Tristan Hayeck, PhD

faculty photo
Research Assistant Professor of Pathology and Laboratory Medicine
Department: Pathology and Laboratory Medicine

Contact information
Abramson Research Bldg. 710B
The Children's Hospital of Philadelphia
3615 Civic Center Blvd.
Philadelphia, PA 19104
Office: 267-426-7588
Education:
B.S. (Mechanical Engineering)
Massachusetts Institute of Technology, 2006.
M.S. (Biostatistics,)
Harvard T. H. Chan School of Public Health, 2012.
Ph.D. (Biostatistics)
Harvard T. H. Chan School of Public Health, 2015.
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Selected Publications

Hayeck T.J., Li Y., Mosbruger T.L., Bradfield J.P., Gleason A.G., Damianos G., G.T. Shaw, Duke J.L., Conlin L.K., Turner T.N., Fernandez-Vina M.A., Sarmady M. and Monos, D.S.: Improved detection of evolutionary selection highlights potential bias from different sequencing strategies in complex genomic-regions. bioRxiv May 2022 Notes: https://doi.org/10.1101/2021.09.28.462165.

Hayeck, T.J., Stong, N., Baugh, E., Dhindsa, R., Turner, T.N., Malakar, A., Mosbruger, T.L., Duan, Y., Ionita-Laza, I., Goldstein, D. and Allen, A.S: Ancestry adjustment improves genome-wide estimates of regional intolerance. Genetics 221(2): iyac050, Apr 2022 Notes: doi: 10.1093/genetics/iyac050.

Shieh M, *Hayeck TJ, Dinh A, Duke JL, Chitnis N, Mosbruger T, Morlen RP, Ferriola D, Kneib C, Hu T, Huang Y, Monos DS : Complex Linkage Disequilibrium Effects in HLA-DPB1 Expression and Molecular Mismatch Analyses of Transplantation Outcomes. Transplantation 105(3): 637-647, March 2021.

Padhi EM, Hayeck TJ, Cheng Z, Chatterjee S, Mannion BJ, Byrska-Bishop M, Willems M, Pinson L, Redon S, Benech C, Uguen K, Audebert-Bellanger S, Le Marechal C, Férec C, Efthymiou S, Rahman F, Maqbool S, Maroofian R, Houlden H, Musunuri R, Narzisi G, Abhyankar A, Hunter RD, Akiyama J, Fries LE, Ng JK, Mehinovic E, Stong N, Allen AS, Dickel DE, Bernier RA, Gorkin DU, Pennacchio LA, Zody MC, Turner TN: Coding and noncoding variants in EBF3 are involved in HADDS and simplex autism. Hum Genomics 15(1): 44, 2021.

Hayeck, T. J., Stong, N., Wolock, C. J., Copeland, B., Kamalakaran, S., Goldstein, D.B., & Allen, A. S: Improved Pathogenic Variant Localization via a Hierarchical Model of Sub-regional Intolerance. The American Journal of Human Genetics 104(2): 299-309, Jan 2019.

Hayeck, T J., et al.: Mixed Model Association with Family-Biased Case-Control Ascertainment. The American Journal of Human Genetics 100(1): 31-39, Jan 2017.

Vilhjálmsson, B. J., Yang, J., Finucane, H. K., Gusev, A., Lindström, S., Ripke, S., Hayeck, T.J. Price, A. L.: Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores. The American Journal of Human Genetics 97(4): 576-592, Oct 2015.

Hayeck, T. J., Zaitlen, N. A., Loh, P. R., Vilhjalmsson, B., Pollack, S., Gusev, A and Patterson, N…Price, A. L.: Mixed Model with Correction for Case-control Ascertainment Increases Association Power. The American Journal of Human Genetics, 96(5): 720-730, May 2015.

Kong, C. Y., Nattinger, K. J., Hayeck, T. J., Omer, Z. B., Wang, Y. C., Spechler, S. J., Hur, C.: The Impact of Obesity on the Rise in Esophageal Adenocarcinoma Incidence: Estimates from a Disease Simulation Model. Cancer Epidemiology Biomarkers & Prevention 20(11): 2450-2456, Nov 2011.

Hayeck, T. J., Kong, C. Y., Spechler, S. J., Gazelle, G. S., and Hur, C.: The Prevalence of Barrett's Esophagus in the US: Estimates from a Simulation Model Confirmed by SEER Data. Diseases of the Esophagus 23(6): 451-457, Aug 2010.

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Last updated: 01/23/2023
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