Aaron Rothstein, MD

faculty photo
Assistant Professor of Neurology at the Hospital of the University of Pennsylvania
PI for Promoting Recovery After Stroke with Amantadine (PRESTA) trial, University of Pennsylvania
Site PI for cAPPricorn-1, University of Pennsylvania
Co-I NIH StrokeNet, University of Pennsylvania
Independent Medical Monitor for MyStroke, University of Pennsylvania
Site PI for DISCOVERY, University of Pennsylvania
Site PI for MCAD-Stroke, University of Pennsylvania
Site PI for SATURN, Virtua Our Lady of Lourdes
Department: Neurology

Contact information
3400 Spruce St
Philadelphia, PA 19147
Education
BA (History-PreMed)
Yale University, 2009.
MD (Doctor of Medicine)
Wake Forest School of Medicine, 2015.
MS (Epidemiology)
University of Pennsylvania, 2022.
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Selected Publications

Goicoechea EB, Ellsworth P, Siegler JE, Brorson JR, Lineback CM, Conyers FG, Kerrigan D, Eklund K, Yaghi S, Khasiyev F, Melkumova E, Culbertson CJ, D'Souza M, Jillella DV, Glover P, Aboul-Nour H, Nahab F, Shahrivari M, Nedelcu S, Liebeskind DS, Smith MM, Rothstein A, Bowman A, Zha A, Kala N, Abu Qdais A, Al Kasab S, Farooqui M, Rojas-Soto D, Aziz Y, Herpich F, Daniel JP, Thompson SL, Patel V, Nguyen TN, Sehgal S, Yu W, Kam W, Van Coevering R, Dumitrascu OM, Alvi M, Krishnaiah B, Salehi Omran S, Linares G, Singh E, Ali H, Penckofer M, Thon JM, Mannion S, Chahien D, Chen L, Talat F, Abbasi M, Sharma R.: Anticoagulation Treatment Response Among Phenotypic ESUS Clusters: Evidence From CASPR. Ann Clin Transl Neurol Oct 2026.

Penckofer M, Siegler J, Goldstein ED, Murphy K, Smith M, Bowman A, Nahab F, Daniel JP, Stretz C, Mannion S, Gaudio E, Thacker Q, Nelson A, Sathya A, Kam W, Kang J, Ro J, Thompson SL, Glover P, Sehgal S, Conyers FG, Xi R, Sarkar M, Melkumova E, Abburi N, Rothstein A, Thottempudi N, Sharma R, Aboul-Nour H, Chen L, Farooqui M, Rozental SF, Dumitrascu OM, Sharief A, Kerrigan DLG, Almallouhi E, Al-Kasab S, Chionatos RA, Peshwe K, Luan C, Doolittle C, Lineback CM, Valhuerdi Porto C, Stamm B, Kala N, Nguyen T, Linares G, Khezri N, Zubair AS, Nedelcu S, Yaghi S, Van Coevering RJ, Eklund K, Khasiyev F, Herpich F, Brorson JR, Thon JM.: Association Between Insurance Status on Risk of Stroke Recurrence with Incident Cryptogenic Stroke: A Secondary Analysis of the Cardiac Abnormalities in Stroke Prevention and Recurrence Study. Neuroepidemiology Aug 2026.

Rosa SDB, Soares M, Nunes AP, Shu L, Wu E, Henninger N, Muppa J, Heldner MR, Antonenko K, Omran S, Nehme A, Rothstein A, Khazaal O, Metanis I, Leker RR, Ghannam M, Rioux B, Romoli M, Zedde M, Pascarella R, Kam W, Grory BM, Velez F, Penckofer M, Siegler J, Zubair AS, Marto JP, Krupka D, Elnazair M, Yaghi S, Aguiar de Sousa D.: Cervical artery dissection after upper respiratory infection: clinical features and prognosis. Acta Neurol Belg Aug 2026.

Rothstein A, Andres W, Abbruzzese S, Stulberg E, Law CA, Murthy S, Kamel H, Sloane KL, Schneider ALC.: Trends in Vascular Risk Factor Control Among US Adults With Prior Stroke: 1999 to 2023. J Am Heart Assoc 15: e046500, May 2026.

Sarraj A, Thomalla G, Yoshimura S, Huo X, Costalat V, Zaidat OO, Arquizan C, Johns H, Yogendrakumar V, Churilov L, Pujara D, Sitton CW, Liebeskind DS, Inoue M, Majoie C, Beenen L, Abdulrazzak MA, Chaturvedi A, Singh S, Parsons MW, Denis A, Sakai N, Nguyen TN, Albucher JF, Kasab SA, Hassan AE, Abraham M, Rai A, Henon H, Sun D, Yamagami H, Subtil F, Bonekamp S, Uchida K, Yuan G, Gory B, Smith W, Ortega-Gutierrez S, Blackburn S, Sheth SA, Marnat G, Liu L, Shirakawa M, Fiehler J, Jensen M, Shindo S, Nogueira RG, Grandhi R, Jabbour P, Hussain MS, Dippel D, Wang Y, Yazawa Y, Simonsen CZ, Wang Y, Chen M, Hill MD, Grotta JC, Lapergue B, Jovin TG, Yoo AJ, Bendszus M, Campbell BCV, Morimoto T, Miao Z; ATLAS Investigators.: Endovascular thrombectomy for patients with large-core ischaemic stroke presenting up to 24 h after onset (ATLAS): a systematic review and individual patient data meta-analysis with central imaging adjudication. Lancet May 2026.

Bakradze E, Shu L, Yaghi S, Tran TLN, Crandal RC, Lester E, Mandel DM, Siegler JE, Penckofer M, Liberman AL, Field TS, Khan F, Kam W, Mac Grory B, Saleh Velez FG, Henninger N, Elangovan C, Krishnaiah B, Gandhi P, Shahripour RB, Ghannam M, Heldner MR, Antonenko K, Rothstein A, Leker RR, Metanis I, Samaniego E, Romoli M, Zedde M, Pascarella R, Nguyen TN, Klein P, Khasiyev F, Khazaal O, Almajali M, Zubair AS, Elnazeir M, Marto JP, Nehme A, Giles JA, Engelter ST, Stretz C, Salehi Omran S.: Possible Diagnostic Error in Cervical Artery Dissection: Analysis of STOP-CAD Study. J Am Heart Assoc May 2026.

Sharma R, McNamara KF, Badillo Goicoechea E, Bowman A, Van Coevering R, Chen L, Penckofer M, Singh E, Kerrigan D, Aboul-Nour H, Nahab F, Glover P, Krishnaiah B, Yaghi S, Khasiyev F, Lineback C, Melkumova E, Culbertson C, Nguyen TN, Thompson SL, Jillella D, Daniel JA, Aziz Y, Alvi M, Herpich F, Shahrivari M, Chionatos RA, Elangovan C, Kang J, Zha A, Farooqui M, Rothstein A, Khan F, Smith M, Brown S, Abu Qdais A, Liebeskind DS, Abburi N, Rozental S, Nedelcu S, Thon JM, Stretz C, Thottempudi N, Yu W, Eklund K, Linares G, de Havenon A, Siegler JE.: Recurrent Stroke in Patients With Cryptogenic Stroke and Left Ventricular Injury: The Cardiac Abnormalities in Stroke Prevention and Recurrence (CASPR) Study. Stroke Mar 2026.

Muhammad Aemaz Ur Rehman, Farhan Khan, Shadi Yaghi, Sami Al Kasab, Ahmad Abu Qdais, Sridhara Yaddanapudi, Sabiha Sultana, Muhib Khan, Maarij Malik, James Klaas, Christopher Leon Guerrero, Faddi Saleh Velez, Cameron Owens, Camila Pinto, Margy McCullough-Hicks, Dawson Cooper, Abhiram Parameswaran Pillai, Praveen Hariharan, Shaista Alam, Mirjam Heldner, Kateryna Antonenko, William Almiri, Aaron Rothstein, Balaji Krishnaiah, Cheran Elangovan, Ayush Agarwal, Michele Romoli, Marrone Nicola, Stefano Vozzi, Malik Ghannam, Mahmoud Dibas, Joao Pedro Marto, Mohammad AlMajali, Alexis Simpkins, Diana Aguiar De Sousa, Mafalda Soares, Amanda Lima, James Siegler, Argyro Tountopoulou, SOFIA Vasilopoulou, Adam de Havenon, Nils Henninger, Johanna Helenius, Mohammad Khasawneh, Piers Klein, Liqi Shu, Pooja Khatri, Thanh Nguyen, David Liebeskind, Ekaterina Bakradze: Dual Antiplatelet versus Anticoagulant-Plus-Antiplatelet Therapy in Symptomatic Intracranial Atherosclerosis: A Multicenter Comparative Study. International Stroke Conference February 2026.

Setareh Salehi Omran, Liqi Shu, Shadi Yaghi, Christian Sidebottom, Ross Crandall, Evan Lester, Conner Lee, Nils Henninger, Jayachandra Muppa, Muhammed Gunduz, Mirjam Heldner, Kateryna Antonenko, Ahmad Nehme, Muhib Khan, Dania Mallick, Aaron Rothstein, Ossama Khazaal, Josefin Emelie Kaufmann, Stefan Engelter, Christopher Traenka, Preet Gandhi, Issa Metanis, Ronen Leker, Regina von Rennenberg, Reza Bavarsad Shahripour, Xiaofan Guo, Malik Ghannam, Mohammad AlMajali, Edgar Samaniego, Ana Fonseca, Diana Cruz, Michele Romoli, Zafer Keser, Marialuisa Zedde, Brian Mac Grory, Ekaterina Bakradze, Faddi Saleh Velez, Mary Penckofer, James Siegler, Joshua Willey, Adeel Zubair, Joao Pedro Marto, Piers Klein, Thanh Nguyen, Farid Khasiyev, Alexis Simpkins, Marwa Elnazeir, Balaji Krishnaiah, Cheran Elangovan: Young Adults with Cervical Artery Dissection have a Distinct Clinical Phenotype: A Post-Hoc Analysis of the STOP-CAD Study. International Stroke Conference February 2026.

Pargol Balali, Baris Alten, Banafsheh Shakibajahromi, Shenghua Zhu, Yu Sakai, Sriharsha Voleti, Konstanze Guggenberger, Aaron Rothstein, Brooks Applewhite, Jae Song, Steven Messe, Scott Kasner: Morphologic Features of Carotid Webs and Risk of Ischemic Stroke. International Stroke Conference February 2026.

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Last updated: 10/08/2026
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