George T Kannarkat, MD, PhD
Assistant Professor of Neurology at the Hospital of the University of Pennsylvania
Department: Neurology
Contact information
3900 Woodland Avenue
Philadelphia, PA 19104-4551
Philadelphia, PA 19104-4551
Publications
Education:
BA (Biology, International Studies)
Baylor University, 2009.
PhD
Emory University School of Medicine, 2016.
MD
Emory University School of Medicine, 2017.
Permanent linkBA (Biology, International Studies)
Baylor University, 2009.
PhD
Emory University School of Medicine, 2016.
MD
Emory University School of Medicine, 2017.
Description of Clinical Expertise
Movement disorders clinician who focuses on Parkinson's disease, REM-sleep behavior disorder, and those at-risk for neurodegenerative disease.Description of Research Expertise
Physician-scientist who is interested in mechanisms outside the brain (inflammation, protein misfolding, and environmental toxicants) that contribute to neurodegeneration.Selected Publications
George Kannarkat, Dimple Chouhan, D. Kacy Cullen, John Duda: Tissue-Engineered Nigrostriatal Pathways (TE-NSPs)Serve as a Novel Tool to Study the Cell-to-Cell Spread of Pathologic Alpha-Synuclein. American Neurological Association Annual Meeting 2025 2025.George Kannarkat: The Source and Pathogenic Potential of Blood-derived Alpha-Synuclein. American Academy of Neurology Annual Meeting 2025 2025.
George Kannarkat, Travis Unger, Robert Skrinak, Caroline Lewis, Kelvin Luk, Thomas Tropea, Daniel Weintraub, Alice Chen-Plotkin: Blood-Derived Alpha-Synuclein Strains in Lewy Body Diseases are Associated with Extracellular Vesicles and Induce Cellular Inclusions. American Neurological Association Annual Meeting 2025 2025.
Nathan Zhang, Andres Fernandez del Castillo, George Kannarkat: Establishing the Parkinson's Disease At-Risk Clinic (PD-ARC). American Neurological Association Annual Meeting 2025 2025.
Kannarkat GT, Zack R, Skrinak RT, Morley JF, Davila-Rivera R, Arezoumandan S, Dorfman K, Luk K, Wolk DA, Weintraub D, Tropea TF, Lee EB, Xie SX, Chandrasekaran G, Lee VM, Irwin D, Akhtar RS, Chen-Plotkin AS.: Blood α-Synuclein Separates Parkinson's Disease from Dementia with Lewy Bodies. Ann Neurol 2025.
Gilboa T, Ter-Ovanesyan D, Wang SC, Whiteman S, Kannarkat GT, Church GM, Chen-Plotkin AS, Walt DR.: Measurement of α-synuclein as protein cargo in plasma extracellular vesicles. Proc Natl Acad Sci U S A 121: e2408949121, Nov 2024.
Kannarkat GT, Zack R, Skrinak RT, Morley JF, Davila-Rivera R, Arezoumandan S, Dorfmann K, Luk K, Wolk DA, Weintraub D, Tropea TF, Lee EB, Xie SX, Chandrasekaran G, Lee VM, Irwin D, Akhtar RS, Chen-Plotkin AS.: α-Synuclein Conformations in Plasma Distinguish Parkinson's Disease from Dementia with Lewy Bodies. Res Sq Sep 2024.
Kannarkat JT, Kannarkat GT, Jones LK Jr.: Neurologic Alternative Payment Models-Bridging the Gap. JAMA Neurol Jan 2024.
Tropea TF, Kannarkat GT, Shaw LM.: Early and Accurate Diagnosis of Parkinson’s Disease May Be Rooted in Seed Amplification Assays. Clinical Chemistry 69(11), Nov 2023 Notes: DOI: 10.1093/clinchem/hvad111.
Tropea TF, Kannarkat GT, Shaw LM.: Early and Accurate Diagnosis of Parkinson Disease May Be Rooted in Seed Amplification Assays. Clin Chem 69: 1209-1211, Nov 2023.