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John V. Bosso, M.D., FAAAAI

Professor of Clinical Otorhinolaryngology: Head and Neck Surgery
Attending Physician, Clinical Professor, Hospital of the University of Pennsylvania
Director, Otorhinolaryngology: HNS Allergy Clinic, Department of Otorhinolaryngolgy: Head and Neck Surgery at the Perelman Center for Advanced Medicine, Hospital of the University of Pennsylvania
Medical Director, Penn AERD Center, Department of Otorhinolaryngology: Head and Neck Surgery at the Perelman Center for Advanced Medicine, Hospital of the University of Pennsylvania
Department: Otorhinolaryngology: Head and Neck Surgery

Contact information
Hospital of the University of Pennsylvania
Perelman Center for Advanced Medicine
South Pavilion, 3rd Floor
3400 Civic Center Boulevard
Philadelphia, PA 19104
Office: 215-360-0372
Fax: 215-662-4613
Education:
B.S. (Biochemistry, summa cum laude)
Saint Peter's University, Jersey City, New Jersey, 1981.
M.D. (Medicine)
Jacobs School of Medicine, University at Buffalo, Buffalo, New York, 1985.
Post-Graduate Training
Internal Medicine Residency, SUNY Downstate at Staten Island University Hospital, 1985-1988.
Clinical Fellowship, Allergy/Immunology, Scripps Clinic and Research Foundation, La Jolla, California, 1988-1990.
Certifications
Diplomate, National Board of Medical Examiners , 1986.
Diplomate, American Board of Internal Medicine , 1988.
Diplomate, American Board of Allergy & Immunology, Actively participating in MOC, 1991.
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Description of Clinical Expertise

AERD/Samter's Triad
Chronic Rhinosinusitis
Nasal polyps
Aspirin/NSAID Allergy
Aspirin Desensitization
Biologicals for Asthma, CRS, Nasal Polyps
Immunotherapy for Allergic Diseases

Description of Research Expertise

AERD/Samter's Triad
Chronic Rhinosinusitis
Nasal polyps
Aspirin/NSAID Allergy
Aspirin Desensitization
Biologicals for Asthma, CRS, Nasal Polyps
Immunotherapy

Selected Publications

Sell EA, Tan LH, Renner DM, Douglas J, Lee RJ, Kohanski MA, Bosso JV, Kennedy DW, Palmer JN, Adappa ND, Weiss SR, Cohen NA.: Common Cold Coronavirus 229E Induces Higher Interferon Stimulating Gene Responses in Human Nasal Epithelial Cells from Patients with Chronic Rhinosinusitis with Polyposis. Am J Rhinol Allergy 39(1): 13-20, Jan 2025.

Asthana S, Workman AD, Lerner DK, Randell RM, Lopez DF, Kohanski MA, Palmer JN, Adappa ND, Douglas JE, Bosso JV.: Social factors associated with aspirin desensitization and diagnosis age in aspirin-exacerbated respiratory disease. Int Forum Allergy Rhinol. Timothy Smith. MD (eds.). Wiley, 15(1): 89-92, Jan 2025.

Workman AD, Kuppusamy K, Lerner DK, Bosso JV, Douglas JE, Kohanski MA, Adappa ND, Palmer JN. : Assessing adequacy of surgical extent in CRSwNP: The Completion of Surgery Index. Int Forum Allergy Rhinol. Timothy Smith. MD (eds.). Wiley, 15(1): 9-17, Jan 2025.

Jessica Migala: The Little-Known Side Effect of Aspirin Asthma Sufferers Need to Know About AARP Health Online. AARP, April 2024.

Workman Ad, Chang J, Lerner DK, Wilensky J, Montone KT, Bosso JV, Palmer JN, Adappa ND, Kohanski MA. : "Utilizing Histopathology to Predict Success with Macrolide Therapy in CRS Patients". Laryngoscope. 134(3): 1003-1004, March 2024.

Kohanski MA, Qatanani A, Lin C, Tan LH, Chang J, Corr A, Herzberg S, Adappa ND, Palmer JN, Reed DR, Bosso JV, Cohen NA: Long-term aspirin desensitization has mucosal cytokine features of immune tolerance. Allergy 79(2): 507-509, Feb 2024.

Buckey TM, Bosso JV: "A Stepwise Approach to the adult immunodeficiency evaluation for the rhinologist". Curr Opin Otolaryngol Head Neck Surg 32(1): 50-54, Feb 2024.

Herzberg SD, Bosso AM, Sangal NR, Bosso JV: Eosinophilic granulomatosis with polyangiitis presenting as aspirin-exacerbated respiratory disease. Ann Allergy Asthma Immunol. M.Grayson (eds.). Science Direct, 131(4): 528-530, October 2023.

Lee DJ, Cramer HB, Kshirsagar RS, Douglas JE, Kohanski, MA, Palmer JN, Adappa ND, Bosso JV.: Dupilumab-related adverse events among patients with chronic rhinosinusitis with nasal polyposis. Int Forum Allergy Rhinol. T Smith (eds.). Wiley, 13(8): 1542-1545, August 2023.

Panara K, Grose E, Lee DJ, Safadi J, Douglas JE, Kohanski MA, Palmer JN, Lee JM, Adappa ND, Bosso JV : Readability and quality analysis of patient education materials in aspirin-exacerbated respiratory disease. Int Forum Allergy Rhinol. T Smith (eds.). Wiley, June 2023 Notes: online ahead of print.

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Last updated: 03/14/2025
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