Michael George Fradley, MD

faculty photo
Associate Professor of Clinical Medicine (Cardiovascular Medicine)
Medical Director, Thaleheimer Center for Cardio-Oncology, Hospital of the University of Pennsylvania
Section Chief, Consultative Cardiology, Hospital of the University of Pennsylvania
Associate Chief, Outpatient Services , Hospital of the University of Pennsylvania
Department: Medicine

Contact information
3400 Civic Center Blvd, 2-349 PCAM
Philadelphia, PA 19104
Office: 215-220-9440
Education:
BS (Molecular Biophysics and Biochemistry)
Yale University, New Haven, CT, 2001.
MD (Medicine)
Johns Hopkins School of Medicine, Baltimore, MD, 2005.
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Selected Publications

Michal M Farkowski, Sebastian Szmit, Giuseppe Boriani, Sergio Castrejon, Michael Fradley, Avirup Guha, Josè L Merino, Giacomo Mugnai, Geraldine A Lee, Alexander R Lyon, Diego Penela, Laura Perrotta, Teresa Lopez-Fernandez, Julian K R Chun: Contemporary management of atrial fibrillation in patients with cancer-the 2025 European Heart Rhythm Association survey. Europace Feb 2026.

Samia Shabnaz, Eric Farber-Eger, Marwa Tantawy, Neyousha Shahisavandi, Timothy J Garrett, Samuel M Rubinstein, Michael G Fradley, Mohammed E Alomar, Danny DeAvila, Kenneth H Shain, R Frank Cornell, Daniel Lenihan, Qing Lu, Quinn S Wells, Rachid C Baz, Yan Gong: Causal Effects of Hydrophilic Bile Acids on Carfilzomib-Related Cardiovascular Events in Multiple Myeloma: A Mendelian Randomization Study. Clinical Pharmacology & Therapeutics 2026.

Daniel S Lefler, Elise F Nassif Haddad, Anju Nohria, Mark Agulnik, Jacquelyn Crane, Michael G Fradley: Sarcoma: Cardiovascular and Oncologic Considerations: JACC: CardioOncology State-of-the-Art Review. JACC CardioOncology 7(7): 800-815, Dec 2025.

Lakshya Seth, Nickolas Stabellini, Shawn Doss, Vraj Patel, Viraj Shah, Gregory Lip, Susan Dent, Michael G Fradley, Lars Køber, Avirup Guha: Atrial fibrillation and ischemic stroke in cancer: the latest scientific evidence, current management, and future directions. Journal of Thrombosis and Thrombolysis 58(8): 1081-1094, Dec 2025.

Lakshya Seth, Nickolas Stabellini, Aditya Bhave, Gaurav Gopu, Sandeep Yerraguntla, Ahmed Shetewi, John Lester, Vraj Patel, Stephanie Jiang, Madison James, Stanley Joseph, Sai Kollapaneni, Viraj Shah, Susan Dent, Michael G Fradley, Lars Køber, Anne Blaes, Avirup Guha: The B-S2CALED Score's Utility in Predicting Stroke Risk in Breast Cancer Patients with Atrial Fibrillation. Cancers (Basel) 17(22): 3600, Nov 2025.

Yanfei Wang, Shu Niu, Bently P Doonan, Avirup Guha, Michael Fradley, Yonghui Wu, Steven M Smith, Yan Gong, Qianqian Song: Real-world analysis of cardiovascular adverse events and risk factors after immune checkpoint inhibitor therapy. CardioOncology 11(1): 107, Nov 2025.

Ashraf Alzahrani, Kaushik Gokul, Aswathi Paleri, Edward M Powers, Steven Bailin, Eric H Yang, Michael Fradley, Peter Farjo, Paari Dominic : New-onset atrial fibrillation as a predictor of cancer: Insights from a real-world dataset. Heart Rhythm(24), 03021-8, Oct 2025 Notes: https://doi.org/10.1016/j.hrthm.2025.10.040.

Poojita Shivamurthy, Marisa Cevasco, Gregory E Supple, Balaram Krishna Hanumanthu, Timothy M Markman, Gustavo Guandalini, Matthew C Hyman, Andres Enriquez, Ramanan Kumareswaran, Michael G Fradley, Rajat Deo, Vincent Y See, Michael Riley, Fermin Garcia, Saman Nazarian, David Lin, David S Frankel, Sanjay Dixit, Andrew E Epstein, David J Callans, Francis E Marchlinski, Robert D Schaller : Epicardial placement of implantable cardioverter-defibrillators in adults: Technical considerations, system performance, and clinical outcomes. Heart Rhythm 22(10): e908-918, Oct 2025.

Daniel Lenihan, Michelle Bloom, Robert Copeland-Halperin, Matthew R Fleming, Michael Fradley, Rupal O'Quinn, Seema A Bhat : Considerations for the practical management of cardiovascular risk with Bruton's tyrosine kinase inhibitors for patients with chronic lymphocytic leukemia. Oncologist 30(9): 237, Sep 2025.

Priyanshu Nain, Omar M Makram, Viraj Shah, Harikrishnan Hyma Kunhiraman, Nickolas Stabellini, Biplab Datta, Stephanie Jiang, Vraj Patel, Lakshya Seth, Aditya Bhave, Sarah A Malik, Yan Gong, Michael G Fradley, Darryl P Leong, Ryan A Harris, Yi-Hsin Hung, Austin Yen-Hung Lin, Neal L Weintraub, Avirup Guha: Impact of Diabetes and Metformin on Cardiovascular Outcomes in Prostate Cancer Patients Aged 66 and Older: The Role of Social Determinants of Health and Racial Disparities. Cancers (Basel) . 17(17): 2854, Aug 2025.

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Last updated: 03/08/2026
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