Jan-Karl Burkhardt, MD
The James and Agnes Kim Associate Professor of Neurosurgery
Director, Neurovascular Tissue Bank and Translational Lab, Burkardt Lab, Department of Neurosurgery, Perelman School of Medicine at the University of Pennsylvania
Director, Center of Excellence - Cavernous Malformation, Hospital of the University of Pennsylvania, Penn Medicine
Educational Site Director, Department of Neurosurgery, The Hospital of the University of Pennsylvania
Director, Cerebral Revascularization Program, Hospital of the University of Pennsylvania, Department of Neurosurgery
Director, Neurointerventional Fellowship Program, Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania
Neurosurgical Director, Comprehensive Stroke Center, Department of Neurosurgery, University of Pennsylvania
Division Head, Cerebrovascular Surgery , Hospital Of the University of Pennsylvania, Penn Medicine
Department: Neurosurgery
Contact information
Department of Neurosurgery
3400 Civic Center Blvd
15th Floor, South Tower
Philadelphia, PA 19104
3400 Civic Center Blvd
15th Floor, South Tower
Philadelphia, PA 19104
Publications
Education:
MD
University of Leipzig, Germany, 2007.
MD Thesis
University of Leipzig, Germany, 2009.
PhD (Venia Legendi, Habilitation)
University of Zurich, Switzerland, 2016.
Permanent linkMD
University of Leipzig, Germany, 2007.
MD Thesis
University of Leipzig, Germany, 2009.
PhD (Venia Legendi, Habilitation)
University of Zurich, Switzerland, 2016.
Description of Clinical Expertise
Primary Area of Expertise / Neurosurgical Interests:Aneurysms, Arteriovenous Malformations (AVMs), Arteriovenous Fistulas (AVFs) and Cerebral Cavernous Malformations. Cerebral Revascularization and Extracranial-Intracranial (EC-IC) and IC-IC Bypass Procedures. Moyamoya Disease, Subarachnoid Hemorrhage, Intracranial Hemorrhage, Acute Ischemic Stroke and Chronic Vessel Stenosis or Occlusion.
Interested in both open microsurgical vascular and endovascular neurosurgery/neuroradiology.
Description of Research Expertise
Revascularization, Moyamoya diseaseSelected Publications
Patel SA, Vivanco-Suarez J, Palepu C, Chisvo NS, Patel S, Gajjar AA, Woodiwiss T, Burkhardt JK, Srinivasan VM.: Intrasaccular Flow Disruption: Examining Global Access and Research Trends. World Neurosurg Jul 2024.Salah WK, Findlay MC, Baker CM, Scoville JP, Bounajem MT, Ogilvy CS, Moore JM, Riina HA, Levy EI, Siddiqui AH, Spiotta AM, Cawley CM, Khalessi AA, Tanweer O, Hanel R, Gross BA, Kuybu O, Howard BM, Hoang AN, Baig AA, Khorasanizadeh M, Mendez Ruiz AA, Cortez G, Davies JM, Lang MJ, Thomas AJ, Tonetti DA, Khalife J, Sioutas GS, Carroll K, Abecassis ZA, Jankowitz BT, Ruiz Rodriguez J, Levitt MR, Kan PT, Burkhardt JK, Srinivasan V, Salem MM, Grandhi R.: The Influence of Coagulopathy on Radiographic and Clinical Outcomes in Patients Undergoing Middle Meningeal Artery Embolization as Standalone Treatment for Non-acute Subdural Hematomas. J Neurotrauma Jul 2024.
Vranic JE, Dmytriw AA, Berglar IK, Alotaibi NM, Cancelliere NM, Stapleton CJ, Rabinov JD, Harker P, Gupta R, Bernstock JD, Koch MJ, Raymond SB, Mascitelli JR, Patterson TT, Seinfeld J, White A, Case D, Roark C, Gandhi CD, Al-Mufti F, Cooper J, Matouk C, Sujijantarat N, Devia DA, Ocampo-Navia MI, Villamizar-Torres DE, Puentes JC, Salem MM, Baig A, El Namaani K, Kühn AL, Pukenas B, Jankowitz BT, Burkhardt JK, Siddiqui A, Jabbour P, Singh J, Puri AS, Regenhardt RW, Mendes Pereira V, Patel AB.: The Impact of Preprocedural Platelet Function Testing on Periprocedural Complication Rates Associated With Pipeline Flow Diversion: An International Multicenter Study. Neurosurgery 95: 179-185, Jul 2024.
Hendrix P, Gross BA, Allahdadian S, Sioutas GS, Koul P, Tarbay AC, Lang MJ, Srinivasan VM, Al-Bayati AR, Li J, Noto A, Nogueira RG, Burkhardt JK, Zand R, Schirmer CM.: Tenecteplase versus alteplase before stroke thrombectomy: outcomes after system-wide transitions in Pennsylvania. J Neurol Jul 2024.
El Naamani K, Roy JM, Momin AA, Teichner EM, Sioutas GS, Salem MM, Gaskins W, Saadat N, Nguyen AM, Tjoumakaris SI, Gooch MR, Rosenwasser RH, Srinivasan V, Jankowitz BT, Burkhardt JK, Jabbour PM.: The Era of Radial-Specific Catheters: A Multicenter Comparison of the Armadillo and RIST Catheters in Transradial Procedures. Oper Neurosurg (Hagerstown) Jul 2024.
Muhammad N, Ramayya A, Burkhardt JK, Srinivasan VM.: Urgent carotid endarterectomy with distal mechanical thrombectomy. J Neurointerv Surg Jun 2024.
Ahmad H, Albayar A, Muhammad N, Romeo D, Salem M, Yang AI, Burkhardt JK.: Ruptured Anterior Inferior Cerebellar Artery Aneurysm From a Persistent Trigeminal Artery: A Case Report. Cureus 16: e60648, May 2024.
McCloskey K, Gajjar AA, Salem MM, Susca L, Sioutas GS, Srinivasan VM, Jankowitz BT, Burkhardt JK.: Intraoperative Ionizing Radiation Exposure Awareness and Associated Morbidity in Neurosurgery: A Nationwide Survey. World Neurosurg May 2024.
Drexler R, Sauvigny J, Pantel TF, Ricklefs FL, Catapano JS, Wanebo JE, Lawton MT, Sanchin A, Hecht N, Vajkoczy P, Raygor KP, Tonetti DA, Abla A, Naamani KE, Tjoumakaris SI, Jabbour P, Jankowitz BT, Salem MM, Burkhardt JK, Wagner A, Wostrack M, Gempt J, Meyer B, Gaub M, Mascitelli JR, Dodier P, Bavinzski G, Roessler K, Stroh N, Gmeiner M, Gruber A, Figueiredo EG, Samaia da Silva Coelho AC, Bervitskiy AV, Anisimov ED, Rzaev JA, Krenzlin H, Keric N, Ringel F, Park D, Kim MC, Marcati E, Cenzato M, Westphal M, Sauvigny T, Dührsen L.: Sex-dependent characteristics and outcomes after clipping of unruptured intracranial aneurysms: a multicenter propensity score-matched study. J Neurosurg May 2024.
Chintapalli R, Nguyen S, Taussky P, Grandhi R, Dammann P, Raygor K, Tonetti DA, Andersson T, White P, Ogilvy CS, Chapot R, Fox WC, Tawk RG, Lanzino G, Hanel R, Jadhav A, Hassan AE, Linfante I, Almefty R, Mascitelli J, Fargen K, Levitt MR, Burkhardt JK, Jankowitz BT, Jabbour P, Starke RM, Gross BA, Kan P, Killer-Oberpfalzer M, Rautio R, Dmytriw AA, Coulthard A, Dabus G, Raper D, Deuschl C, Kilburg C, Budohoski KP, Abla AA.: Management of failed flow diversion for intracranial aneurysm beyond the first 6 months of follow-up: an international Delphi consensus. J Neurosurg May 2024.