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Melissa S Xanthopoulos

Associate Professor of Clinical Psychiatry
Co-Leader of Continuous Positive Airway Pressure Quality Improvement Initiative, Children's Hospital of Philadelphia
Department: Psychiatry

Contact information
Children’s Hospital of Philadelphia
The Sleep Center
34th and Civic Center Boulevard, 9 NW 50
Philadelphia, PA 19104
BS (Kinesiology, Minor in Psychology)
Pennsylvania State University , 1998.
MS (Clinical Exercise Physiology)
East Stroudsburg University, 1999.
MS (Clinical Psychology-Health Psychology)
Drexel University , 2003.
PhD (Clinical Psychology)
Drexel University , 2006.
Post-Graduate Training
Clinical Intern, Clinical Psychology Training Consortium, Alpert Medical School of Brown University Child/Pediatric Psychology Specialization , 2005-2006.
Postdoctoral Fellow, Center for Obesity Research and Education and Department of Kinesiology, Temple University, 2006-2007.
Permanent link
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Description of Clinical Expertise

pediatric obstructive sleep apnea
positive airway pressure
pediatric obesity assessment and interventions
lifestyle interventions
health behavior change

Description of Other Expertise

quality improvement

Description of Research Expertise

lifestyle interventions
health behavior change
pediatric obstructive sleep apnea
positive airway pressure
pediatric obesity
neurodevelopmental differences
physical activity

Selected Publications

Tsou, PY; Cielo C; Xanthopoulos M; Wang YH; Kuo PL; Tapia I.: The Burden of Obstructive Sleep Apnea in Pediatric Sickle Cell Disease: a Kids' Inpatient Database Study. Sleep 44(2), Feb 2021.

Cielo C, Hernandez P, Ciampaglia A, Xanthopoulos MS, Beck SE, Tapia IE. : Efficacy of positive airway pressure for the treatment of obstructive sleep apnea syndrome in infants. CHEST 159(2): 810-817, Feb 2021.

Tsou PY, Cielo C, Xanthopoulos M, Wang YH, Kuo PL, Tapia I.: Impact of Obstructive Sleep Apnea on Assisted Ventilation in Children with Asthma Exacerbation Pediatric Pulmonology Jan 2021 Notes: doi: 10.1002/ppul.25247. Online ahead of print.

Xanthopoulos, MS: Battling Mental Fatigue. Health Tip of the Week. https://www.chop.edu/news/health-tip/battling-mental-fatigue Nov 2020.

Xanthopoulos MS, Benton T., Lewis, J., Case JA, Master CL.: Mental health concerns of the young athlete. Current Psychiatry Reports 22(11): 63, Sept 2020.

Watach AJ, Xanthopoulos MS, Afolabi-Brown O, Saconi B, Sawyer AM. : Positive Airway Pressure Therapy in Pediatric Obstructive Sleep Apnea: A Scoping Review. Sleep Medicine Reviews. 51: 101273, June 2020.

Khaytin I, Tapia IE, Xanthopoulos M, Kim JY, Marcus CL, Beck SE. : AutoCPAP for the treatment of obstructive sleep apnea in children. Journal of Clinical Sleep Medicine 16(6): 871-878, June 2020.

Ishizuka M, Xanthopoulos MS, Tapia IE Stefanovski D, Beck SE, Afolabi-Brown O.: Trajectory of Positive Airway Pressure Initiated for Children with OSA While Inpatient. American Journal of Respiratory and Critical Care Medicine 201: A1160, 2020.

Watach A, Xanthopoulos MS, Afolabie-Brown O, Saconi B, Sawyer A: Adherence and Self-Management in Pediatric Populations. Sleep Disorders. A Modi & K Driscoll (eds.). Elsevier, Page: 379-408, 2020.

Beck SE, Moore M, Tapia I, Matthews E, Smith J, Brown C, DiSalvio W, Ewig J, Cielo CM, Afolabi-Brown O, Xanthopoulos MS.: PAP adherence, follow-up, and quality improvement in a pediatric sleep center. American Journal of Respiratory and Critical Care Medicine 201: A1155, 2020.

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Last updated: 02/22/2021
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