Jacquelyn Crane, MD
Assistant Professor of Pediatrics (Oncology) at the Children's Hospital of Philadelphia
Department: Pediatrics
Contact information
The Hub for Clinical Collaboration
3500 Civic Center Blvd
Office 3547
Philadelphia, PA 19104
3500 Civic Center Blvd
Office 3547
Philadelphia, PA 19104
Education:
B.A (Psychology)
Dartmouth College, 2008.
M.D.
Tufts University School of Medicine, 2014.
Permanent linkB.A (Psychology)
Dartmouth College, 2008.
M.D.
Tufts University School of Medicine, 2014.
Description of Clinical Expertise
I am focused on the care of children with solid tumors with a particular expertise in soft tissue sarcomas.Description of Research Expertise
My research focus is in the development and oversight of early phase clinical trials for pediatric cancers.Selected Publications
Aye J, Crane J, Oberoi S: Update on Pediatric Soft Tissue Sarcomas. Curr Opin Pediatr 38(1): 53-64, February 2026.Crane JN, Xue W, Qumseya A, Barkauskas DA, Chau K, Tan SY, Hiniker S, Dasgupta R, Venkatramani R, Spunt S, Weiss AR, Laetsch TW: Malignant Peripheral Nerve Sheath Tumors in Pediatric and Young Adult Patients: A Report from Children’s Oncology Group Study ARST0332. J Natl Cancer Inst December 2025 Notes: Epub ahead of print.
Lefler DS, Nassif Haddad EF, Nohria A, Agulnik M, Crane J, Fradley MG. : Sarcoma: Cardiovascular and Oncologic Considerations. JACC CardioOncol 7(7): 800-815, December 2025.
Crane JN, Dagalakis U, Gartrell RD, Schultz KAP, Laetsch TW: Rare but not forgotten: Therapeutic advancements for rare childhood cancers. Mol Ther Oncol 33(4), November 2025.
Crane JN, Douglass DP, Oberoi S, Collins NB, Gupta A, Metts JL, Avutu V, Dela Cruz FS, Davis JL, Federman NC, Hiniker SM, Laetsch TW, Linardic CM, Navid F, Saab R, Shulman DS, Shern JF, Soragni A, Stewart EA, Terezakis S, Weigel BJ, Weiss AR: Prioritization of novel agents for further investigation in pediatric non-rhabdomyosarcoma soft tissue sarcomas: A report from the Children's Oncology Group. Eur J Cancer 226(115600), August 2025.
Jonathan L. Metts*, Jamie M. Aye*, Jacquelyn N. Crane*, Sapna Oberoi*, Frank M. Balis, Smita Bhatia, , Kira Bona, Bruce Carleton, Roshni Dasgupta, Filemon S. Dela Cruz, Katie A. Greenzang, Jonathan L. Kaufman, Corinne M. Linardic, Susan K. Parsons, Mark Robertson-Tessi, Erin R. Rudzinski, Alice Soragni, Elizabeth Stewart, Brenda J. Weigel, Suzanne L. Wolden, Aaron R. Weiss, Rajkumar Venkatramani, Christine M. Heske *co first authors: Roadmap for the Next Generation of Children’s Oncology Group Rhabdomyosarcoma Trials. Cancer 130(22): 3785-3796, Nov 2024 Notes: *co-first authors.
Hu B, Kirkey D, Wakeling A, Danielle Kirkey, McGuinness M, Kreimer S, Crane J, Spunt S: Opportunities for Improving Detection of Cancer Predisposition Syndromes in Pediatric Solid Tumor Patients. Journal of Pediatric Hematology Oncology 46(6): 311-318, Aug 2024.
Hu B, Howitt BE, Cizek S, Diver E, Hiniker S, Crane J, Daldrup-Link H, Spunt SL.: Favorable Outcome of High-grade Endometrial Stromal Sarcoma in an Adolescent. J Pediatr Hematol Oncol 46(5): e334-e337, July 2024.
Oberoi S, Crane JN, Haduong JH, RudzinskI ER, Wolden SL, Dasgupta R, Linardic CM, Weiss AR, Venkatramani R on behalf of the Children’s Oncology Group Soft Tissue Sarcoma Committee: Children’s Oncology Group’s 2023 Blueprint for Research: Soft Tissue Sarcomas. Pediatr Blood Cancer 70(6): e30556, Sep 2023.
Crane JN, Graham DS, Mona CE, Nelson SD, Samiei A, Dawson DW, Dry SM, Masri MG, Crompton JG, Benz MR, Czernin J, Eilber FC, Graeber TG, Calais J, Federman NC: Fibroblast Activation Protein Expression in Sarcomas. Sarcoma 9(1): doi: 10.1155, Jun 2023 Notes: epub.