Michael R Cook, MD

Assistant Professor of Clinical Medicine (Hematology-Oncology)
Attending, Hospital of the University of Pennsylvania
Attending , Penn Presbyterian Medical Center
Physician Lead, Inpatient Oncology Operations, Penn Presbyterian Medical Center
Department: Medicine
Contact information
Penn Presbyterian Medical Center
51 N 39th St, 1st Floor PAC building
Philadelphia, PA 19104
51 N 39th St, 1st Floor PAC building
Philadelphia, PA 19104
Office: 267-588-2569
Education:
BS (Biology: Vertebrate Physiology; Minor Psychology and Neuroscience)
Pennsylvania State University, 2013.
MD (Medicine)
Lewis Katz School of Medicine at Temple University, 2017.
Permanent linkBS (Biology: Vertebrate Physiology; Minor Psychology and Neuroscience)
Pennsylvania State University, 2013.
MD (Medicine)
Lewis Katz School of Medicine at Temple University, 2017.
Description of Clinical Expertise
Indolent B-cell Lymphoma (Follicular Lymphoma, Marginal Zone Lymphoma, Chronic lymphocytic leukemia/small lymphocytic lymphoma, lymphoplasmacytic lymphoma)Mantle Cell Lymphoma
Diffuse Large B-cell Lymphoma
Primary Mediastinal B-cell Lymphoma
Selected Publications
Jakub Svoboda, Daniel J Landsburg, James Gerson, Sunita D Nasta, Stefan K Barta, Elise A Chong, Michael Cook, Noelle V Frey, Joanne Shea, Amanda Cervini, Amy Marshall, Megan Four, Megan M Davis, Julie K Jadlowsky, Anne Chew, Edward Pequignot, Vanessa Gonzalez, Julia Han Noll, Luca Paruzzo, Juliana Rojas-Levine, Gabriela Plesa, John Scholler, Donald L Siegel, Bruce L Levine, David L Porter, Saba Ghassemi, Marco Ruella, Andrew Rech, Rachel M Leskowitz, Joseph A Fraietta, Wei-Ting Hwang, Elizabeth Hexner, Stephen J Schuster, Carl H June: Enhanced CAR T-Cell Therapy for Lymphoma after Previous Failure. The New England Journal of Medicine 18(392): 1824-1835, May 2025.Nikita K. Dave, Veronica Carvajal, Alex C. Watts, Jordan S. Carter, Michael Cook, Colin Thomas, Donald E. Tsai, Stephen J. Schuster, James N. Gerson, Stefan K. Barta, Jakub Svoboda, Elise A. Chong, Wei-Ting Hwang, Daniel J. Landsburg, Sunita D. Nasta : Outcomes at a Single Institution with MTR Induction and Consolidation in the Management of Primary CNS Lymphoma. Blood Neoplasia 2(3): 100102. April 2025 Notes: E-published on April 16, 2025.
Cook, M.R. Williams, L. Kolm, P. Dunleavy, K. : Improved Survival Outcomes for Intensive versus Standard Chemoimmunotherapy in Primary Mediastinal B-cell Lymphoma: A Meta-Analysis of 4068 Patients. Haematologica 109(3): 846-856, March 2024.
Cook, M.R, Shouval, R. Perales, M, et al. : Real-World Evidence in the United States (US) of the Impact of Bridging Therapy Prior to Axicabtagene Ciloleucel (Axi-Cel) for the Treatment of Relapsed or Refractory Large B-Cell Lymphoma (R/R LBCL). American Society of Hematology Annual Conference, San Diego, CA. Dec 2023 Notes: "Oral Presentation"
Cook, M.R. Dorris, SC. Makambi, K. Luo, Y. Munshi, P. Donato, M. Rowley, S. Saad, A. Goy, A. Dunleavy, K. Ali, A. : Toxicity and Efficacy of Chimeric Antigen Receptor (CAR) T-cell Therapy in Primary and Secondary CNS Lymphoma: A Meta-Analysis of 128 Patients. Blood Adv 7(1): 32-39, Jan 2023.
Cook, M.R. Dunleavy, K. : Targeting the Tumor Microenvironment in Lymphomas: Emerging Biological Insights and Therapeutic strategies. Current Oncology Reports 24(9): 1121-1131, Sep 2022.
Shah NJ, Cook MR, Wu T, Lev-Ari SL, Blackburn MB, Serzan MT, Alaoui A, Atkins, MB. : Association Between Immune Checkpoint Inhibitors, Corticosteroids, Immunosuppressive Agents and Opportunistic Infections. Journal of the National Comprehensive Cancer Network 20(7), July 2022.
Cook, M., Dykes, K., White, K., Desale, S., Agrawal, R., Fernandez, S., Huang, X., Cobb, N., Lai, C.: Clinical Outcomes in Patients with Hematologic Malignancy (HM) and COVID-19. Clinical Lymphoma, Myeloma & Leukemia 22(7): e452-e458. Jul 2022.
Shah NJ, Cook MR, Wu T, Lev-Ari SL, Blackburn MB, Serzan MT, Alaoui A, Atkins, MB. : The Risk of Opportunistic Infections and the Role of Antibiotic Prophylaxis in Patients on Checkpoint Inhibitors Requiring Steroids J Natl Compr Canc Netw 20(7): 800-807.e1. Jul 2022.
Zhang D, Shah NJ, Cook MR, Blackburn M, Serzan MT, Advani S, Potosky AL, Atkins MB, Braithwaite D. : Association between Body Mass Index and Immune-Related Adverse Events (irAEs) among Advanced-Stage Cancer Patients Receiving Immune Checkpoint Inhibitors: A Pan-Cancer Analysis. Cancers (Basel) 13(23): 6109, Dec 2021.