Christopher Brown, MD, PhD

Instructor A of Neurology
Instructor in Neurology, University of Pennsylvania
Department: Neurology
Contact information
Publications
Education:
B.A. (Biology-Neuroscience)
Washington University in St. Louis, 2011.
Ph.D. (Anatomy and Neurobiology)
University of Kentucky, 2017.
M.D.
University of Kentucky, 2019.
Permanent linkB.A. (Biology-Neuroscience)
Washington University in St. Louis, 2011.
Ph.D. (Anatomy and Neurobiology)
University of Kentucky, 2017.
M.D.
University of Kentucky, 2019.
Selected Publications
Taghvaei M, Cook P, Sadaghiani S, Shakibajahromi B, Tackett W, Dolui S, De D, Brown C, Khandelwal P, Yushkevich P, Das S, Wolk DA, Detre JA.: Young versus older subject diffusion magnetic resonance imaging data for virtual white matter lesion tractography. Hum Brain Mapp 2023.Bauer CE, Brown CA, Gold BT; Alzheimer's Disease Neuroimaging Initiative.: Education does not protect cognitive function from brain pathology in the ADNI 2 cohort. Neurobiol Aging 2020.
Brown CA, Schmitt FA, Smith CD, Gold BT.: Distinct patterns of default mode and executive control network circuitry contribute to present and future executive function in older adults. Neuroimage 195: 320-332, Jul 2019.
Brown CA, Jiang Y, Smith CD, Gold BT.: Age and Alzheimer's pathology disrupt default mode network functioning via alterations in white matter microstructure but not hyperintensities. Cortex 2018.
Al-Janabi OM, Brown CA, Bahrani AA, Abner EL, Barber JM, Gold BT, Goldstein LB, Murphy RR, Nelson PT, Johnson NF, Shaw LM, Smith CD, Trojanowski JQ, Wilcock DM, Jicha GA.: Distinct White Matter Changes Associated with Cerebrospinal Fluid Amyloid-β1-42 and Hypertension. J Alzheimers Dis 2018.
Gold BT, Brown CA, Hakun JG, Shaw LM, Trojanowski JQ, Smith CD.: Clinically silent Alzheimer's and vascular pathologies influence brain networks supporting executive function in healthy older adults. Neurobiol Aging 2017.
Brown CA, Johnson NF, Anderson-Mooney AJ, Jicha GA, Shaw LM, Trojanowski JQ, Van Eldik LJ, Schmitt FA, Smith CD, Gold BT.: Development, validation and application of a new fornix template for studies of aging and preclinical Alzheimer's disease. Neuroimage Clin 13: 106-115, Nov 2016.
Brown CA, Hakun JG, Zhu Z, Johnson NF, Gold BT.: White matter microstructure contributes to age-related declines in task-induced deactivation of the default mode network. Front Aging Neurosci 7: 194, Oct 2015.
Hakun JG, Zhu Z, Brown CA, Johnson NF, Gold BT.: Longitudinal alterations to brain function, structure, and cognitive performance in healthy older adults: A fMRI-DTI study. Neuropsychologia 2015.
Tian L, Karimi M, Brown CA, Loftin SK, Perlmutter JS.: In vivo measures of nigrostriatal neuronal response to unilateral MPTP treatment. Brain Res 1571: 49-60, Jul 2014.