Selected Publications

Lei J, Markmann JF: Islet auto-transplantation for chronic pancreatitis. Cameron and Cameron Current Surgical Therapy, 15th Edition. Cameron JL, Cameron AM (eds.). Philadelphia: Elsevier, 2025 (submitted).

Liao M, Liu J, Lee KM, Tomofuji K, Tanimine N, Markmann C, Deng K, Matheson R, Yu M, Bourgeois O, Wei L, Kharga A, Yeh H, Leguern C, Deng S, Lei J, Zhao G, Markmann JF: PD-L1 on ex vivo expanded toll-like-receptor-Bregs prevents allograft rejection by targeting up-regulated PD1 on T effector cells and generating functional Tregs. American Journal of Transplantation 2024 (submitted).

Zhang L, Song S, Li C, Zhu N, Yang M, Huang W, Lei J, Li G, Jiapaer Z: The bacterial microbiome and infertility. Reproductive Biology & Endocrinology 2024 (in press).

Cheng H, Hua L, Tang H, Bao Z, Xu X, Zhu H, Wang S, Jiapaer Z, Bhatia R, Dunn IF, Deng J, Wang D, Sun S, Luan S, Ji J, Xie Q, Yang X, Lei J, Li G, Wang X, Gong Y: CBX7 reprograms metabolic flux to protect against meningioma progression by modulating the USP44/c-MYC/LDHA axis. Journal of Molecular & Cellular Biology 15(10): mjad057, Apr. 4 2024 Notes: Epub Oct. 3, 2023.

Lei J, Markmann JF: Clinical trials with stem cell-derived insulin-producing cells. Pluripotent Stem Cell Therapy for Diabetes. Piemonti L, Odorico J, Kieffer TJ, Sordi V, de Koning E (eds.). New York: Springer-Nature, Page: 547-571, 2024.

Sremac M, Luo H, Deng H, Parr MFE, Hutcheson J, Verde PS, Alagpulinsa DA, Kitzmann JM, Papas KK, Brauns T, Markmann JF, Lei J, Poznansky MC: Short-term function and immune-protection of microencapsulated adult porcine islets with alginate incorporating CXCL12 in healthy and diabetic non-human primates without systemic immune suppression: A pilot study. Xenotransplantation 30(6): e12826, Nov./Dec. 2023 Notes: Epub Sept. 15, 2023.

Lei J, Deng HD, Yolcu E, Shirwan H, García A, Markmann J: Bioengineered omental transplant site promotes islet/cell survival in non-human primates. Transplantation 107(10 Suppl 2): 4, Oct. 2023 Notes: Presented at the International Pancreas & Islet Transplant Association/International Xenotransplantation Association/Cell Transplant & Regenerative Medicine (IPITA-IXA-CTRMS) Congress, San Diego, CA, Oct. 2023.

Deng H, Zhang A, Pan D, Yang Z, Lee K, Matheson R, Rosales I, Coronel M, Yolcu E, Shirwan H, Garcia A, Markmann JF, Lei J: Allogeneic pancreatic islets transplanted to a bioengineered omentum achieves euglycemic control in a diabetic non-human primate model. Oral presentation at the American Transplant Congress (ATC) 2023, San Diego, CA June 2023.

Fu Q, Lee KM, Deng K, Liao M, Lei J, Zhao G, Yang H, LeGuern C, Deng S, Markmann JF: Influence of TNF-α on in vitro induced regulatory B cells. Oral presentation at the American Transplant Congress (ATC) 2023, San Diego, CA June 2023.

Deng H, Zhang A, Pang DRR, Xi Y, Yang Z, Matheson R, Li G, Luo H, Lee KM, Fu Q, Zou Z, Chen T, Wang Z, Rosales IA, Peters CW, Yang J, Coronel MM, Yolcu ES, Shirwan H, García AJ, Markmann JF, Lei J: Bioengineered omental transplant site promotes pancreatic islet allografts survival in non-human primates. Cell Reports Medicine 4(3): 100959, Mar. 21 2023 Notes: Epub Mar. 1, 2023; This work garnered significant attention and has been widely reported through various media channels, including MGH news releases, social media, internet news outlets, and podcasts.