Elizabeth M Margolskee, MD MPH

faculty photo
Assistant Professor of Clinical Pathology and Laboratory Medicine
Hematopathologist, Hospital of the University of Pennsyvania
Director of Hematology, The Children's Hospital of Philadelphia
Associate Chair, Workforce Resiliency, The Children's Hospital of Philadelphia
Department: Pathology and Laboratory Medicine

Contact information
3401 Civic Center Boulevard
Philadelphia, PA 19104
Office: 6316808643
Lab: 2674265262
Harvard University, Cambridge, MA, 2006.
Mount Sinai School of Medicine, New York, NY, 2010.
MPH (Epidemiology)
Columbia University Mailman School of Public Health, 2014.
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Description of Clinical Expertise

I am a hematopathologist and Director of the hematology laboratory at Children's Hospital of Philadelphia. I came to hematopathology originally because I wanted to care for critically ill patients alongside intelligent, curious clinicians in a collaborative fashion. I also enjoy interacting with our strong flow cytometrists, medical technologists, molecular pathologists, cytogeneticists, histotechs and pathology assistants, who make my work possible.

I am interested in quality and process improvement in the lab, and I am particularly fascinated by pediatric myeloid neoplasms.

Description of Other Expertise

On my first day as a lab director, I learned that our entire dayshift staff had been exposed to COVID-19 in the workplace and had to quarantine. Although no one became seriously ill, this experience framed my relationship with laboratory professionals, and highlighted their role as front line workers.

I work closely with Surabhi Mulchandani, Vice Chair for Laboratory Administration, and other leadership in the department, to develop sustainable, ongoing strategies to develop and strengthen the pathology workforce.

Selected Publications

Fenu EM, Margolskee E, Pillai V: Transdifferentiation of B-lymphoblastic Leukemia to Histiocytic Sarcoma After Immunotherapy. American journal of hematology 98(8): E216-E218, August 2023.

Margolskee E.: 2023 Digital Slide Program in Hematopathology: Case 6: Juvenile Myelomonocytic Leukemia (JMML). College of American Pathologists (CAP) Hematopathology Committee. CAP, 2023.

Thompson R, Zoltowski M, Lim D, Diorio C, Margolskee M, Paessler M, Bochenek V, Behrens EM, Teachey DT, Massiri H, Lambert MP, Gollomp K: Quantification of Neutrophil Extracellular Traps (NETs) in Pediatric Patients with COVID-19 and Multisystem Inflammatory Syndrome (MIS-C) through Plasma and Peripheral Smear Analysis. American Society of Hematopathology 64th Annual Meeting, New Orleans November 2022 Notes: Poster Presentation.

Drumheller B, Gebre K, Lockhart B, Margolskee E, Obstfeld A, Paessler M, Pillai V: Haematology Laboratory Parameters to Assess Efficacy of CD19-, CD22-, CD33-, and CD123-directed Chimeric Antigen Receptor T-cell Therapy in Haematological Malignancies. International Journal of Laboratory Hematology 44(4): 750-758, August 2022.

Whitener V, Barry D, Helfrich M, Forman J, Zoltowski M, Lim D, Williams E, Shah V, Margolskee B, Bidegary A: Improving STAT CBCDI Turnaround Times. CHOP Quality Improvement and Patient Safety Day June 2022 Notes: Poster Presentation.

Xu Z, Wat M, Pillai V, Margolskee E, Rubin AI, Khurana MC : An Erythematous Indurated Plaque on the Neck of a 12-year-old Girl. Pediatr Dermatol 39(3): 449-451, May 2022.

Xu Z, Margolskee E, Villasenor-Park J, Rubin AI, Khurana MC: A Healthy 16-year-old Boy Presenting with Multifocal Asymptomatic Subcutaneous Nodules. Pediatr Dermatol 39(1), January 2022.

El-Sharkawy F, Margolskee E: Pediatric Myeloproliferative Neoplasms. Clinics in Laboratory Medicine 41(3): 529-540, September 2021.

Papachristodoulou A, Rodriguez-Calero A, Panja S, Margolskee E, Virk RK, Milner TA, Martina LP, Kim JY, Di Bernardo M, Williams AB, Maliza EA, Caputo JM, Haas C, Wang V, De Castro GJ, Wenske S, Hibshoosh H, McKiernan JM, Shen MM, Rubin MA, Mitrofanova A, Dutta A, Abate-Shen C: NKX3.1 Localization to Mitochondria Suppresses Prostate Cancer Initiation. Cancer Discovery 11(9): 2316-2333, September 2021.

Margolskee E, Wertheim GBW, Harvey RC: Pathology and Molecular Diagnosis of Leukemias and Lymphomas. Pizzo and Poplack's Pediatric Oncology 8th Edition Page: 117-128, 2021.

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Last updated: 12/07/2023
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