Katherine Scangos, M.D., Ph.D.
Adjunct Associate Professor of Neurosurgery
Associate Professor CE (Pending Review), Department of Psychiatry, Department of Neurosurgery, University of Pennsylvania
Director, Brain Circuit Therapeutics Clinic, University of Pennsylvania
Member of Center for Brain Imaging and Stimulation, University of Pennsylvania
Member of Center for Neuromodulation of Depression and Stress, University of Pennsylvania
Member of Penn Brain Science, Translation, Innovation, and Modulation Center, University of Pennsylvania
Department: Neurosurgery
Contact information
801 Spruce Street
Philadelphia, PA 19107
Philadelphia, PA 19107
Links
A ‘Pacemaker for the Brain’: No Treatment Helped Her Depression — Until This, New York Times, by Pam Bullock, Oct 4 2021
Researches Show Efficacy Of Personalized Brain Stimulation In Psychiatric Treatments, NPR, by Jon Hamilton, Jan 18, 2021
A Better Way to Zap Our Brains, New York Times Magazine, by Kim Tingley, Feb 24, 2021
Brain Implant May Lift Most Severe Depression, BBC, by Michelle Roberts, Oct 4, 2021
A ‘Pacemaker for the Brain’: No Treatment Helped Her Depression — Until This, New York Times, by Pam Bullock, Oct 4 2021
Researches Show Efficacy Of Personalized Brain Stimulation In Psychiatric Treatments, NPR, by Jon Hamilton, Jan 18, 2021
A Better Way to Zap Our Brains, New York Times Magazine, by Kim Tingley, Feb 24, 2021
Brain Implant May Lift Most Severe Depression, BBC, by Michelle Roberts, Oct 4, 2021
Education:
B.A. (Biology)
Amherst College, 2002.
MD, Ph.D. (Neuroscience)
John Hopkins School of Medicine, 2012.
Permanent linkB.A. (Biology)
Amherst College, 2002.
MD, Ph.D. (Neuroscience)
John Hopkins School of Medicine, 2012.
Selected Publications
Siddiqi SH, Chen L, Trapp NT, Bukhari-Parlakturk N, Taylor JJ, Boes AD, Brown JC, Barbour T, Camprodon JA, Fox MD, Kopell BH, MacMillan C, Fasano A, Fisher RS, Nahas Z, Revuelta GJ, Riva-Posse P, Rolston JD, Scangos K, Shafi MM, Smith AH, Wong J, Halpern CH, Mayberg HS, Williams NR.: Towards accredited clinical training in brain stimulation: Proceedings from the brain stimulation subspecialty summits. Brain Stimulation 18(2): 298-305, Feb 2025.Liming Qiu, Young-Hoon Nho, Robert Seilheimer, Min Jae Kim, Altona Tufanoglu, Nolan R. Williams, Anna Wexler, David W. Oslin, Bruno Millet, Katherine W. Scangos, Bijan Pesaran, A. Eden Evins, R. Mark Richardson, Anna-Rose Childress, Casey H. Halpern: Localizing electrophysiologic cue-reactivity within the nucleus accumbens guides deep brain stimulation for opioid use disorder. BioRXiv Feb 2025.
Starkweather CK, Sugrue LP, Cajigas I, Speidel B, Krystal AD, Scangos K, Chang EF: Stereoelectroencephalography Electrode Implantation for Inpatient Workup of Treatment-Resistant Depression. Neurosurgery 95(4): 941-948, Oct 2024.
Robert Seilheimer, Liming Qiu, Younghoon Nho, Gustavo Campos, Wonkyung Choi, Kristie Bauman, Taneeta Ganguly, Mario Cristancho, Michael Jensen, Kai Miller, Desmond Oathes, Lily Brown, Katherine Scangos, Nolan Williams, Dan Barbosa, Casey Halpern: Stereo-Electroencephalography-Guided Multi-Lead Deep Brain Stimulation for Treatment-Resistant Obsessive-Compulsive Disorder. NYC Neuromodulation Conference July-Aug 2024 Notes: https://neuromodec.org/nyc-neuromodulation-2024/poster-list.html.
Scangos, K.W, Sugrue, L.P.: From sweet spots to causal circuits: navigating deep brain stimulation targeting through anatomic, connectomic, and personalized approaches. Biol. Psych 96(2): 82-84, July 2024.
Johnson, K.A., Okun, M.S., Scangos, K.W., Mayberg H.S., de Hemptinne C.: Deep brain stimulation for refractory major depressive disorder: a comprehensive review. Mol Psychiatry 29(4): 1075-87, Jan 2024.
Gustavo Campos,Liming Qiu, Robert Seilheimer, Harvey Huang, Min Jae Kim, Zhengjia Wang, Younghoon Nho, Katherine W. Scangos, Dora Hermes, Kai J. Miller, Daniel A.N. Barbosa, Casey H. Halpern: Combining tractography and electrophysiological connectivity for hypothesis-driven network probing in stereo-electroencephalography (sEEG)-guided deep brain stimulation (DBS) for treatment-refractory obsessive-compulsive disorder (trOCD). American Society for Stereotactic and Functional Neurosurgery Meeting 2024.
Younghoon Nho,Liming Qiu, Gustavo Campos, Rob Seilheimer, Camarin Rolle, Lily Brown, Desmond Oathes, Bijan Pesaran, Katherine Scangos, Daniel Barbosa, Casey H. Halpern : Circuit-based relevant electrophysiology modulation of personalized evocation was associated with amelioration in OCD-related distress. American Society for Stereotactic and Functional Neurosurgery Biennial Meeting 2024.
Robert Seilheimer, Liming Qiu, Younghoon Nho, Gustavo Campos, Neda Kaboodvand, Kristie Bauman, Taneeta M. Ganguly, Mario Cristancho, Michael Jensen, Kai J. Miller, Lily A. Brown, Desmond J. Oathes, Katherine W. Scangos, A. Moses Lee, Nolan Williams, Daniel A.N. Barbosa, Casey H. Halpern: Stereo-electroencephalography-guided multi-lead deep brain stimulation for treatment-resistant obsessive-compulsive disorder. Brain Conference 2024.
Liming Qiu, Younghoon Nho, Robert Seilheimer, Altona Tufanoglu, David W Oslin, Katherine W Scangos, Anna Rose Childress, Casey H Halpern: Personalized Evocation of Cue-hyperreactivity May Optimize Deep Brain Stimulation for Opioid Use Disorder. American Society for Stereotactic and Functional Neurosurgery Biennial Meeting 2024.