Katherine Scangos
Associate Professor of Psychiatry at the Hospital of the University of Pennsylvania
Director, Brain Circuit Therapeutics Clinic, University of Pennsylvania
Member of Center for Brain Imaging and Stimulation, University of Pennsylvania
Member of Center for Neuromodulation of Depression and Stress, University of Pennsylvania
Member of Penn Brain Science, Translation, Innovation, and Modulation Center, University of Pennsylvania
Department: Psychiatry
Contact information
801 Spruce Street
Philadelphia, PA 19107
Philadelphia, PA 19107
Links
Researches Show Efficacy Of Personalized Brain Stimulation In Psychiatric Treatments, NPR, by Jon Hamilton, Jan 18, 2021
Brain Implant May Lift Most Severe Depression, BBC, by Michelle Roberts, Oct 4, 2021
A ‘Pacemaker for the Brain’: No Treatment Helped Her Depression — Until This, New York Times, by Pam Bullock, Oct 4 2021
A Better Way to Zap Our Brains, New York Times Magazine, by Kim Tingley, Feb 24, 2021
Researches Show Efficacy Of Personalized Brain Stimulation In Psychiatric Treatments, NPR, by Jon Hamilton, Jan 18, 2021
Brain Implant May Lift Most Severe Depression, BBC, by Michelle Roberts, Oct 4, 2021
A ‘Pacemaker for the Brain’: No Treatment Helped Her Depression — Until This, New York Times, by Pam Bullock, Oct 4 2021
A Better Way to Zap Our Brains, New York Times Magazine, by Kim Tingley, Feb 24, 2021
Education
B.A. (Biology)
Amherst College, 2002.
MD, Ph.D. (Neuroscience)
John Hopkins School of Medicine, 2012.
B.A. (Biology)
Amherst College, 2002.
MD, Ph.D. (Neuroscience)
John Hopkins School of Medicine, 2012.
Post-Graduate Training
Psychiatry Residency, University of California, Davis, 2013-2017.
Chief Residency, University of California, Davis, 2016-2017.
Interventional Psychiatry Fellowship, University of California, San Francisco, 2017-2018.
Permanent linkPsychiatry Residency, University of California, Davis, 2013-2017.
Chief Residency, University of California, Davis, 2016-2017.
Interventional Psychiatry Fellowship, University of California, San Francisco, 2017-2018.
Selected Publications
Farooqui J, Toennies J, Mintch LM, Nelson J, Yudkoff B, Cristancho M, Scangos K, Halpern CH, Robinson JT, Wexler A.: What matters in next-generation implanted neurotechnology design? Perspectives from individuals with treatment-refractory depression. J Neural Eng Aug 2026.Lauro PM, Palmer CF, Nambiar MM, Muller U, Qiu L, Halpern CH, Scangos KW.: Circuit-based neuromodulation for obsessive-compulsive disorder: a review of prior and emerging methods. Front Psychiatry 17: 1828620, Jul 2026.
Seilheimer RL, Qiu L, Rocchio G, Nho YH, Campos G, Horn A, Rolle CE, Buch VP, Ganguly TM, Cristancho M, Oathes DJ, Brown L, Pesaran B, Krystal AD, Chang EF, Lee MA, Miller KJ, Barbosa DAN, Williams NR, Halpern CH, Scangos KW.: Stereo-encephalography-guided multi-lead deep brain stimulation for treatment-refractory obsessive compulsive disorder - Study design and individualized surgical targeting approach. J Affect Disord 402: 121349, Jun 2026.
Fleeting CR, Moraud EM, Uğurbil K, Wang DD, Neumann WJ, Kühn AA, Voon V, Pikov V, Welter ML, Fox MD, Rolston JD, Malekmohammadi M, Pathak YJ, Himes LM, Greene D, Holt-Becker AS, Lázaro-Muñoz G, Charney AW, Merner AR, Figee M, Scangos KW, Denison T, Leyde K, Gunduz A, Bronte-Stewart HM, Beck JC, Vanegas-Arroyave N, Luciano MS, Brüggemann N, Foote KD, Okun MS, Wong JK.: Proceedings of the 13th annual deep brain stimulation think tank: the evolving landscape. Front Hum Neurosci 20: 1770451, Mar 2026.
Nho YH, Qiu L, Seilheimer RL, Campos G, Chang A, Wang Z, Magnotti JF, Beauchamp MS, Barbosa DAN, Horn A, Williams NR, Brown LA, Ganguly TM, Cristancho M, Pesaran B, Oathes DJ, Miller KJ, Scangos KW, Halpern CH.: Human orbitofrontal neural activity is linked to obsessive-compulsive behavioral dynamics. Cell 189: 739-747, Feb 2026.
Qiu L, Nho YH, Seilheimer RL, Kim MJ, Tufanoglu A, Williams NR, Wexler A, Oslin DW, Millet B, Scangos KW, Pesaran B, Evins AE, Richardson RM, Childress AR, Halpern CH.: Electrographic cue-reactivity co-localizes with accumbens deep brain stimulation in a case of opioid use disorder. Nat Commun 17: 1708, Jan 2026.
Howard SD, Qiu L, Hager N, Childress AR, Halpern CH, Scangos KW.: Emerging neuromodulation treatments for opioid and stimulant use disorders. Front Hum Neurosci. 19, Oct 2025.
Seilheimer RL, Qiu L, Rocchio G, Nho YH, Campos G, Horn A, Rolle CE, Buch VP, Ganguly TM, Cristancho M, Oathes DJ, Brown L, Pesaran B, Krystal AD, Chang EF, Lee ME, Miller KJ, Williams NR, Barbosa DAN, Scangos KW, Halpern CH.: Stereo-encephalography-guided multi-lead deep brain stimulation for treatment-refractory obsessive compulsive disorder - study design and individualized surgical targeting approach. medRxiv Jul 2025.
Liming Qiu, Young-Hoon Nho, Robert Seilheimer, Min Jae Kim, Altona Tufanoglu, Nolan R. Williams, Anna Wexler, David W. Oslin, Bruno Millet, Katherine W. Scangos, Bijan Pesaran, A. Eden Evins, R. Mark Richardson, Anna-Rose Childress, Casey H. Halpern: Localizing electrophysiologic cue-reactivity within the nucleus accumbens guides deep brain stimulation for opioid use disorder. BioRXiv Feb 2025.
Siddiqi SH, Chen L, Trapp NT, Bukhari-Parlakturk N, Taylor JJ, Boes AD, Brown JC, Barbour T, Camprodon JA, Fox MD, Kopell BH, MacMillan C, Fasano A, Fisher RS, Nahas Z, Revuelta GJ, Riva-Posse P, Rolston JD, Scangos K, Shafi MM, Smith AH, Wong J, Halpern CH, Mayberg HS, Williams NR.: Towards accredited clinical training in brain stimulation: Proceedings from the brain stimulation subspecialty summits. Brain Stimulation 18(2): 298-305, Feb 2025.