DirectoryInternal ResourcesReport a Problem

McKay Orthopaedic Research Laboratory

DirectoryInternal ResourcesReport a Problem
Navigate Gullbrand Laboratory
Gullbrand Laboratory

Brianna Orozco

Research Engineer
University of Pennsylvania

Hometown

Downey, California

Education

M.S.E. Candidate Bioengineering and Biomedical Engineering, University of Pennsylvania, 2025
B.S. Mechanical Engineering, California State University Fullerton, 2021

Areas of Special Interest

Brianna's areas of special interest include additive manufacturing, translational research, biomechanics, and musculoskeletal research. Outside of lab, she enjoys running, crocheting, and watching the occasional true crime documentary.

Awards

  • 2025 Orthopaedic Research Society Spine Section Travel Fellowship
  • Best Biomechanics Poster 2022 Penn Center for Musculoskeletal Disorders Symposium

Publications

  1. Ongini ED, Abdullah M, Engiles J, Orozco BS, Moehl A, Peredo A, Mahindroo S, Hilliard R, Schaer T, Mauck R, Smith H, Farshad M, Snedeker J, Gullbrand S. Annulus Fibrosus Repair via Interpenetration of a Non-Woven Scaffold Supports Tissue Integration and Prevents Re-Herniation. JOR Spine. 2025; 8(1): e70045. DOI: https://doi.org/10.1002/jsp2.70045
  2. Gullbrand SE, Kiapour A, Barrett C, Fainor M, Orozco BS, Hilliard R, Mauck RL, Hast MW, Schaer TP, Smith HE. Restoration of Physiologic Loading After Engineered Disc Implantation Mitigates Immobilization-Induced Facet Joint and Paraspinal Muscle Degeneration. Acta Biomaterialia. 2024. DOI: 10.1016/j.actbio.2024.12.014
  3. Gullbrand SE, Orozco BS, Fainor M, Meadows K, Hilliard R, Boyes M, Mahindroo S, Mauck RL, Elliott DM, Schaer TP, Smith HE. Intervertebral Disc Degeneration Instigates Vertebral Endplate Remodeling and Facet Joint Pathology in a Large Animal Model. European Cells and Materials. 2023; 47:125-141. DOI: 10.22203/eCM.v047a09
  4. Muir VG, Fainor M, Orozco BS, Hilliard RL, Boyes M, Smith HE, Mauck RL, Schaer TP, Burdick JA, Gullbrand SE. Injectable Radiopaque Hyaluronic Acid Granular Hydrogels for Intervertebral Disc Repair. Advanced Healthcare Materials. 2023. DOI: 10.1002/adhm.202303326
  5. Peredo AP, Gullbrand SE, Friday CS, Orozco BS, Dehghani B, Jenk AC, Bonnevie ED, Hilliard RL, Zlotnick HM, Dodge GR, Lee D, Engiles JB, Hast MW, Schaer TP, Smith HE, Mauck RL. Tension-Activated Nanofiber Patches Delivering an Anti-Inflammatory Drug Improve Repair in a Goat Intervertebral Disc Herniation Model. Science Translational Medicine. 2023; 15(722). DOI: 10.1126/scitranslmed.adf1690
  6. Orozco BS*, Fainor M*, Muir VG, Mahindroo S, Gupta S, Mauck RL, Burdick JA, Smith HE, Gullbrand SE. Mechanical Crosstalk Between the Intervertebral Disc, Facet Joints, and Vertebral Endplate Following Acute Disc Injury in a Rabbit Model. JOR Spine. 2023. DOI: 10.1002/jsp2.1287 

Conference Abstracts and Presentations

  1. Orozco BS & Gullbrand SE. Effects of Intervertebral Disc Health, Endplate Degeneration, and Solute Molecular Weight on Trans-endplate Diffusion. Proceedings of the Annual Meeting of the Orthopaedic Research Society 2025. February 7-11. Phoenix, AZ.
  2. Orozco BS, Fainor M, Muir VG, Schaer TP, Burdick JA, Gullbrand SE. Restoration of Degenerative Disc Function Contributes to Facet Cartilage Recovery in a Large Animal Model. Proceedings of the Annual Meeting of the Orthopaedic Research Society 2025. February 7-11. Phoenix, AZ.
  3. Ongini ED, Abdullah M, Engiles J, Orozco BS, Moehl A, Peredo A, Mahindroo S, Hilliard R, Schaer T, Mauck R, Smith H, Farshad M, Snedeker J, Gullbrand S. Annulus Repair via Interpenetrated Non-Woven Scaffold Supports Tissue Integration and Prevents Herniation. Proceedings of the Annual Meeting of the Orthopaedic Research Society 2025. February 7-11. Phoenix, AZ.
  4. Orozco BS & Gullbrand SE. Trans-Endplate Diffusion Across the Spectrum of Human Disc Degeneration. Proceedings of the Annual Meeting of the Orthopaedic Research Society 2024. Poster Presentation. February 2-6. Long Beach, CA.
  5. Gullbrand SE, Kiapour A, Hast M, Orozco BS, Fainor M, Godshall S, Hilliard R, Schaer T, Mauck RL, Smith HE. Mechanisms of Facet Degeneration Adjacent to Engineered Discs Implanted with Plate Fixation. Proceedings of the Annual Meeting of the Orthopaedic Research Society 2024. Podium Presentation. February 2-6. Long Beach, CA.
  6. Orozco BS, Fainor M, Muir V, Mahindroo S, Gupta S, Burdick J, Mauck RL, Smith HE, Gullbrand SE. Intervertebral Disc and Facet Crosstalk in a Rabbit Puncture Model of Disc Degeneration. Proceedings of the Annual Meeting of the Orthopaedic Research Society 2023. Podium Presentation. February 10-14. Dallas, TX.
  7. Gullbrand SE, Orozco BS, Fainor M, Hilliard RL, Schaer TP, Elliot DM, Mauck RL, Smith HE. Restoration of Physiologic Loading Improves Outcomes in Engineered Disc Implanted-Spinal Motion Segments. Proceedings of the Annual Meeting of the Orthopaedic Research Society 2023. Podium Presentation. February 10-14. Dallas, TX.
  8. Peredo AP, Gullbrand SE, Orozco BS, Hilliard R, Schaer TP, Smith HE, Mauck RL. Anti-Inflammatory Tension-Activated Repair Patches Promote Intervertebral Disc Repair After Herniation. Proceedings of the Annual Meeting of the Orthopaedic Research Society 2023. Podium Presentation. February 10-14. Dallas, TX.
  9. Orozco BS, Fainor M, Muir V, Mahindroo S, Gupta S, Burdick J, Mauck RL, Smith HE, Gullbrand SE. Intervertebral Disc and Facet Crosstalk in a Rabbit Puncture Model of Disc Degeneration. 2022 ORS PSRS 6th International Spine Research Symposium. Poster Presentation. November 6-10. Skytop, PA.
  10. Orozco BS, Ongini E, Moehl A, Peredo AP, Mahindroo S, Hillard R, Schaer TP, Mauck RL, Smith HE, Farshad M, Snedeker JG, Gullbrand SE. Repair of Intervertebral Disc Herniations with Surgical-FiberlockTM Technology. 2022 ORS PSRS 6th International Spine Research Symposium. Poster Presentation. November 6-10. Skytop, PA.
Back to Top