Joel S. Karp, Ph.D.

faculty photo
Professor of Radiologic Physics in Radiology
Administrator, Hospital of the University of Pennsylvania Health Care Provider
Section Chief, Hospital of the University of Pennsylvania Department of Radiology - Physics & Instrumentation Group
Sub-Core Director, Hospital of the University of Pennsylvania PET/SPECT/CT, Small Animal Imaging Facility
Director, Hospital of the University of Pennsylvania Physics, Positron Emission Tomography Facility
Department: Radiology
Graduate Group Affiliations

Contact information
University of Pennsylvania
Department of Radiology
Physics & Instrumentation Group
3620 Hamilton Walk
1st Floor John Morgan Building - Room #154
Philadelphia, PA 19104-6112
Office: 215-573-4998
Fax: 215-573-3880
Education:
B.S. (Physics)
State University of New York at Stony Brook, 1975.
Ph.D. (Physics)
Massachusetts Institute of Technology, 1980.
Permanent link
 
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Selected Publications

Kwon D, Li EJ, Dulal C, Daube-Witherspoon MED, Viswanath V, Hou-Liu J, Mankoff DA, Karp JS, Pantel AR: "Dual-tracer Imaging on a Long-Axial Field-Of-View PET: A Proof-Of-Principle Study with [18F]Fluoroglutamine and [18F]Fluorodeoxyglucose" Journal of Nuclear Medicine July 2025.

Huang B, Dai B, Lapi SE, Liles G, Karp JS, Qi J: "High-resolution Positronium Lifetime Tomography on the PennPET Explorer" Journal of Nuclear Medicine July 2025.

Daube-Witherspoon ME, Moore SC, Karp JS: "Randoms Estimation for Long Axial Field-of-View PET" IEEE TRPMS July 2025.

Dai B, Krishnamoorthy, S, Morales E, Surti S, Karp JS: "Depth-of-interaction Encoding Techniques for Pixelated PET Detectors Enabled by Machine Learning Methods and Fast Waveform Digitization" Phys Med Biol April 2025.

Muller FM, Li EJ, Daube-Witherspoon ME, Pantel AR, Wiers CE, Dubroff JG, Vanhove C, Vandenberghe S, Karp JS: "Impact of Deep Learning Denoising on Kinetic Modelling for Low-Dose Dynamic PET: Application for Single- and Dual-Tracer Imaging Protocols" European Journal of Nuclear Medicine and Molecular Imaging March 2025.

Gao M, Daube-Witherspoon ME, Karp JS, Surti S: "Total-Body PET system Designs with Axial and Transverse Gaps: A Study of Lesion Quantification and Detectability" Journal of Nuclear Medicine January 2025.

Raj J, Millardet M, Krishnamoorthy S, Karp JS, Surti S, Matej S: "Recovery of the spatially-variant deformations in dual-panel PET reconstructions using deep-learning" Phys Med Biol 69, February 2024.

Hamill JJ, Cabello J, Karp JS, Surti S: "Energy-Based Scatter Estimation in Clinical PET/CT" Medical Physics 51, January 2024.

Muller FM, Vervenne B, Maebe J, Karp JS, Vanhove C, Vandenberghe S: "Image Denoising low dose PET Mouse Imaging with Deep Learning; Validation study for Preclinical Imaging Applicability" Mol Imaging and Biol 26, October 2023.

Vandenberghe S, Muller FM, Withofs N, Dadgar M, Maebe J, Vervenne B, Abi Akl M, Xue S, Shi K, Sportelli G, Belcari N, Hustinx R, Vanhove C, Karp JS: "Walk-through flat panel total-body PET: a patient-centered design for high throughput imaging at lower cost using DOI-capable high-resolution monolithic detectors" Eur J Nucl Med and Mol Imag July 2023.

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Last updated: 09/02/2025
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