Emily Jean Onufer, MD, MPH
Assistant Professor of Surgery at the Children's Hospital of Philadelphia
Department: Surgery
Contact information
Division of Pediatric Surgery
Children's Hospital of Philadelphia
3401 Civic Center Boulevard
2d Floor, Hub Center for Clinical Collaboration
Philadelphia, PA 19104
Children's Hospital of Philadelphia
3401 Civic Center Boulevard
2d Floor, Hub Center for Clinical Collaboration
Philadelphia, PA 19104
Office: 267-455-4744
Email:
onufere@chop.edu
onufere@chop.edu
Education:
BS (Biological Engineering)
Massachusetts Institute of Technology, Cambridge, MA, 2010.
MPH
Dartmouth Institute, The Dartmouth College, Hanover, NH, 2011.
MD
Virginia Commonwealth University School of Medicine, Richmond, VA, 2015.
Permanent linkBS (Biological Engineering)
Massachusetts Institute of Technology, Cambridge, MA, 2010.
MPH
Dartmouth Institute, The Dartmouth College, Hanover, NH, 2011.
MD
Virginia Commonwealth University School of Medicine, Richmond, VA, 2015.
Selected Publications
Sescleifer AM, Onufer EJ, Greenspon J, Keller MS: A decade of firearm injuries: Children caught in the crossfire. Journal of Surgical Research 301: 259-268, Sept. 2024 Notes: Epub July 6, 2024.Di Luccia B, Molgora M, Khantakova D, Jaeger N, Chang HW, Czepielewski RS, Helmink BA, Onufer EJ, Fachi JL, Bhattarai B, Trsan T, Rodrigues PF, Hou J, Bando JK, da Silva CS, Cella M, Gilfillan S, Schreiber RD, Gordon JI, Colonna M: TREM2 deficiency reprograms intestinal macrophages and microbiota to enhance anti-PD-1 tumor immunotherapy. Science Immunology 9(95): eadi5374, May 17 2024.
Canales-Herrerias P, Uzzan M, Seki A, Czepielewski RS, Verstockt B, Livanos AE, Raso F, Dunn A, Dai D, Wang A, Al-Taie Z, Martin J, Laurent T, Ko HM, Tokuyama M, Tankelevich M, Meringer H, Cossarini F, Jha D, Krek A, Paulsen JD, Taylor MD, Nakadar MZ, Wong J, Erlich EC, Mintz RL, Onufer EJ, Helmink BA, Sharma K, Rosenstein A, Ganjian D, Chung G, Dawson T, Juarez J, Yajnik V, Cerutti A, Faith JJ, Suarez-Farinas M, Argmann C, Petralia F, Randolph GJ, Polydorides AD, Reboldi A, Colombel JF, Mehandru S: Gut-associated lymphoid tissue attrition associates with response to anti-α4β7 therapy in ulcerative colitis. Science Immunology 9(94): eadg7549, Apr. 19 2024.
Han J, Gallerand A, Erlich EC, Helmink BA, Mair I, Li X, Eckhouse SR, Dimou FM, Shakhsheer BA, Phelps HM, Chan MM, Mintz RL, Lee DD, Schilling JD, Finlay CM, Allen JE, Jakubzick CV, Else KJ, Onufer EJ, Zhang N, Randolph GJ: Human serous cavity macrophages and dendritic cells possess counterparts in the mouse with a distinct distribution between species. Nature Immunology 25(1): 155-165, Jan. 2024 Notes: Epub Dec. 15, 2023.
Onufer EJ, Czepielewski RS, Han YH, Courtney CM, Sutton S, Sescleifer A, Randolph GJ, Warner BW: Lipid absorption and overall intestinal lymphatic transport are impaired following partial small bowel resection in mice. Science Reports 12(1): 11527, July 7 2022.
Andrade EG, Onufer EJ, Thornton M, Keller MS, Schuerer DJE, Punch LJ: Racial disparities in triage of adolescent patients after bullet injury. Trauma & Acute Care Surgery 92(2): 366-370, Feb. 1 2022.
Gu W, Wang H, Huang X, Kraiczy J, Singh PNP, Ng C, Dagdeviren S, Houghton S, Pellon-Cardenas O, Lan Y, Nie Y, Zhang J, Banerjee KK, Onufer EJ, Warner BW, Spence J, Scherl E, Rafii S, Lee RT, Verzi MP, Redmond D, Longman R, Helin K, Shivdasani RA, Zhou Q: SATB2 preserves colon stem cell identity and mediates ileum-colon conversion via enhancer remodeling. Cell Stem Cell 29(1): 101-115.e10, Jan. 6 2022 Notes: Epub Sept. 27, 2021.
Czepielewski RS, Erlich EC, Onufer EJ, Young S, Saunders BT, Han YH, Wohltmann M, Wang PL, Kim KW, Kumar S, Hsieh CS, Scallan JP, Yang Y, Zinselmeyer BH, Davis MJ, Randolph GJ: Ileitis-associated tertiary lymphoid organs arise at lymphatic valves and impede mesenteric lymph flow in response to tumor necrosis factor. Immunity 54(12): 2795-2811.e9, Dec. 14 2021 Notes: Epub Nov. 16, 2021.
Zhang N, Kim SH, Gainullina A, Erlich EC, Onufer EJ, Kim J, Czepielewski RS, Helmink BA, Dominguez JR, Saunders BT, Ding J, Williams JW, Jiang JX, Segal BH, Zinselmeyer BH, Randolph GJ, Kim KW: LYVE1+ macrophages of murine peritoneal mesothelium promote omentum-independent ovarian tumor growth. Journal of Experimental Medicine 218(12): e20210924, Dec. 6 2021 Notes: Epub Oct, 29, 2021.
Han YH, Onufer EJ, Huang LH, Sprung RW, Davidson WS, Czepielewski RS, Wohltmann M, Sorci-Thomas MG, Warner BW, Randolph GJ: Enterically derived high-density lipoprotein restrains liver injury through the portal vein. Science 373(6553): eabe6729, July 23 2021.