Benjamin C. Reiner
Research Assistant Professor of Psychiatry
Department: Psychiatry
Contact information
TRL Building, 125 S. 31st St.
Department of Psychiatry
Perelman School of Medicine
University of Pennsylvania
Philadelphia, PA 19104
Department of Psychiatry
Perelman School of Medicine
University of Pennsylvania
Philadelphia, PA 19104
Office: 2155730278
Publications
Education:
BS (Biology, minor Chemistry)
University of Nebraska at Omaha, 2007.
PhD (Pharmacology and Experimental Neuroscience)
University of Nebraska Medical Center, 2015.
BS (Biology, minor Chemistry)
University of Nebraska at Omaha, 2007.
PhD (Pharmacology and Experimental Neuroscience)
University of Nebraska Medical Center, 2015.
Post-Graduate Training
Postdoctoral Fellowship, Neurogenetics, Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 2016-2020.
Research Associate, Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 2020-2022.
Permanent linkPostdoctoral Fellowship, Neurogenetics, Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 2016-2020.
Research Associate, Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 2020-2022.
Description of Research Expertise
My lab focuses on using behavioral, pharmacological, and intersectional genetic approaches with neural multiomics and downstream bioinformatics in preclinical animal models and postmortem human tissue in psychiatric disease, substance use disorders, and diseases of feeding and energy balance.Selected Publications
Guo X, Keenan BT, Reiner BC, Lian J, Pack A.: Single-nucleus RNA-seq identifies one galanin neuronal subtype in mouse preoptic hypothalamus activated during recovery from sleep deprivation. Cell Reports 2024.Crist RC, Chehimi SN***, Montague MJ, Snyder-Mackler N, Bohlen MO, Chiou KL, Zintel TM, Platt ML, Silvestri G, Hayes MR, Kolson DL, Reiner BC: SIV infection induces alterations in gene expression and loss of interneurons in Rhesus Macaque frontal cortex during early systemic infection. Translational Psychiatry 2024.
Weller AE, Ferraro TN, Doyle GA, Reiner BC, Berrettini WH, Crist RC: Analysis of single-cell transcriptome data from a mouse model implicates protein synthesis dysfunction in schizophrenia. Genes & Genomics 2024.
Reiner BC, Chehimi SN, Merkel R, Toikumo S, Berrettini WH, Kranzler HR, Sanchez-Roige S, Kember RL, Schmidt HD, Crist RC: A single-nucleus transcriptomic atlas of medium spiny neurons in the rat nucleus accumbens. Scientific Reports 2024.
Corley C, Craig A, Sadek S, Marusich JA, Chehimi SN, White AM, Holdiness LJ, Reiner BC, Gipson CD: Enhancing translation: A need to leverage complex preclinical models of addictive drugs to accelerate substance use treatment options. Pharmacology Biochemistry and Behavior 2024.
SN Chehimi, RC Crist, BC Reiner: Unraveling Psychiatric Disorders through Neural Single-Cell Transcriptomics Approaches. Genes 14(3), March 2023.
T Borner, BC Reiner, RC Crist, CD Furst, SA Doebley, JG Halas, M Ai, RJ Samms, BC De Jonghe, MR Hayes: GIP receptor agonism blocks chemotherapy-induced nausea and vomiting. Molecular Metabolism 2023.
MJ Sanchez-Navarro, T Borner, BC Reiner, RC Crist, WK Samson, GLC Yosten, L Stein, MR Hayes: GPR-160 Receptor Signaling in the Dorsal Vagal Complex of Male Rats Modulates Meal Microstructure and CART-Mediated Hypophagia. Nutrients 2023.
W Ma, MC Oliveira-Nunes, K Xu, A Kossenkov, BC Reiner, RC Crist, J Hayden, Q Chen: Type I interferon response in astrocytes promotes brain metastasis by enhancing monocytic myeloid cell recruitment. Nature Communications 2023.
Y Zhang, JB Nathan, A Moreno, R Merkel, MW Kahng, MR Hayes, BC Reiner, RC Crist, HD Schmidt: Calcitonin receptor signaling in nucleus accumbens D1R-and D2R-expressing medium spiny neurons bidirectionally alters opioid taking in male rats. Neuropsychopharmacology 2023.