Elizabeth M Margolskee, MD MPH

faculty photo
Associate Professor of Clinical Pathology and Laboratory Medicine
Hematopathologist, Hospital of the University of Pennsyvania
Director of Hematology Laboratory, The Children's Hospital of Philadelphia
Associate Chair, Workforce Resiliency, The Children's Hospital of Philadelphia
Department: Pathology and Laboratory Medicine

Contact information
3401 Civic Center Boulevard
Philadelphia, PA 19104
Office: 6316808643
Lab: 2674265262
Education:
AB
Harvard University, Cambridge, MA, 2006.
MD
Mount Sinai School of Medicine, New York, NY, 2010.
MPH (Epidemiology)
Columbia University Mailman School of Public Health, 2014.
Permanent link
 
> Perelman School of Medicine   > Faculty   > Details

Description of Clinical Expertise

I am a hematopathologist and Director of the hematology laboratory at Children's Hospital of Philadelphia. I came to hematopathology originally because I wanted to care for critically ill patients alongside intelligent, curious clinicians in a collaborative fashion. I also enjoy interacting with our strong flow cytometrists, medical technologists, molecular pathologists, cytogeneticists, histotechs and pathology assistants, who make my work possible.

I am interested in quality and process improvement in the lab, and I am particularly fascinated by pediatric myeloid neoplasms.

Description of Other Expertise

On my first day as a lab director, I learned that our entire dayshift staff had been exposed to COVID-19 in the workplace and had to quarantine. Although no one became seriously ill, this experience framed my relationship with laboratory professionals, and highlighted their role as front line workers.

I work closely with Surabhi Mulchandani, Vice Chair for Laboratory Administration, and other leadership in the department, to develop sustainable, ongoing strategies to develop and strengthen the pathology workforce.

Selected Publications

Holly Hatch: District Implementation Guide: Building CTE Pathways in Laboratory Medicine. American Society for Clinical Pathology 2026.

Elizabeth Margolskee, Robert Klenk, Tracey Polsky: An electronic health record-based solution to reduce the volume of CBC differentials performed on inpatients. American Journal of Clinical Pathology 164(5): 806-812, November 2025.

Elizabeth Margolskee, Robert Klenk, Tracey Polsky: An electronic health record-based solution to reduce the volume of CBC differentials performed on inpatients. American Journal of Clinical Pathology 164(5): 806-812, November 2025.

Margolskee E, Klenk R, Polsky T: An electronic health record-based solution to reduce the volume of CBC differentials performed on inpatients. American Journal of Clinical Pathology 164(5): 806-812, November 2025.

Elizabeth Margolskee, Robert Klenk, Tracey Polsky: An electronic health record-based solution to reduce the volume of CBC differentials performed on inpatients. American Journal of Clinical Pathology 164(5): 806-812, November 2025.

Elizabeth Margolskee, Robert Klenk, Tracey Polsky: An electronic health record-based solution to reduce the volume of CBC differentials performed on inpatients. American Journal of Clinical Pathology 164(5): 806-812, November 2025.

Elizabeth Margolskee, Robert Klenk, Tracey Polsky: An electronic health record-based solution to reduce the volume of CBC differentials performed on inpatients. American Journal of Clinical Pathology 164(5): 806-812, November 2025.

Lahiri A, Shukla S, Stear B, Ahooyi TM, Beigel K, Margolskee E, Taylor D.: Benchmarking Transformer Embedding Models for Biomedical Terminology Standardization. Mach Learn Appl 21: 100683, Sept 2025.

Zheng DJ, Margolskee E, Borek RC, Devine KJ.: EBV-Negative CD20+ Plasma Cell Posttransplant Lymphoproliferative Disorder of the Airway following Liver Transplant in a 16-Month Old. Pediatr Blood Cancer 79(9): e31901, Sept 2025.

Li D, Tasian SK, Wertheim G, Rheingold SR, Bernt KM, Newman H, Wainwright L, Wilmoth DM, Thiel B, Surrey LF, Margolskee E, Pillai V, Luo M, Paessler ME, Hunger SP, Li MM, Zhong Y.: Integrated genomic analysis to reduce chromosomal analysis for the diagnosis of pediatric hematologic malignancies: addressing the shortage of cytogenetic technologists. Haematologica 110(8): 1861-1864, Aug 2025.

back to top
Last updated: 03/17/2026
The Trustees of the University of Pennsylvania