John V. Bosso - Faculty Biosketch

John V. Bosso, M.D., FAAAAI

Professor of Clinical Otorhinolaryngology: Head and Neck Surgery

Attending Physician, Clinical Professor, Hospital of the University of Pennsylvania

Director, Otorhinolaryngology: HNS Allergy Clinic, Department of Otorhinolaryngolgy: Head and Neck Surgery at the Perelman Center for Advanced Medicine, Hospital of the University of Pennsylvania

Medical Director, Penn AERD Center, Department of Otorhinolaryngology: Head and Neck Surgery at the Perelman Center for Advanced Medicine, Hospital of the University of Pennsylvania

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Department: Otorhinolaryngology: Head and Neck Surgery

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46 Contact information
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Hospital of the University of Pennsylvania
2d Perelman Center for Advanced Medicine
21 South Pavilion, 3rd Floor
3e 3400 Civic Center Boulevard
Philadelphia, PA 19104

2e Office: 215-360-0372
32 Fax: 215-662-4613
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Links
ac Penn AERD Center
79 Penn Medicine Profile
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13 Education:
21 9 B.S. 2a (Biochemistry, summa cum laude) c
4a Saint Peter's University, Jersey City, New Jersey, 1981.
21 9 M.D. 15 (Medicine) c
5c Jacobs School of Medicine, University at Buffalo, Buffalo, New York, 1985.
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1f Post-Graduate Training
24 6e Internal Medicine Residency, SUNY Downstate at Staten Island University Hospital, 1985-1988.
24 83 Clinical Fellowship, Allergy/Immunology, Scripps Clinic and Research Foundation, La Jolla, California, 1988-1990.
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17 Certifications
28 48 Diplomate, National Board of Medical Examiners , 1986.
28 48 Diplomate, American Board of Internal Medicine , 1988.
28 37 Diplomate, American Board of Allergy & Immunology, 33 Actively participating in MOC, 1991.
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3 8d Permanent link
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b6 > Perelman School of Medicine > Faculty > Details a

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Description of Clinical Expertise

24 AERD/Samter's Triad
1e Chronic Rhinosinusitis
14 Nasal polyps
1d Aspirin/NSAID Allergy
1f Aspirin Desensitization
31 Biologicals for Asthma, CRS, Nasal Polyps
2a Immunotherapy for Allergic Diseases
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Description of Research Expertise

24 AERD/Samter's Triad
1e Chronic Rhinosinusitis
14 Nasal polyps
1d Aspirin/NSAID Allergy
1f Aspirin Desensitization
31 Biologicals for Asthma, CRS, Nasal Polyps
14 Immunotherapy
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Selected Publications

164 Yu AJ, Phung C, Kuppusamy K, Finuoli AM, Espinosa MC, Douglas JE, Kohanski MA, Adappa ND, Cohen NA, Bosso JV, Palmer JN, Workman AD.: The Completeness of Surgery Index Predicts Success in CRSwNP With Asthma by SNOT-22 and Asthma Control Test. Int Forum Allergy Rhinol October 2025.

172 Herpin LP, Finuoli AM, Workman AD, Tang SH, Kuppusamy K, Kohanski MA, Palmer JN, Adappa ND, Douglas JE, Bosso JV. : Factors Influencing Aspirin Therapy after Desensitization (ATAD) Tolerance in Aspirin-Exacerbated Respiratory Disease (AERD) Patients. Ann Allergy Asthma Immunol. Septemeber 2025.

12e Douglas JE, Tang SH, Mani A, Palmer JN, Adappa ND, Kohanski MA, Bosso JV.: Institutional Experience in Aspirin-Exacerbated Respiratory Disease Yields Favorable Pulmonary and Sinonasal Outcomes. Ear Nose Throat Journal July 2025.

19e Sell EA, Tan LH, Renner DM, Douglas J, Lee RJ, Kohanski MA, Bosso JV, Kennedy DW, Palmer JN, Adappa ND, Weiss SR, Cohen NA.: Common Cold Coronavirus 229E Induces Higher Interferon Stimulating Gene Responses in Human Nasal Epithelial Cells from Patients with Chronic Rhinosinusitis with Polyposis. Am J Rhinol Allergy 39(1): 13-20, Jan 2025.

184 Asthana S, Workman AD, Lerner DK, Randell RM, Lopez DF, Kohanski MA, Palmer JN, Adappa ND, Douglas JE, Bosso JV.: Social factors associated with aspirin desensitization and diagnosis age in aspirin-exacerbated respiratory disease. Int Forum Allergy Rhinol. Timothy Smith. MD (eds.). Wiley, 15(1): 89-92, Jan 2025.

14d Workman AD, Kuppusamy K, Lerner DK, Bosso JV, Douglas JE, Kohanski MA, Adappa ND, Palmer JN. : Assessing adequacy of surgical extent in CRSwNP: The Completion of Surgery Index. Int Forum Allergy Rhinol. Timothy Smith. MD (eds.). Wiley, 15(1): 9-17, Jan 2025.

8e Jessica Migala: The Little-Known Side Effect of Aspirin Asthma Sufferers Need to Know About 3e AARP Health Online. AARP, April 2024.

134 Workman Ad, Chang J, Lerner DK, Wilensky J, Montone KT, Bosso JV, Palmer JN, Adappa ND, Kohanski MA. : "Utilizing Histopathology to Predict Success with Macrolide Therapy in CRS Patients". Laryngoscope. 134(3): 1003-1004, March 2024.

100 Kohanski MA, Qatanani A, Lin C, Tan LH, Chang J, Corr A, Herzberg S, Adappa ND, Palmer JN, Reed DR, Bosso JV, Cohen NA: Long-term aspirin desensitization has mucosal cytokine features of immune tolerance. 3a Allergy 79(2): 507-509, Feb 2024.

ef Buckey TM, Bosso JV: "A Stepwise Approach to the adult immunodeficiency evaluation for the rhinologist". Curr Opin Otolaryngol Head Neck Surg 32(1): 50-54, Feb 2024.

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26 Last updated: 10/13/2025
34 The Trustees of the University of Pennsylvania c