Selected Publications

Dreishpoon MB, Bick NR, Petrova B, Warui DM, Cameron A, Booker SJ, Kanarek N, Golub TR, Tsvetkov P.: FDX1 regulates cellular protein lipoylation through direct binding to LIAS. J Biol Chem 299(9): 105046, Sep 2023.

Neti SS, Wang B, Iwig DF, Onderko EL, Booker SJ.: Enzymatic Fluoromethylation Enabled by the S-Adenosylmethionine Analog Te-Adenosyl-L-(fluoromethyl)homotellurocysteine. ACS Cent Sci 9: 905-914, May 2023.

Jiang Y, Neti SS, Sitarik I, Pradhan P, To P, Xia Y, Fried SD, Booker SJ, O'Brien EP.: How synonymous mutations alter enzyme structure and function over long timescales. Nat Chem 15(3): 308–318, March 2023.

Schulz V, Basu S, Freibert SA, Webert H, Boss L, Mühlenhoff U, Pierrel F, Essen LO, Warui DM, Booker SJ, Stehling O, Lill R.: Functional spectrum and specificity of mitochondrial ferredoxins FDX1 and FDX2. Nat Chem Biol 19(2): 206-217. February 2023.

Booker SJ, Lloyd CT.: Twenty Years of Radical SAM! The Genesis of the Superfamily. ACS Bio Med Chem Au 2: 538-547, Dec 2022.

Warui DM, Sil D, Lee KH, Neti SS, Esakova OA, Knox HL, Krebs C, Booker SJ.: In Vitro Demonstration of Human Lipoyl Synthase Catalytic Activity in the Presence of NFU1. ACS Bio Med Chem Au 2: 456-468, Oct 2022 Notes: 10.1021/acsbiomedchemau.2c00020.

Neti SS, Sil D, Warui DM, Esakova OA, Solinski AE, Serrano DA, Krebs C, Booker SJ.: Characterization of LipS1 and LipS2 from Thermococcus kodakarensis: Proteins Annotated as Biotin Synthases, which Together Catalyze Formation of the Lipoyl Cofactor. ACS Bio Med Chem Au 2: 509-520, Oct 2022.

Lloyd CT, Iwig DF, Wang B, Cossu M, Metcalf WW, Boal AK, Booker SJ.: Discovery, structure and mechanism of a tetraether lipid synthase. Nature 609: 197–203, July 2022.

Pagnier A, Balci B, Shepard EM, Yang H, Warui DM, Impano S, Booker SJ, Hoffman BM, Broderick WE, Broderick JB.: [FeFe]-Hydrogenase: Defined Lysate-Free Maturation Reveals a Key Role for Lipoyl-H-Protein in DTMA Ligand Biosynthesis. Angew Chem Int Ed Engl 61: e202203413, May 2022.

Wang B, Silakov A, Booker SJ.: Using peptide substrate analogs to characterize a radical intermediate in NosN catalysis. Methods Enzymol 666: 469-87, Mar 2022.