Jena Miller, MD
Associate Professor of Surgery at the Children's Hospital of Philadelphia
Co-Director & Chief, Center for Fetal Diagnosis and Treatment, Children's Hospital of Philadelphia
Department: Surgery
Contact information
Children's Hospital of Philadelphia
The Center for Fetal Diagnosis and Treatment
3401 Civic Center Boulevard
Philadelphia, PA 19104
The Center for Fetal Diagnosis and Treatment
3401 Civic Center Boulevard
Philadelphia, PA 19104
Office: 215-590-5190
Fax: 215-590-2447
Fax: 215-590-2447
Education
AA
University of Florida, Gainesville, FL, 1996.
BS (Biology)
University of North Florida, Jacksonville, FL, 1998.
MD
University of Miami Miller School of Medicine, Miami, FL, 2003.
Permanent linkAA
University of Florida, Gainesville, FL, 1996.
BS (Biology)
University of North Florida, Jacksonville, FL, 1998.
MD
University of Miami Miller School of Medicine, Miami, FL, 2003.
Description of Clinical Expertise
I have specialized expertise in treatment and intervention for complex fetal conditions. I am one of few maternal fetal surgeons in the country that can perform the full scope of in-utero intervention including ultrasound guided needle procedures, operative fetoscopy, and open fetal surgery who receives referrals from across the country. Based on my clinical expertise, I have become a national leader within this niche as evidenced by invited presentations and publications as well as contribution to national society consensus statements.Description of Research Expertise
My scientific research focus centers around using ultrasound for fetal diagnosis and management of complicated pregnancies that are amenable for fetal interventions. I also have unique experience in modeling and simulation and this provided the foundation for developing a technique for rapid prototyping for 3D printed patient-matched modeling for fetal spina bifida surgery. I have grown into an independent investigator and collaborator with both NIH funded and unfunded multiple ongoing multi-center fetal surgery focused studies. I serve as a Co-principal investigator for a NIH-funded multi-center fetal intervention trial, Co-investigator for translational research regarding stem cells for future fetal interventions, and principal investigator for an industry sponsored multi-center international trial investigating a new drug for preventing fetal anemia.Selected Publications
Miller JL, Baschat AA, Johnson A, Blumenfeld YJ, Schenone MH, Gebb JS, Moldenhauer JS, Zaretsky MV, Chmait RH, Gonzalez JM, Miller RS, Krispin E, Shamshirsaz A, Bligard KH, Kalan AM, Sanz Cortes M, Moon-Grady AJ, Bendel-Stenzel E, Menon S, Wong C, Grimm P, Kwak C, Gallup J, McKenna KJ, Marron L, Hanna C, Tran CL, Behrendt NJ, Galan HL, Samuels J, Swinford R, Keiser AM, Rosner M, Kush ML, Nasr I, Vasu S, Boss RD, Jelin AC, Thompson RE, Davis JM, Warren DS, Hanley DF, Atkinson MA.: Neonatal Survival After Serial Amnioinfusions for Anhydramnios Due to Fetal Kidney Failure: The RAFT Clinical Trial. JAMA 336: 473-483, Aug 2026.Taleb M, Miller JL, Atkinson MA, Baschat AA, Rosner M, Blumenfeld YJ, Moldenhauer JS, Gebb JS, Johnson A, Schenone MH, Zaretsky MV, Chmait RH, Gonzalez JM, Miller RS, Jelin AC, Davis JM, Warren DS, Hanley DF, Moon-Grady AJ.: Fetal Echocardiography and Hyperoxia Testing after Serial Amnioinfusions: Results from the RAFT Trial Bilateral Renal Agenesis Arm. Fetal Diagn Ther Jul 2026.
Hersh DS, Anuar A, Bennett KA, Clifford CM, Elbabaa SK, Emery SP, Goodnight WH, Hirose S, Jampa A, Lillegard JB, Lim FY, Luks FI, Miller JL, Moehrlen U, Moldenhauer JS, Schenone MH, Shaaban AF, Tsao K, Zaretsky MV, Crombleholme TM: fMMC Consortium sponsored by NAFTNet (North American Fetal Therapy Network) Fetal Myelomeningocele Closure in the Setting of Maternal Body Mass Index 35 to 40. Neurosurgery June 2026 Notes: 1;98(6):1278-1287. doi: 10.1227/neu.0000000000003802. Epub 2025 Oct 17.
Shantz CF, Dit Nasrallah KI, Miller JL, Jiang-Yu A, Varthaliti A, Millard S, Kush ML, Baschat AA, Rosner M.: Twin Anemia Polycythemia Sequence: Pretreatment Characteristics and Outcomes Stratified by Management Approach. Prenat Diagn Jun 2026.
Taylor ER, Miller JL, Rivera C, Varthaliti A, Johnson J, Kush ML, Baschat AA, Rosner M.: Corrigendum to Middle cerebral artery Doppler velocity discordance in the first 2 weeks after laser for twin-twin transfusion syndrome. American Journal of Obstetrics & Gynecology 8(5), May 2026.
Alan JT, Meiss LN, Miller JL, Kush M, Jelin AC, Baschat AA, Rosner M.: Monochorionic, Dizygotic, Sex Discordant Twins With Twin Anemia Polycythemia Sequence. American Journal of Medical Genetics Part A Feb 2026 Notes: 200(2):518-520. doi: 10.1002/ajmg.a.64278. Epub 2025 Oct 11.
Hersh DS, Anuar A, Anadkat J, Bennett KA, Blumenfeld YJ, Buchanan CQ, Clifford CM, Emery SP, Gebb JS, Goodnight WH, Herzeg A, Heuer GG, Hirose S, Jampa A, Lillegard JB, Lim FY, Luks FI, Miller JL, Moehrlen U, Moldenhauer JS, Cortes MS, Schenone MH, Shaaban AF, Tsao K, Van Mieghem T, Wagner AJ, Zaretsky MV, Crombleholme TM: fMMC Consortium sponsored by NAFTNet (North American Fetal Therapy Network) Prenatal Closure of Myeloschisis vs Myelomeningocele: Insights From the fMMC Consortium Registry. Neurosurgery. Feb 2026 Notes: doi: 10.1227/neu.0000000000003954. Epub ahead of print.
Taylor ER, Miller JL, Rivera C, Varthaliti A, Johnson J, Kush ML, Baschat AA, Rosner M.: Middle cerebral artery Doppler velocity discordance in the first 2 weeks after laser for twin-twin transfusion syndrome. Am J Obstet Gynecol MFM Feb 2026.
Zargarzadeh N, Rojhani E, Javinani A, Abiad M, Sambatur E, Krispin E, Premkumar A, Chmait RH, Papanna R, Miller JL, Aagaard K, Shamshirsaz AA.: Maternal outcomes following prenatal spina bifida repair: A systematic review and meta-analysis. Pregnancy (Hoboken) 2: e70230, Jan 2026.
Williams KV, Rosner M, Shantz C, Taylor E, Satin AJ, Kush M, Miller J, Baschat AA: Sociodemographic factors and perinatal outcomes after laser surgery for twin-twin transfusion syndrome: A retrospective cohort study. BJOG June 13 2025 (Epub) Notes: doi: 10.1111/1471-0528.18248.