Mauro Hanaoka, M.D.

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Assistant Professor of Clinical Radiology
Active Radiologist, Department of Radiology, Chester County Hospital
Active Radiologist, Department of Radiology, Penn Presbyterian Medical Center
Active Radiologist, Department of Radiology, Pennsylvania Hospital
Attending, Department of Radiology, Hospital of the University of Pennsylvania
Department: Radiology

Contact information
Hospital of the University of Pennsylvania
Department of Radiology
3400 Spruce Street
One Silverstein Building
Philadelphia, PA 19104-4283
Education:
M.D. (Medicine)
University of Sao Paulo, 2009.
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Description of Clinical Expertise

I specialize in advanced neuroimaging of the brain, spine, and head and neck, with expertise in techniques that support precise diagnosis and clinical decision-making. In addition, I perform a wide range of image-guided procedures, including biopsies, myelography, epidural injections, and targeted blood patches, steroid injections. I am equally passionate about education, providing hands-on teaching and mentorship to residents and fellows as they develop expertise in neuroradiology.

Description of Research Expertise

My research focuses on advanced neuroimaging techniques, including tractography and MR spectroscopy, to better characterize brain connectivity, metabolism, and disease processes. Through these methods, I aim to improve diagnostic precision, guide treatment planning, and expand our understanding of complex neurologic disorders.

Selected Publications

Seyyed Ali Hosseini, Ghasem Hajianfar, Pardis Ghaffarian, Milad Seyfi, Elahe Hosseini, Atlas Haddadi Aval, Stijn Servaes, Mauro Hanaoka, Pedro Rosa-Neto, Sanjeev Chawla, Habib Zaidi, Mohammad Reza Ay: PET radiomics-based lymphovascular invasion prediction in lung cancer using multiple segmentation and multi-machine learning algorithms. Phys Eng Sci Med 47(4): 1613-1625, December 2024.

Laiz Laura de Godoy, Kheng Choon Lim, Archith Rajan, Gaurav Verma, Mauro Hanaoka , Donald M O'Rourke, John Y K Lee, Arati Desai , Sanjeev Chawla, Suyash Mohan: Non-Invasive Assessment of Isocitrate Dehydrogenase-Mutant Gliomas Using Optimized Proton Magnetic Resonance Spectroscopy on a Routine Clinical 3-Tesla MRI. Cancers 15(18): 4453, September 2023 Notes: https://pubmed.ncbi.nlm.nih.gov/37760422/

Wang X, Shikoh F, Clark A, Hanaoka M. : Avoidable and Unavoidable Repeat Breast Core Needle Biopsies. Arch Breast Cancer [Internet] 9(1): 32-39, Jan 2022 Notes: Available from: https://www.archbreastcancer.com/index.php/abc/article/view/45.

Kapoor H, Hanaoka M, Dawkins A, Khurana A: Review of MRI imaging for placenta accreta spectrum: Pathophysiologic insights, imaging signs, and recent developments. Placenta 104: 31-39, Jan 2021.

Aal AKA, Moawad S, Lune PV, El Khudari H, Hanaoka MM, Abouldahab N, Gunn AJ, White J, Shoreibah M, Li Y, Saddekni S, Mahmoud K: Survival Outcomes of Very Small Drug-Eluting Beads Used in Chemoembolization of Unresectable Hepatocellular Carcinoma. Journal Vasc. Interv. Radiology 30(9): 1325-1334, Sep 2019.

Aal A, Moawad S, Jackson B, Hanaoka M, Baalmann C, Ertel N, Pettibon K, Harris A, Patel A, Lambertsen Z, Newman G, Saddekni S: Tumor response and survival outcomes of very small drug-eluting beads used in transarterial chemoembolization for unresectable hepatocellular carcinoma. Journal of Vascular and Interventional Radiology. 28(2): S124–S125, Feb 2017 Notes: https://www.jvir.org/article/S1051-0443(16)31797-3/fulltext.

Aal A, Shoreibah M, Kim S, Jackson B, Moawad S, Hanaoka M, Massoud M, Saddekni S: Psoas muscle density predicts survival of cirrhotic patients undergoing transjugular intrahepatic portosystemic shunt. Journal of Vascular and Interventional Radiology 28(2): S168, Feb 2017.

Aal A, Moawad S, Hanaoka M, Jackson B, Abouarab A, Tatum T, Jacob R, Saddekni S. : Adjuvant stereotactic body radiotherapy following transarterial chemoembolization using small diameter drug-eluting beads in patients with unresectable hepatocellular carci. Adjuvant stereotactic body radiotherapy following transarterial chemoembolization using small diameter drug eluting beads in patients with unresectable hepatocellular carcinoma tumors of equal or greater than 3 cm. Journal of Vascular and Interventional Radiology 28(2): S80, Feb 2017.

Raghavan ML, Hanaoka MM, Kratzberg JA, Higuchi ML, da Silva ES: Biomechanical failure properties and microstructural content of ruptured and unruptured abdominal aortic aneurysms. Journal of Biomechanics 44(13): 2501-2507, Jul 2011.

Hensley P, Goodwin, J, Dugan A, Hanaoka M, Bylund J, Harris A: Analyzing patient-specific factors contributing to extend PACU length of stay and subsequent cost: a quality improvement initiative. . 2009, May; . Journal of Urology 201((Supplement 4)): e933, May 2009.

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Last updated: 09/19/2025
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