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Reagan R. Wetherill
4eAdjunct Associate Professor of Psychiatry
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Department: Psychiatry
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Contact information
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Center for Studies of Addiction
40 3535 Market Street, Suite 500
Philadelphia, PA 19104
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40 3535 Market Street, Suite 500
Philadelphia, PA 19104
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Office: (215) 746-3953
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Publications
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Links
ba Search PubMed for articles
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ba Search PubMed for articles
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Education:
21 9 B.S. 19 (Neuroscience) c
2e Vanderbilt University, 2002.
21 9 M.A. 20 (Clinical Psychology) c
36 University of Texas at Austin, 2006.
21 a Ph.D. 20 (Clinical Psychology) c
36 University of Texas at Austin, 2010.
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21 9 B.S. 19 (Neuroscience) c
2e Vanderbilt University, 2002.
21 9 M.A. 20 (Clinical Psychology) c
36 University of Texas at Austin, 2006.
21 a Ph.D. 20 (Clinical Psychology) c
36 University of Texas at Austin, 2010.
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Post-Graduate Training
24 b4 Clinical Psychology Intern, Veterans Affairs San Diego Healthcare System/University of California, San Diego School of Medicine, San Diego, California, 2009-2010.
24 81 Postdoctoral Fellow, Department of Psychiatry, University of California, San Diego School of Medicine, San Diego, California 1b , 2010-2011.
24 91 Postdoctoral Researcher, Department of Psychiatry, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania 1b , 2012-2013.
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Permanent link24 b4 Clinical Psychology Intern, Veterans Affairs San Diego Healthcare System/University of California, San Diego School of Medicine, San Diego, California, 2009-2010.
24 81 Postdoctoral Fellow, Department of Psychiatry, University of California, San Diego School of Medicine, San Diego, California 1b , 2010-2011.
24 91 Postdoctoral Researcher, Department of Psychiatry, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania 1b , 2012-2013.
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Description of Clinical Expertise
7e Dr. Gehrman is a licensed clinical psychologist who specializes in Neuropsychology and Alcohol/Drug Treatment.71
Description of Research Expertise
3f3 Guided by neuroscience and clinical neuroimaging techniques, Dr. Wetherill's translational research program is focused on improving treatment outcomes for addictive disorders by (1) identifying individual differences in brain and behavioral vulnerabilities for developing and maintaining addictive disorders, (2) evaluating brain changes following chronic substance use, and (3) identifying mechanisms of treatment effect. Her research has varied across different populations (adolescents, adults, youth at risk, individuals with tobacco use disorder, alcohol use disorder, cannabis use disorder, opioid use disorder, HIV) and study design/approach (longitudinal cohort, randomized clinical trial, human laboratory, molecular imaging, and neuroimaging). Dr. Wetherill is an internationally-recognized expert in alcohol-induced memory impairments, specifically alcohol-induced blackouts, and serves as an expert consultant/witness for the Penn Title IX office and in military and civilian courts.e 29
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170 Ashare, R.L., Turay, E., Worster, B., Wetherill, R.R., Bidwell, L.C., Doucette, A., Meghani, S.H.: Social determinants of health associated with how cannabis is obtained and used in patients with cancer receiving care at a cancer treatment center in Pennsylvania. Cannabis 6(2): 1-12, July 2023.
111 Wetherill, R.R., Dubroff, J.G.: Reply: Molecular Imaging of Pulmonary Inflammation: Claiming That Vaping Is More Harmful Than Smoking Is Unsupported. Journal of Nuclear Medicine 64(6): 995, June 2023.
186 Wetherill, R.R., Doot, R.K., Young, A.J., Lee, H., Schubert, E.K., Wiers, C.E., Leone, F.T., Mach, R.H., Kranzler, H.R., Dubroff, J.G.: Molecular imaging of pulmonary inflammation in electronic and combustible cigarette users: a pilot study. Journal of Nuclear Medicine Jan 2023 Notes: doi: 10.2967/jnumed.122.264529.
169 Franklin, T.R., Spilka, N.H., Keyser, H., Maron, M., Jagannathan, K., Wetherill, R.R.: Impact of the natural hormonal milieu on ventral striatal responses to appetitive cigarette smoking cues: a prospective longitudinal study. Drug and Alcohol Dependence Reports 5: 100119, December 2022.
17d Regier, P.S., Gawrysiak, M.J., Jagannathan, K., Childress, A.R., Franklin, T.R., Wetherill, R.R.: Trauma exposure among cannabis use disorder individuals was associated with a craving-correlated non-habituating amygdala response to aversive cues. Drug and Alcohol Dependence Reports 5: 100098, December 2022.
8e Doot, R.K., Young, A.J., Nasrallah, I.M., Wetherill, R.R., Siderowf, A., Mach, R.H., Dubroff, J.G. a2 : [18F]NOS PET brain imaging suggests elevated neuroinflammation in idiopathic parkinson’s disease. Cells 11(19): 3081, Sep 2022.
148 Daviet, R., Aydogan, G., Jagannathan, K., Spilka, N., Koellinger, P.D., Kranzler, H.R., Nave, G., Wetherill, R.R.: Associations between alcohol consumption and gray and white matter volumes in the UK Biobank. Nature Communications 13(1): 1175, March 2022.
3b2 Ekhtiari, H., Zare-Bidoky, M., Sangchooli, A., Janes, A., Kaufman, M.J., Oliver, J., Prisciandaro, J.J., Wüstenberg, T., Anton, R.A., Bach, P., Baldacchino, A., Beck, A., Bjorks, J., Brewer, J., Childress, A.C., Claus, E., Courtney, K., Ebrahimi, M., Filbey, F., Ghahremani, D., Azbari, P.G., Goldstein, R., Goudrian, A., Grodin, E., Hamilton, P., Hanlon, C.A., Hasani Abharian, P., Heinz, A., Joseph, J.E., Kiefer, F., Khojasteh-Zonoozi, A., Kober, H., Kuplicki, R., Li, Q., London, E.D., McClernon, J., Noori, H., Owens, M., Paulus, M., Perini, I., Potenza, M., Potvin, S., Ray, L., Schacht, J., Seo, D., Sinha, R., Smolka, M.N., Spanagel, R., Steele, V., Stein, E., Loeber, S.L., Tapert, S., Verdejo-Garcia, A., Vollstaedt-Klein, A., Wetherill, R., Wilson, S., Witkiewitz, K., Yuan, K., Zhang, X., Zilverstand, A.: A methodological checklist for fMRI drug cue reactivity studies: development 5a and expert consensus. Nature Protocols 17(3): 567-595, March 2022.
146 Ely, A.V., Keyser, H., Spilka, N., Franklin, T.R., Wetherill, R.R., Audrain-McGovern, J.: An exploration of associations between smoking motives and behavior as a function of body mass index. Drug and Alcohol Dependence Reports 1: 100008, November 2021.
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Selected Publications
166 Hartwell, E.E., Schwandt, M., Nunez, Y.Z., Wetherill, R.R., Kember, R.L., Wiers, C.E., Gelernter, J., Kranzler, H.R.: Identifying neurofunctional domains across substance use disorders. American Journal of Drug and Alcohol Abuse. American Journal of Drug and Alcohol Abuse, July 2024.170 Ashare, R.L., Turay, E., Worster, B., Wetherill, R.R., Bidwell, L.C., Doucette, A., Meghani, S.H.: Social determinants of health associated with how cannabis is obtained and used in patients with cancer receiving care at a cancer treatment center in Pennsylvania. Cannabis 6(2): 1-12, July 2023.
111 Wetherill, R.R., Dubroff, J.G.: Reply: Molecular Imaging of Pulmonary Inflammation: Claiming That Vaping Is More Harmful Than Smoking Is Unsupported. Journal of Nuclear Medicine 64(6): 995, June 2023.
186 Wetherill, R.R., Doot, R.K., Young, A.J., Lee, H., Schubert, E.K., Wiers, C.E., Leone, F.T., Mach, R.H., Kranzler, H.R., Dubroff, J.G.: Molecular imaging of pulmonary inflammation in electronic and combustible cigarette users: a pilot study. Journal of Nuclear Medicine Jan 2023 Notes: doi: 10.2967/jnumed.122.264529.
169 Franklin, T.R., Spilka, N.H., Keyser, H., Maron, M., Jagannathan, K., Wetherill, R.R.: Impact of the natural hormonal milieu on ventral striatal responses to appetitive cigarette smoking cues: a prospective longitudinal study. Drug and Alcohol Dependence Reports 5: 100119, December 2022.
17d Regier, P.S., Gawrysiak, M.J., Jagannathan, K., Childress, A.R., Franklin, T.R., Wetherill, R.R.: Trauma exposure among cannabis use disorder individuals was associated with a craving-correlated non-habituating amygdala response to aversive cues. Drug and Alcohol Dependence Reports 5: 100098, December 2022.
8e Doot, R.K., Young, A.J., Nasrallah, I.M., Wetherill, R.R., Siderowf, A., Mach, R.H., Dubroff, J.G. a2 : [18F]NOS PET brain imaging suggests elevated neuroinflammation in idiopathic parkinson’s disease. Cells 11(19): 3081, Sep 2022.
148 Daviet, R., Aydogan, G., Jagannathan, K., Spilka, N., Koellinger, P.D., Kranzler, H.R., Nave, G., Wetherill, R.R.: Associations between alcohol consumption and gray and white matter volumes in the UK Biobank. Nature Communications 13(1): 1175, March 2022.
3b2 Ekhtiari, H., Zare-Bidoky, M., Sangchooli, A., Janes, A., Kaufman, M.J., Oliver, J., Prisciandaro, J.J., Wüstenberg, T., Anton, R.A., Bach, P., Baldacchino, A., Beck, A., Bjorks, J., Brewer, J., Childress, A.C., Claus, E., Courtney, K., Ebrahimi, M., Filbey, F., Ghahremani, D., Azbari, P.G., Goldstein, R., Goudrian, A., Grodin, E., Hamilton, P., Hanlon, C.A., Hasani Abharian, P., Heinz, A., Joseph, J.E., Kiefer, F., Khojasteh-Zonoozi, A., Kober, H., Kuplicki, R., Li, Q., London, E.D., McClernon, J., Noori, H., Owens, M., Paulus, M., Perini, I., Potenza, M., Potvin, S., Ray, L., Schacht, J., Seo, D., Sinha, R., Smolka, M.N., Spanagel, R., Steele, V., Stein, E., Loeber, S.L., Tapert, S., Verdejo-Garcia, A., Vollstaedt-Klein, A., Wetherill, R., Wilson, S., Witkiewitz, K., Yuan, K., Zhang, X., Zilverstand, A.: A methodological checklist for fMRI drug cue reactivity studies: development 5a and expert consensus. Nature Protocols 17(3): 567-595, March 2022.
146 Ely, A.V., Keyser, H., Spilka, N., Franklin, T.R., Wetherill, R.R., Audrain-McGovern, J.: An exploration of associations between smoking motives and behavior as a function of body mass index. Drug and Alcohol Dependence Reports 1: 100008, November 2021.
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