Matthew Knarr, PhD
Research Associate of Obstetrics and Gynecology
Research Associate, University of Pennsylvania
Department: Obstetrics and Gynecology
Contact information
421 Curie Blvd
Rm 1224 BRB2/3
Philadelphia, PA 19104
Rm 1224 BRB2/3
Philadelphia, PA 19104
Office: 7179199530
Publications
Education:
B.S. (Cellular & Organismal Biology)
Lock Haven University, 2013.
A.A.S. (Nanotechnology)
Lock Haven University, 2013.
Ph.D. (Pharmacology)
Case Western Reserve University, 2019.
Permanent linkB.S. (Cellular & Organismal Biology)
Lock Haven University, 2013.
A.A.S. (Nanotechnology)
Lock Haven University, 2013.
Ph.D. (Pharmacology)
Case Western Reserve University, 2019.
Selected Publications
Knarr MJ, Moon J, Rawat P, DiFeo A, Hoon DSB, Drapkin R.: Repurposing colforsin daropate to treat MYC-driven high-grade serous ovarian carcinomas. Sci Signal 17: eado8303, Nov 2024.Reavis HD, Gysler SM, McKenney GB, Knarr M, Lusk HJ, Rawat P, Rendulich HS, Mitchell MA, Berger DS, Moon JS, Ryu S, Mainigi M, Iwanicki MP, Hoon DS, Sanchez LM, Drapkin R.: Norepinephrine induces anoikis resistance in high-grade serous ovarian cancer precursor cells. JCI Insight 9: e170961, Mar 2024.
Bustos MA, Yokoe T, Shoji Y, Kobayashi Y, Mizuno S, Murakami T, Zhang X, Sekhar SC, Kim S, Ryu S, Knarr M, Vasilev SA, DiFeo A, Drapkin R, Hoon DSB.: MiR-181a targets STING to drive PARP inhibitor resistance in BRCA- mutated triple-negative breast cancer and ovarian cancer. Cell Biosci 13: 200, Nov 2023.
Belur Nagaraj A, Knarr M, Sekhar S, Connor RS, Joseph P, Kovalenko O, Fleming A, Surti A, Nurmemmedov E, Beltrame L, Marchini S, Kahn M, DiFeo A.: The miR-181a-SFRP4 Axis Regulates Wnt Activation to Drive Stemness and Platinum Resistance in Ovarian Cancer. Cancer Res 81: 2044-2055, Apr 2021.
Knarr M, Avelar RA, Sekhar SC, Kwiatkowski LJ, Dziubinski ML, McAnulty J, Skala S, Avril S, Drapkin R, DiFeo A.: miR-181a initiates and perpetuates oncogenic transformation through the regulation of innate immune signaling. Nat Commun 11: 3231, Jun 2020.
Knarr M, Nagaraj AB, Kwiatkowski LJ, DiFeo A.: miR-181a modulates circadian rhythm in immortalized bone marrow and adipose derived stromal cells and promotes differentiation through the regulation of PER3. Sci Rep 9: 307, Jan 2019.