Henry R Kranzler
Karl E. Rickels Professor of Psychiatry
Co-Associate Director of Research, VISN 4 Mental Illness Research, Education, and Clinical Center (VAMC)
Director, Center for Studies of Addiction (PSOM)
Department: Psychiatry
Contact information
Treatment Research Center
3535 Market Street, Suite 500
Philadelphia, PA 19104-6178
3535 Market Street, Suite 500
Philadelphia, PA 19104-6178
Office: 215-746-1943
Email:
kranzler@mail.med.upenn.edu
kranzler@mail.med.upenn.edu
Publications
Education:
B.A. (Anthropology )
Monmouth University, 1976.
M.A. (Anthropology)
Rutgers University, 1980.
MD
UMDNJ - Robert Wood Johnson Medical School, 1982.
B.A. (Anthropology )
Monmouth University, 1976.
M.A. (Anthropology)
Rutgers University, 1980.
MD
UMDNJ - Robert Wood Johnson Medical School, 1982.
Post-Graduate Training
Psychiatry, University of Connecticut School of Medicine, 1982-1986.
Alcohol Studies, University of Connecticut School of Medicine, 1984-1987.
Permanent linkPsychiatry, University of Connecticut School of Medicine, 1982-1986.
Alcohol Studies, University of Connecticut School of Medicine, 1984-1987.
Selected Publications
Low A, Stiltner B, Nunez YZ, Adhikari K, Deak JD, Pietrzak RH, Kranzler HR, Gelernter J, Polimanti R.: Association patterns of antisocial personality disorder across substance use disorders. Transl Psychiatry 14: 346, Aug 2024.Reiner BC, Chehimi SN, Merkel R, Toikumo S, Berrettini WH, Kranzler HR, Sanchez-Roige S, Kember RL, Schmidt HD, Crist RC.: A single-nucleus transcriptomic atlas of medium spiny neurons in the rat nucleus accumbens. Sci Rep 14: 18258, Aug 2024.
Gupta P, Galimberti M, Liu Y, Beck S, Wingo A, Wingo T, Adhikari K, Kranzler HR; VA Million Veteran Program; Stein MB, Gelernter J, Levey DF.: A genome-wide investigation into the underlying genetic architecture of personality traits and overlap with psychopathology. Nat Hum Behav Aug 2024.
Malone SG, Davis CN, Piserchia Z, Setzer MR, Toikumo S, Zhou H, Winterlind EL, Gelernter J, Justice A, Leggio L, Rentsch CT, Kranzler HR, Gray JC.: Alcohol use disorder and body mass index show genetic pleiotropy and shared neural associations. medRxiv May 2024.
Khan Y, Davis CN, Jinwala Z, Feuer KL, Toikumo S, Hartwell EE, Sanchez-Roige S, Peterson RE, Hatoum AS, Kranzler HR, Kember RL.: Combining Transdiagnostic and Disorder-Level GWAS Enhances Precision of Psychiatric Genetic Risk Profiles in a Multi-Ancestry Sample. medRxiv May 2024.
Davis CN, Jinwala Z, Hatoum AS, Toikumo S, Agrawal A, Rentsch CT, Edenberg HJ, Baurley JW, Hartwell EE, Crist RC, Gray JC, Justice AC, Gelernter J, Kember RL, Kranzler HR.: Candidate Genes from an FDA-Approved Algorithm Fail to Predict Opioid Use Disorder Risk in Over 450,000 Veterans. medRxiv May 2024.
Davis C, Khan Y, Toikumo S, Jinwala Z, Boomsma D, Levey D, Gelernter J, Kember R, Kranzler H.: A Multivariate Genome-Wide Association Study Reveals Neural Correlates and Common Biological Mechanisms of Psychopathology Spectra. Res Sq Apr 2024.
Hartwell EE, Jinwala Z, Milone J, Ramirez S, Gelernter J, Kranzler HR, Kember RL.: Application of polygenic scores to a deeply phenotyped sample enriched for substance use disorders reveals extensive pleiotropy with psychiatric and medical traits. medRxiv Jan 2024.
Toikumo S, Vickers-Smith R, Jinwala Z, Xu H, Saini D, Hartwell EE, Pavicic M, Sullivan KA, Xu K, Jacobson DA, Gelernter J, Rentsch CT; Million Veteran Program; Stahl E, Cheatle M, Zhou H, Waxman SG, Justice AC, Kember RL, Kranzler HR.: A multi-ancestry genetic study of pain intensity in 598,339 veterans. Nat Med 2024.
Hartwell EE, Jinwala Z, Milone J, Ramirez S, Gelernter J, Kranzler HR, Kember RL.: Application of polygenic scores to a deeply phenotyped sample enriched for substance use disorders reveals extensive pleiotropy with psychiatric and somatic traits. Neuropsychopharmacology 2024.