faculty photo

Henry R Kranzler

Benjamin Rush Professor in Psychiatry
Co-Associate Director of Research, VISN 4 Mental Illness Research, Education, and Clinical Center (VAMC)
Director, Center for Studies of Addiction (PSOM)
Department: Psychiatry

Contact information
Treatment Research Center
3535 Market Street, Suite 500
Philadelphia, PA 19104-6178
Office: 215-746-1943
Education:
B.A. (Anthropology )
Monmouth University, 1976.
M.A. (Anthropology)
Rutgers University, 1980.
MD
UMDNJ - Robert Wood Johnson Medical School, 1982.
Post-Graduate Training
Psychiatry, University of Connecticut School of Medicine, 1982-1986.
Alcohol Studies, University of Connecticut School of Medicine, 1984-1987.
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Selected Publications

Dao C, Zhou H, Small A, Gordon KS, Li B, Kember RL, Ye Y, Gelernter J, Xu K, Kranzler HR,* Zhao H,* Justice AC.* *Co-senior authors: The impact of removing former drinkers from genome-wide association studies of AUDIT-C. Addiction 116(11): 3044-3054, Nov 2021.

Quijano Cardé NA, Perez EE, Kranzler HR, De Biasi M: Antagonism of GluK1-containing kainate receptors reduces ethanol consumption by modulating ethanol reward and withdrawal. Neuropharmacology 199: 108783, Nov 2021.

Hartwell E, Merikangas A, Verma S, Ritchie M, Kranzler HR,* Kember RL.* *Co-senior authors: Genetic liability for substance use associated with medical comorbidities in electronic health records of African- and European-ancestry individuals. Addiction Biology Page: e13099, Oct 2021.

Karlsson Linnér R, Mallard TT, Barr PB, Sanchez-Roige S, Madole JW, Driver MN, Poore HE, de Vlaming R, Grotzinger AD, Tielbeek JJ, Johnson EC, Liu M, Rosenthal SB, Ideker T, Zhou H, Kember RL, Pasman JA, Verweij KJH, Liu DJ, Vrieze S; COGA Collaborators, Kranzler HR, Gelernter J, Harris KM, Tucker-Drob EM, Waldman ID, Palmer AA, Harden KP, Koellinger PD, Dick DM: Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction. Nature Neuroscience 24(10): 1367-1376, Oct 2021.

Crist RC, Vickers-Smith R, Kember RL, Rentsch CT, Xu H, Edelman EJ, Hartwell EE, Kampman KM, Kranzler HR: Analysis of genetic and clinical factors associated with buprenorphine response. Drug and Alcohol Dependence 227: 109013, Oct 2021.

Roos CR, Bold KW, Witkiewitz K, Leeman RF, DeMartini KS, Fucito LM, Corbin WR, Mann K, Kranzler HR, O’Malley SS: Reward drinking and naltrexone treatment response among young adult heavy drinkers. Addiction 116(9): 2360-2371, Sep 2021.

Ma Y-J, Wang YY, Liu MQ, Fang T, Wei Z-R, Chen S-B, Tan H-Y, Nunez Y, Zhang X-J, Hao W, Kranzler HR, Gelernter J, Liu T-Q, Yang B-Z: Reliability and validity of DSM-IV and DSM-5 methamphetamine use disorder diagnoses using the Chinese version of the Semi-Structured Assessment for Drug Dependence and Alcoholism (SSADDA). Drug and Alcohol Dependence, in press. 229(Pt B): 109047, Sep 2021.

Kranzler HR, Hartwell EE, Feinn R, Pond T, Witkiewitz K, Gelernter J, Crist RC: Combined analysis of the moderating effect of a GRIK1 polymorphism on the effects of topiramate for treating alcohol use disorder. Drug and Alcohol Dependence 225: 108762, Aug 2021.

Hartwell EE, Feinn R, Witkiewitz K, Pond T, Kranzler HR: World Health Organization Risk Drinking Levels as a treatment outcome measure in topiramate trials. Alcoholism: Clinical and Experimental Research 45(8): 1664-1671, Aug 2021.

Kranzler HR, Morris PE, Pond T, Crist RC, Kampman KM, Hartwell EE, Lynch KG: Prospective randomized pharmacogenetic study of topiramate for treating alcohol use disorder. Neuropsychopharmacology 46(8): 1407-1413, Jul 2021.

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Last updated: 11/12/2021
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