Soslowsky Laboratory

Jaime Santillan, PH.D

Post-doctoral Researcher
University of Pennsylvania


Lima, Perú


B.S. Physics, University of Puerto Rico, Rio Piedras campus

Ph.D. Chemical-Physics, University of Puerto Rico, Rio Piedras campus

Areas of Interest 

Biomechanics, Tissue regeneration, Polymeric Scaffold Materials, Electrospinning


  1. Santillán, J.; Dwomoh, E. A.; Rodríguez-Avilés, Y. G.; Bello, S. A.; Nicolau, E., Fabrication and Evaluation of Polycaprolactone Beads-on-String Membranes for Applications in Bone Tissue Regeneration. ACS Applied Bio Materials 2019.
  2. Vega-Figueroa, K.; Santillan, J.; Ortiz-Gomez, V.; Ortiz-Quiles, E. O.; Quinones-Colon, B. A.; Castilla-Casadiego, D. A.; Almodovar, J.; Bayro, M. J.; Rodriguez-Martinez, J. A.; Nicolau, E., Aptamer-Based Impedimetric Assay of Arsenite in Water: Interfacial Properties and Performance. ACS Omega 2018.
  3. Vega-Figueroa, K.; Santillán, J.; García, C.; González-Feliciano, J. A.; Bello, S. A.; Rodríguez, Y. G.; Ortiz-Quiles, E.; Nicolau, E., Assessing the Suitability of Cellulose-Nanodiamond Composite as a Multifunctional Biointerface Material for Bone Tissue Regeneration. ACS Biomaterials Science & Engineering 2017.
  4. Martínez Julca, M.; Rivera , I.; Santillan Mercado, J.; Sierra, H.; Perales-Pérez, O., Induced Structural Defects in Ti-Doped Zno and Its Two-Photon-Excitation. SPIE: 2016.

Selected Conference Abstracts and Presentations

  1. Santillan, J. Nicolau, E. Drug-loaded Biodegradable Scaffold for Controlled Release in Regenerative Medicine. ACS National Meeting, Orlando, FL, 2019
  2. Santillan, J.; Rodríguez, Y.; Nicolau, E. Applications of Nanotechnology in Bone Tissue Regeneration. ACS National Meeting, New Orleans, 2018
  3. Santillan, J.; Padilla, J.; Nicolau, E. Development of Engineered Bionanomaterials Based on Dispersed Nanodiamond into Self-Assembled Polystyrene-Block-Poly (Ethylene Oxide). ACS 253rd National Meeting, San Francisco, CA, 2017
  4. Dwomoh, E. A.; Santillan, J.; Rodríguez-Avilés, Y.; Bello, S. A.; Nicolau. E. Synthesis and Characterization of Polycaprolactone Membranes as Scaffolds for Bone Tissue Engineering. ACS 253rd National Meeting, San Francisco, CA, 2017
  5. Santillan, J.; Rodríguez-Avilés, Y.; Bello, S. A.; Nicolau. E.  Effect of Nanohydroxyapatite and Nanodiamond-coated Electrospun Cellulose Acetate Scaffolds on Osteoblast Morphology, Proliferation and Differentiation. Materials Research Society Fall Meeting. Boston, MA, 2016
  6. Santillan, J.; Siderius, D. Collection of Standard Reference Data for Gas Adsorption via Molecular Simulation and Literature Meta-analysis. SURF Student Colloquium – NIST, 2013

Book Chapters

  • Santillán-Mercado J.A., Rodríguez-Avilés Y.G., Bello S.A., González-Feliciano J.A., Nicolau E. (2017) Electrospun Cellulose and Nanocellulose Composites as a Biomaterial. In: Almodovar J. (eds) Electrospun Biomaterials and Related Technologies. Springer, Cham.

Jaime joined the McKay Orthopaedic Research Laboratory in January 2021 and currently is investigating new strategies to perform isolation and preserve collagen fibrils (roles of collagen XI and V) obtained from the mouse model before and after injury. He also studies the mechanical and morphological properties of collagen fibrils using AFM. When he is not in the Lab, Jaime enjoys playing soccer, cooking, and spending time with his family.

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