Welcome to Joeng Laboratory
Joeng laboratory is interested in signaling pathways regulating development and homeostasis of musculoskeletal system. We use moues genetic models to study the function of ER stress, mTORC1, and Wnt signaling in bone, cartilage and tendon. We are also interested in the involvement of these signaling pathways in injury repair. Recent studies showed that developmental signaling pathways are involved in injury repair of musculoskeletal tissue. We combines several surgery models with mouse genetic models to investigate the function of molecular signaling pathways in injury repair mechanism. Furthermore, we also studies the contribution of abnormal signaling pathways to the pathogenic mechanism of musculoskeletal diseases such as osteoarthritis, osteoporosis, and tendinopathy. We expect that our research programs will not only contribute to the understanding of musculoskeletal system, but also give insight into the advancement of regenerative medicine.