Cesar de la Fuente
Presidential Associate Professor
Department: Psychiatry
Graduate Group Affiliations
Contact information
Robert Wood Johnson Pavilion / 3610 Hamilton Walk
Lab: Room 302C
Office: Room 303C
Philadelphia, PA 19104
Lab: Room 302C
Office: Room 303C
Philadelphia, PA 19104
Office: 2157466083
Publications
Education:
B.Sc. (Biotechnology)
University of Leon, 2009.
Ph.D. (Microbiology & Immunology)
University of British Columbia, 2014.
B.Sc. (Biotechnology)
University of Leon, 2009.
Ph.D. (Microbiology & Immunology)
University of British Columbia, 2014.
Post-Graduate Training
Postdoctoral Fellow, Microbiology & Immunology, University of British Columbia, 2014-2015.
Postdoctoral Fellow, Synthetic Biology, Biological Engineering, Electrical Engineering and Computer Science, MIT, 2015-2017.
Postdoctoral Associate, Synthetic Biology, Biological Engineering, Electrical Engineering and Computer Science, MIT, 2015-2019.
Permanent linkPostdoctoral Fellow, Microbiology & Immunology, University of British Columbia, 2014-2015.
Postdoctoral Fellow, Synthetic Biology, Biological Engineering, Electrical Engineering and Computer Science, MIT, 2015-2017.
Postdoctoral Associate, Synthetic Biology, Biological Engineering, Electrical Engineering and Computer Science, MIT, 2015-2019.
Selected Publications
William F. Porto, Luz Irazazabal, Eliane S. F. Alves, Suzana M. Ribeiro, Carolina O. Matos, Állan S. Pires, Isabel C. M. Fensterseifer, Vivian J. Miranda, Evan F. Haney, Vincent Humblot, Robert E. W. Hancock, Luciano M. Liao, Ali Ladram, Timothy K. Lu, César de la Fuente-Núñez#, and Octavio L. Franco#: In silico optimization of a guava antimicrobial peptide enables combinatorial exploration for peptide design. Nature Communications 9(1): 1490, April 2018 Notes: doi: 10.1038/s41467-018-03746-3. # indicates corresponding authorship.Marcelo D. T. Torres, Cibele N. Pedron, Yasutomi Higashikuni, Robin M. Kramer, Marlon H. Cardoso, Karen G. N. Oshiro, Octávio L. Franco, Pedro I. Silva Junior, Fernanda D. Silva, Vani X. Oliveira Junior#, Timothy K. Lu#, Cesar de la Fuente-Nunez#: Structure-function-guided exploration of the antimicrobial peptide polybia-CP identifies activity determinants and generates synthetic therapeutic candidates Nature Communications Biology 1(221), December 2018 Notes: doi: 10.1038/s42003-018-0224-2. # indicates corresponding authorship.
Katia Pane, Valeria Cafaro, Angela Avitabile, Marcelo der Torossian Torres, Adriana Vollaro, Eliana De Gregorio, Maria Rosaria Catania, Antimo Di Maro, Andrea Bosso, Giovanni Gallo, Anna Zanfardino, Mario Varcamonti, Elio Pizzo, Alberto Di Donato, Timothy K. Lu, Cesar de la Fuente-Núñez#, Eugenio Notomista#: Identification of novel cryptic multifunctional antimicrobial peptides from the human stomach enabled by a computational-experimental platform. ACS Synthetic Biology 7(9): 2105-2115, September 2018 Notes: doi: 10.1021/acssynbio.8b00084. Epub 2018 August 20. # indicates corresponding authorship.
Marcelo D. T. Torres, Shanmugapriya Sothiselvam, Timothy K. Lu, Cesar de la Fuente-Nunez#: Peptide Design Principles for Antimicrobial Applications. Journal of Molecular Biology 431(18): 3547-3567, August 2019 Notes: pii: S0022-2836(18)31289-0. doi: 10.1016/j.jmb.2018.12.015. # indicates corresponding authorship.
Cesar de la Fuente-Núñez#, Beatriz Torres Meneguetti, Octávio Luiz Franco, Timothy K. Lu#: Neuromicrobiology: how microbes influence the brain. ACS Chemical Neuroscience 9(2): 141-150, February 2018 Notes: doi: 10.1021/acschemneuro.7b00373. # indicates corresponding authorship.
Marcelo Der Torossian Torres, Cesar de la Fuente-Nunez: Toward computer-made artificial antibiotics. Current Opinion in Microbiology 51: 30-38, October 2019 Notes: doi: 10.1016/j.mib.2019.03.004.
Marcelo Der Torossian Torres, and Cesar de la Fuente-Nunez: Reprogramming biological peptides to combat infectious diseases. Chemical Communications (Cambridge, England) 55(100): 15020-15032, November 2019 Notes: doi: 10.1039/C9CC07898C.
María Eugenia Inda, Esther Broset, Timothy K. Lu, and Cesar de la Fuente-Nunez: Emerging Frontiers in Microbiome Engineering. Trends in Immunology 40(10): 952-973, October 2019 Notes: doi: 10.1016/j.it.2019.08.007.
Kevin Yehl, Sébastien Lemire, Andrew C. Yang, Hiroki Ando, Mark Mimee, Marcelo Der Torossian Torres, Cesar de la Fuente-Nunez, and Timothy K. Lu: Engineering Phage Host-Range and Suppressing Bacterial Resistance through Phage Tail Fiber Mutagenesis. Cell 179(2): 459-469.e9, October 2019 Notes: doi: 10.1016/j.cell.2019.09.015.