASH annual Meeting Abstract.
Xiaoming Zhong, Kathryn Roberts, Lindsey Montefiori, Zhuoxin Sun, Huimei Wei, Petri Polonen, Ti-Cheng Chang, Wenchao Zhang, Shaohua Lei, Evadnie Rampersaud, Yiping Fan, Gang Wu, Ryan Mattison, Yanming Zhang, Janis Racevskis, Hillard Lazarus, Jacob Rowe, Daniel Arber, Matthew Wieduwilt, Michaela Liedtke, Julie Bergeron, Brent Wood, Keith Pratz, Shira Dinner, Noelle Frey, Steven Gore, Bhavana Bhatnagar, Ehab Atallah, Geoffrey Uy, Deepa Jeyakumar, Tara Lin, Cheryl Willman, Nikolai Podoltsev, Daniel Deangelo, Shejal Patel, Michelle Elliott, Anjali Advani, Dimitrios Tzachanis, Pankit Vachhani, Rupali Roy, Elad Sharon, Richard Little, Harry Erba, Richard Stone, Martin Tallman, Jun J Yang, Elisabeth Paietta, Selina Luger, Mark Litzow, Charles Mullighan: Genomic determinants of treatment outcome and identification of a new genomic subset of adult acute lymphoblastic leukemia from the ECOG-ACRIN E1910 randomized phase III trial. Blood 146, Dec 2025 Notes: ASH annual Meeting abstract.
Catherine Lai, Thomas Greenwood, E Paul Wileyto, Nisha Singh, Ashlena Livingston, Amanda Lopez, Selina Luger, Alexander Perl, Ximena Jordan Bruno, Elizabeth Hexner, Shannon McCurdy, Saar Gill, Gary Okano, Ali McBride, Carmelo Alonso, Keith Pratz: Age-ing study: A prospective evaluation of geriatric, patient-reported and frailty assessments to predict outcomes in older adults with acute myeloid leukemia. Blood 146, Dec 2025 Notes: ASH annual Meeting Abstract.
Eytan Stein, Courtney DiNardo, Amir Fathi, Alice Mims, Keith Pratz, Michael Savona, Anthony Selwyn Stein, Richard Stone, Eric Winer, Christopher Seet, Hartmut Döhner, Dan Pollyea, James McCloskey, Olatoyosi Odenike, Bob Lowenberg, Gert J Ossenkoppele, Mikhail Roshal, Sung Choe, Qian Meng, Stephanie Kapsalis, Prapti Patel, Hagop Kantarjian, Martin Tallman: Updated response and safety analyses from a Phase 1 study of ivosidenib combined with intensive chemotherapy in patients with newly diagnosed (ND) Acute Myeloid Leukemia with isocitrate dehydrogenase (IDH) 1 mutation. Blood 146, Dec 2025 Notes: ASH annual meeting Abstract.
Ghayas Issa, Amir Fathi, Amer Zeidan, Harry Erba, Gail Roboz, Jessica Altman, Keith Pratz, Mark Juckett, Tara Lin, Suresh Kumar Balasubramanian, Anjali Advani, Gary Schiller, Neil Palmisiano, Marcello Rotta, Stephen Strickland, Christine McMahon, Yazan Madanat, Talha Badar, Mohamad Khawandanah, George Yaghmour, James McCloskey, James Mangan, Antoine Saliba, Ivana Gojo, Diaa Osman, Hongling Zhang, Ying Tian, Marcie Riches, Daniel Corum, Mollie Leoni, Eunice Wang: Ziftomenib in combination with venetoclax and azacitidine in relapsed/refractory NPM1-m or KMT2A-r acute myeloid leukemia: Updated phase 1a/b safety and clinical activity results from KOMET-007. Blood ASH annual meeting Abstract, 146, Dec 2025.
Shira Dinner, Zhuoxin Sun, Elisabeth Paietta, Ryan Mattison, Kathryn Roberts, Yanming Zhang, Janis Racevskis, Hillard Lazarus, Jacob Rowe, Daniel Arber, Matthew Wieduwilt, Michaela Liedtke, Julie Bergeron, Brent Wood, Yaqi Zhao,Gang Wu, Ti-Cheng Chang, Wenchao Zhang, Keith Pratz, Noelle Frey, Steven Gore, Bhavana Bhatnagar, Ehab Atallah, Geoffrey Uy, Deepa Jeyakumar, Tara Lin, Cheryl Willman, Nikolai Podoltsev, Daniel DeAngelo, Shejal Patel, Michelle Elliott, Anjali Advani, Dimitrios Tzachanis, Pankit Vachhani, Rupali Roy Bhave, Elad Sharon, Richard Little, Harry Erba, Richard Stone, Charles Mullighan, Martin Tallman, Selina Luger, Mark Litzow: Addition of Blinatumomab to Consolidation Therapy For Younger Adults (BCR:ABL1-NEGATIVE B-ACUTE LYMPHOBLASTIC LEUKEMIA (ALL)) on The ECOG-ACRIN E1910 Phase III Trial. HemaSphere - European Hematology Association Annual meeting 9(1): 26, June 2025.