Selected Publications

Chia R, Moaddel R, Kwan JY, Rasheed M, Ruffo P, Landeck N, Reho P, Vasta R, Calvo A, Moglia C, Canosa A, Manera U, Snyder A, Saez-Atienzar S, Grassano M, Brunetti M, Casale F, Ray A, Arvind K, Comertpay B, Zhu M, Gibbs JR; American Genome Center; Alba C, Dawson TM, Rosenthal LS, Hall AJ, Pantelyat AY, Narendra DP, Ehrlich DJ, Walker KA, Kosa P, Bielekova B, Egan JM, Candia J, Tanaka T, Ferrucci L, Dalgard CL, Scholz SW, Chiò A, Traynor BJ.: A plasma proteomics-based candidate biomarker panel predictive of amyotrophic lateral sclerosis. Nat Med Aug 2025.

Boyle R, Dehghani N, Emrani S, Wadhwani AR, Matyi M, Cousins KAQ, Rhodes E, Nelson B, Stites SD, Xie SX, Dratch L, Van Deerlin VM, Snyder A, Irwin D, McMillan CT, Massimo L.: Neighborhood deprivation moderates prognosis in behavioral-variant frontotemporal degeneration. medRxiv May 2025.

Sheth U, Öijerstedt L, Heckman MG, White LJ, Heuer HW, Lario Lago A, Forsberg LK, Faber KM, Foroud TM, Rademakers R, Ramos EM, Appleby BS, Bozoki AC, Darby RR, Dickerson BC, Domoto-Reilly K, Galasko DR, Ghoshal N, Graff-Radford NR, Grant IM, Hales CM, Hsiung GR, Huey ED, Irwin D, Kwan JY, Litvan I, Mackenzie IR, Masdeu JC, Mendez MF, Onyike CU, Pascual B, Pressman PS, Roberson ED, Snyder A, Tartaglia MC, Seeley WW, Dickson DW, Rosen HJ, Boeve BF, Boxer AL, Petrucelli L, Gendron TF.: Comprehensive cross-sectional and longitudinal comparisons of plasma glial fibrillary acidic protein and neurofilament light across FTD spectrum disorders. Mol Neurodegener 20: 30, Mar 2025.

Dykstra MM, Weskamp K, Gómez NB, Waksmacki J, Tank E, Glineburg MR, Snyder A, Pinarbasi E, Bekier M, Li X, Miller MR, Bai J, Shahzad S, Nedumaran N, Wieland C, Stewart C, Willey S, Grotewold N, McBride J, Moran JJ, Suryakumar AV, Lucas M, Tessier PM, Ward M, Todd PK, Barmada SJ.: TDP43 autoregulation gives rise to dominant negative isoforms that are tightly controlled by transcriptional and post-translational mechanisms. Cell Rep 44: 115113, Jan 2025.

Saloner R, Staffaroni AM, Dammer EB, Johnson ECB, Paolillo EW, Wise A, Heuer HW, Forsberg LK, Lario-Lago A, Webb JD, Vogel JW, Santillo AF, Hansson O, Kramer JH, Miller BL, Li J, Loureiro J, Sivasankaran R, Worringer KA, Seyfried NT, Yokoyama JS, Spina S, Grinberg LT, Seeley WW, VandeVrede L, Ljubenkov PA, Bayram E, Bozoki A, Brushaber D, Considine CM, Day GS, Dickerson BC, Domoto-Reilly K, Faber K, Galasko DR, Gendron T, Geschwind DH, Ghoshal N, Graff-Radford N, Hales CM, Honig LS, Hsiung GR, Huey ED, Kornak J, Kremers W, Lapid MI, Lee SE, Litvan I, McMillan CT, Mendez MF, Miyagawa T, Pantelyat A, Pascual B, Masdeu J, Paulson HL, Petrucelli L, Pressman P, Rademakers R, Ramos EM, Rascovsky K, Roberson ED, Savica R, Snyder A, Sullivan AC, Tartaglia MC, Vandebergh M, Boeve BF, Rosen HJ, Rojas JC, Boxer AL, Casaletto KB; ALLFTD Consortium.: Large-scale network analysis of the cerebrospinal fluid proteome identifies molecular signatures of frontotemporal lobar degeneration. Nat Aging 2025.

Morrow CB, Kamath V, Dickerson BC, Eldaief M, Rezaii N, Wong B, McGinnis S, Darby R, Staffaroni AM, Lapid MI, Pascual B, Rojas JC, Masdeu JC, Tsapkini K, Huey ED, Fisher DW, Pantelyat A, Balaji A, Sah E, Litvan I, Rascovsky K, Ghoshal N, Domoto-Reilly K, Kornak J, Onyike CU; ALLFTD Consortium.: Neuropsychiatric symptoms cluster and fluctuate over time in behavioral variant frontotemporal dementia. Psychiatry Clin Neurosci 2025.

Memel M, Staffaroni AM, Ilan-Gala I, Castro JG, Kornak J, Tartaglia CM, Saloner R, VandeBunte AM, Paolillo EW, Cadwallader CJ, Chen C, Gorno-Tempini ML, Mandelli M, Apostolova L, Graff-Radford N, Litvan I, Bayram E, Pressman PS, Miyagawa T, Mackenzie I, Goldman J, Darby RR, Appleby BS, Petrucelli L, Gendron T, Heuer HW, Forseberg LK, Rojas JC, Boeve BF, Brushaber N, Domoto-Reilly K, Ghoshal N, Lapid M, Pascual B, Lee S, Ramos EM, Ramanan V, Rademakers R, Rascovsky K, Pantelyat A, Masdeu JC, Snyder A, Boxer AL, Rosen HJ, Casaletto K; ALLFTD Consortium.: Sex differences in the clinical manifestation of autosomal dominant frontotemporal dementia. Alzheimers Dement 2025.

Vandebergh M, Ramos EM, Corriveau-Lecavalier N, Ramanan VK, Kornak J, Mester C, Kolander T, Brushaber DE, Staffaroni AM, Geschwind DH, Wolf AA, Kantarci K, Gendron T, Petrucelli L, Van den Broeck M, Wynants S, Baker M, Borrego-Écija S, Appleby B, Barmada S, Bozoki AC, Clark D, Darby RR, Dickerson BC, Domoto-Reilly K, Fields JA, Galasko D, Ghoshal N, Graff-Radford NR, Grant IM, Honig LS, Hsiung GR, Huey ED, Irwin DJ, Knopman DS, Kwan JY, Léger GC, Litvan I, Masdeu JC, Mendez MF, Onyike CU, Pascual B, Pressman PS, Ritter A, Roberson ED, Snyder A, Sullivan AC, Tartaglia MC, Wint D, Heuer HW, Forsberg LK, Boxer AL, Rosen HJ, Boeve BF, Rademakers R; ALLFTD Consortium.: Gene-Specific Effects on Brain Volume and Cognition of TMEM106B in Frontotemporal Lobar Degeneration. Neurology 103: e209832, Oct 2024.

Snyder A, Ryan VH, Hawrot J, Lawton S, Ramos DM, Qi YA, Johnson K, Reed X, Johnson NL, Kollasch AW, Duffy M, Vandevrede L, Cochran JN, Miller BL, Toro C, Bielekova B, Yokoyama JS, Marks DS, Kwan JY, Cookson MR, Ward ME: An ANXA11 P93S variant dysregulates TDP-43 and causes corticobasal syndrome. Alzheimer's and Dementia 8: 5220-5235, Aug 2024.

VandeBunte AM, Lee H, Paolillo EW, Hsiung GR, Staffaroni AM, Saloner R, Tartaglia C, Yaffe K, Knopman DS, Ramos EM, Rascovsky K, Bozoki AC, Wong B, Domoto-Reilly K, Snyder A, Pressman P, Mendez MF, Litvan I, Fields JA, Galasko DR, Darby R, Masdeu JC, Pasqual MB, Honig LS, Ghoshal N, Appleby BS, Mackenzie IR, Heuer HW, Kramer JH, Boxer AL, Forsberg LK, Boeve B, Rosen HJ, Casaletto KB; ALLFTD Consortium.: Better cardiovascular health is associated with slowed clinical progression in autosomal dominant frontotemporal lobar degeneration variant carriers. Alzheimers Dement 2024.