Carman M Li, Ph.D.

Assistant Professor of Cancer Biology
Assistant Investigator, Abramson Family Cancer Research Institute
Core Investigator, The Basser Center for BRCA
Department: Cancer Biology
Publications
Links
Search PubMed for articles
Abramson Family Cancer Research Institute faculty page
Department of Cancer Biology faculty page
Carman Li Lab website
Search PubMed for articles
Abramson Family Cancer Research Institute faculty page
Department of Cancer Biology faculty page
Carman Li Lab website
Education:
A.B. (Molecular Biology, High Honors)
Princeton University, 2009.
Ph.D. (Biology)
Massachusetts Institute of Technology, 2015.
Permanent linkA.B. (Molecular Biology, High Honors)
Princeton University, 2009.
Ph.D. (Biology)
Massachusetts Institute of Technology, 2015.
Selected Publications
Li CM#, Cordes A, Oliphant M, Quinn SA, Thomas M, Selfors LM, Silvestri F, Zoeller JJ, Shapiro H, Tsiobikas C, Gupta K, Pathania S, Regev A, Kadoch C, Muthuswamy SK, Brugge JS# (# co-corresponding authors) : Brca1 haploinsufficiency promotes early tumor onset and epigenetic alterations in a mouse model of hereditary breast cancer. Nature Genetics 56(12): 2763-2775, November 2024.Gray, GK*, Li, CM*, Rosenbluth, JM*, Selfors, LM*, Girnius, N, Lin, J-R, Schackmann, RCJ, Goh, WL, Moore, K, Shapiro, HK, Mei, S, D’Andrea, K, Nathanson, KL, Sorger, PK, Santagata, S, Regev, A, Garber, JE, Dillon, DA, Brugge, JS (* co-first authors, alphabetical): A human breast atlas integrating single-cell proteomics and transcriptomics. Developmental Cell 57(11): 1400-1420.e7, June 2022.
Rauner, G, Jin, DX, Miller, DH, Gierahn, TM, Li, CM, Sokol, ES, Feng, Y-X, Mathis, RA, Love, JC, Gupta, PB, Kuperwasser, C.: Breast tissue regeneration is driven by cell-matrix interactions coordinating multi-lineage stem cell differentiation through DDR1. Nature Communications 12(1): 7116, December 2021.
Li, CM, Shapiro, H, Tsiobikas, C, Selfors, LM, Chen, H, Rosenbluth, J, Moore, K, Gupta, KP, Gray, GK, Oren, Y, Steinbaugh, MJ, Guerriero, JL, Pinello, L, Regev, A, Brugge, JS.: Aging-associated alterations in mammary epithelia and stroma revealed by single-cell RNA sequencing, Cell Reports 33(13): 108566, December 2020.
Rosenbluth, JM, Schackmann, RCJ, Gray, GK, Selfors, LM, Li, CM, Boedicker, M, Kuiken, HJ, Richardson, A, Brock, J, Garber, J, Dillon, D, Sachs, N, Clevers, H, Brugge, JS.: Organoid cultures from normal and cancerprone human breast tissues preserve complex epithelial lineages. Nature Communications 11(1): 1711-14, April 2020.
Hamza, B, Ng, SR, Prakadan, SM, Delgado, FF, Chin, CR, King, EM, Yang, LF, Davidson, SM, DeGouveia, KL, Cermak, N, Navia, AW, Winter, PS, Drake, RS, Tammela, T, Li, CM, Papagiannakopoulos, T, Gupta, AJ, Bagnall, JS, Knudsen, SM, Heiden, MGV, Wasserman, SC, Jacks, T, Shalek, AK, Manalis, SR.: Optofluidic real-time cell sorter for longitudinal CTC studies in mouse models of cancer. PNAS 116(6): 2232-2236, February 2019.
Gocheva, V, Naba, A, Bhutkar, A, Guardia, T, Miller, KM, Li, CM, Dayton, TL, Sanchez-Rivera, FJ, Kim-Kiselak, C, Jailkhani, N, Winslow, MM, Rosario, AD, Hynes, RO, Jacks, T.: Quantitative proteomics identify Tenascin-C as a promoter of lung cancer progression and contributor to a signature prognostic of patient survival. PNAS 40(28): 201707054-E5634, July 2017.
Muzumdar, MD, Dorans, KJ, Chung, KM, Robbins, R, Tammela, T, Gocheva, V, Li, CM, Jacks, T.: Clonal dynamics following p53 loss of heterozygosity in Kras-driven cancers. Nature Communications 7(1): 12685, September 2016.
Li, CM, Gocheva, V, Oudin, MJ, Bhutkar, A, Wang, SY, Date, SR, Ng, SR, Whittaker, CA, Bronson, RT, Snyder, EL, Gertler, FB, Jacks, T.: Foxa2 and Cdx2 cooperate with Nkx2-1 to inhibit lung adenocarcinoma metastasis. Genes & Development 29(17): 1850-1862, September 2015.
Yu B-B, Moffatt BE, Fedorova M, Villiers CGS, Arnold JN, Du E, Swinkels A, Li CM, Ryan A, Sim RB: Purification, Quantification, and Functional Analysis of Complement Factor H. Methods in Molecular Biology 1100: 207–223, October 2013.