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Marcelo Der Torossian Torres
4fResearch Assistant Professor of Psychiatry
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Department: Psychiatry
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Contact information
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3610 Hamilton Walk, Room 302C
Philadelphia, PA 19104
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Philadelphia, PA 19104
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Email:
marcelot@upenn.edu
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marcelot@upenn.edu
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Publications
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Education:
21 a B.Sc. 23 (Science and technology) c
3b Federal University of ABC - Brazil, 2010.
21 a B.Sc. 16 (Chemistry) c
3b Federal University of ABC - Brazil, 2011.
21 a M.Sc. 2d (Science and Technology/Chemistry) c
3b Federal University of ABC - Brazil, 2013.
21 a Ph.D. 2d (Science and Technology/Chemistry) c
3b Federal University of ABC - Brazil, 2018.
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21 a B.Sc. 23 (Science and technology) c
3b Federal University of ABC - Brazil, 2010.
21 a B.Sc. 16 (Chemistry) c
3b Federal University of ABC - Brazil, 2011.
21 a M.Sc. 2d (Science and Technology/Chemistry) c
3b Federal University of ABC - Brazil, 2013.
21 a Ph.D. 2d (Science and Technology/Chemistry) c
3b Federal University of ABC - Brazil, 2018.
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Post-Graduate Training
24 6d Undergraduate fellowship, Brazilian National Council for Scientific and Technological Development (CNPq) 1b , 2008-2011.
24 4f Masters fellowship, São Paulo Research Foundation (FAPESP): #2011/15083-3 1b , 2011-2013.
24 69 Doctoral fellowship, São Paulo Research Foundation (FAPESP): #2014/04507-5, 2014-2018.
24 98 Visiting doctoral fellowship, São Paulo Research Foundation (FAPESP): One year fellowship at Massachusetts Institute of Technology (#2016/24413-0) 1b , 2017-2018.
24 94 Visiting Post-doctoral Researcher, Instituto de Química Orgánica General, IQOG/CSIC, Spain (MIT-Spain Joint Program), 2018-2018.
24 4d Postdoctoral Fellow, University of Pennsylvania, 2019-2024.
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Permanent link24 6d Undergraduate fellowship, Brazilian National Council for Scientific and Technological Development (CNPq) 1b , 2008-2011.
24 4f Masters fellowship, São Paulo Research Foundation (FAPESP): #2011/15083-3 1b , 2011-2013.
24 69 Doctoral fellowship, São Paulo Research Foundation (FAPESP): #2014/04507-5, 2014-2018.
24 98 Visiting doctoral fellowship, São Paulo Research Foundation (FAPESP): One year fellowship at Massachusetts Institute of Technology (#2016/24413-0) 1b , 2017-2018.
24 94 Visiting Post-doctoral Researcher, Instituto de Química Orgánica General, IQOG/CSIC, Spain (MIT-Spain Joint Program), 2018-2018.
24 4d Postdoctoral Fellow, University of Pennsylvania, 2019-2024.
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125 Araujo, WR; Lukas, H; Torres, MDT; Gao, W; de la Fuente-Nunez, C. : Low-cost Biosensors Technologies for Rapid Detection of COVID-19 and Future Pandemics. ACS Nano 18: 1757-1777, 2024 Notes: DOI: 10.1021/acsnano.3c01629.
130 Reffuveille, F; Dghoughi, T; Colin, M; Torres, MDT; de la Fuente-Nunez, C. : Antibiofilm approaches as a new paradigm for treating infections. Progress in Biomedical Engineering 6: 023001, 2024 Notes: DOI: 10.1088/2516-1091/ad1cd6.
180 Silva, AF; Torres, MDT; Silva, LS; Alves, FL; Pinheiro, AAS; Miranda, A; de la Fuente-Nunez, C; Oliveira, VX Jr.: Synthetic angiotensin II derivatives with anti-infective efficacy in a preclinical murine model of severe cerebral malaria. Scientific Reports 14: 4682, 2024 Notes: DOI: 10.1038/s41598-024-51267-5.
139 Torres, MDT; Brooks, E; Cesaro, A; Sberro, H; Nicolaou, C; Bhatt, AS; de la Fuente-Nunez, C. : Human gut metagenomic mining reveals an untapped source of peptide antibiotics. Cell 187: 5453-5467, 2024 Notes: DOI: 10.1016/j.cell.2024.07.027.
1ae Santos-Junior, CD; Torres, MDT; Duas, Y; del Rio, AR; Schmidt, TSB; Chong, H; Fullam, A; Kuhn, M; Zhu, C; Houseman, A; Somborski, J; Vines, A; Zhao, XM; Bork, P; Huerta-Cepas, J; de la Fuente-Nunez, C, Coelho, LP.: Computational exploration of the global microbiome for antibiotic discovery. Cell 187: 3761-3778, 2024 Notes: DOI: 10.1016/j.cell.2024.05.013.
1e3 Deb, R; Torres, MDT; Boudny, M; Koberska, M; Cappiello, F; Petrik, M; Bendova, KD; Drabinova, M; Hanackova, A; Jeannot, K; Popper, M; Mangoni, ML; Novotna, GB; Mraz, M, de la Fuente-Nunez, C; Vacha, R. : Computational design of barrel-stave pore-forming peptides with potent antimicrobial and anticancer activities. Journal of Medicinal Chemistry 67: 14040-14061, 2024 Notes: DOI: 10.1021/acs.jmedchem.4c00912.
117 Wan, F; Torres, MDT; Peng, J, de la Fuente-Nunez, C. : Molecular de-extinction of antibiotics enabled by deep learning. Nature Biomedical Engineering 8: 854-871, 2024 Notes: DOI: 10.1038/s41551-024-01201-x.
16c De los Santos, L; Sheiber, J; DeBarro, C; Keener, J; Torres, MDT; de la Fuente-Nunez, C; Brodbelt, JS; Fleeman, RM.: Polyproline peptide targets Klebsiella pneumoniae polysaccharides to collapse biofilms. Cell Reports Physical Sciences 5: 101869, 2024 Notes: DOI: 10.1016/j.xcrp.2024.101869.
174 Lima, LF; Ferreira, AL; Awasthi, S; Torres, MDT; Friedman, HM; Cohen, G; Araujo, WR; de la Fuente-Nunez, C.: Rapid and accurate detection of Herpes Simplex Virus type 2 using a low-cost electrochemical biosensor. Cell Reports Physical Sciences 4: 101513, 2023 Notes: DOI: 10.1016/j.xcrp.2023.101513.
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Selected Publications
140 Torres, MDT; Cesaro, A; de la Fuente-Nunez, C. : Peptides from non-immune proteins target infections through antimicrobial and immunomodulatory properties. Trends in Biotechnology 43(1): 184-205, Jan 2025 Notes: DOI: 10.1016/j.tibtech.2024.09.008.125 Araujo, WR; Lukas, H; Torres, MDT; Gao, W; de la Fuente-Nunez, C. : Low-cost Biosensors Technologies for Rapid Detection of COVID-19 and Future Pandemics. ACS Nano 18: 1757-1777, 2024 Notes: DOI: 10.1021/acsnano.3c01629.
130 Reffuveille, F; Dghoughi, T; Colin, M; Torres, MDT; de la Fuente-Nunez, C. : Antibiofilm approaches as a new paradigm for treating infections. Progress in Biomedical Engineering 6: 023001, 2024 Notes: DOI: 10.1088/2516-1091/ad1cd6.
180 Silva, AF; Torres, MDT; Silva, LS; Alves, FL; Pinheiro, AAS; Miranda, A; de la Fuente-Nunez, C; Oliveira, VX Jr.: Synthetic angiotensin II derivatives with anti-infective efficacy in a preclinical murine model of severe cerebral malaria. Scientific Reports 14: 4682, 2024 Notes: DOI: 10.1038/s41598-024-51267-5.
139 Torres, MDT; Brooks, E; Cesaro, A; Sberro, H; Nicolaou, C; Bhatt, AS; de la Fuente-Nunez, C. : Human gut metagenomic mining reveals an untapped source of peptide antibiotics. Cell 187: 5453-5467, 2024 Notes: DOI: 10.1016/j.cell.2024.07.027.
1ae Santos-Junior, CD; Torres, MDT; Duas, Y; del Rio, AR; Schmidt, TSB; Chong, H; Fullam, A; Kuhn, M; Zhu, C; Houseman, A; Somborski, J; Vines, A; Zhao, XM; Bork, P; Huerta-Cepas, J; de la Fuente-Nunez, C, Coelho, LP.: Computational exploration of the global microbiome for antibiotic discovery. Cell 187: 3761-3778, 2024 Notes: DOI: 10.1016/j.cell.2024.05.013.
1e3 Deb, R; Torres, MDT; Boudny, M; Koberska, M; Cappiello, F; Petrik, M; Bendova, KD; Drabinova, M; Hanackova, A; Jeannot, K; Popper, M; Mangoni, ML; Novotna, GB; Mraz, M, de la Fuente-Nunez, C; Vacha, R. : Computational design of barrel-stave pore-forming peptides with potent antimicrobial and anticancer activities. Journal of Medicinal Chemistry 67: 14040-14061, 2024 Notes: DOI: 10.1021/acs.jmedchem.4c00912.
117 Wan, F; Torres, MDT; Peng, J, de la Fuente-Nunez, C. : Molecular de-extinction of antibiotics enabled by deep learning. Nature Biomedical Engineering 8: 854-871, 2024 Notes: DOI: 10.1038/s41551-024-01201-x.
16c De los Santos, L; Sheiber, J; DeBarro, C; Keener, J; Torres, MDT; de la Fuente-Nunez, C; Brodbelt, JS; Fleeman, RM.: Polyproline peptide targets Klebsiella pneumoniae polysaccharides to collapse biofilms. Cell Reports Physical Sciences 5: 101869, 2024 Notes: DOI: 10.1016/j.xcrp.2024.101869.
174 Lima, LF; Ferreira, AL; Awasthi, S; Torres, MDT; Friedman, HM; Cohen, G; Araujo, WR; de la Fuente-Nunez, C.: Rapid and accurate detection of Herpes Simplex Virus type 2 using a low-cost electrochemical biosensor. Cell Reports Physical Sciences 4: 101513, 2023 Notes: DOI: 10.1016/j.xcrp.2023.101513.
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