Chronobiology and Sleep Institute (CSI) Research Meetings, Seminars, and Retreats
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For over a decade, the Penn Sleep Clinical and Research groups have hosted an annual research retreat with the aim of promoting sleep medicine and circadian neurobiology research.
Since 2015, the Penn Chronobiology Program, now the Chronobiology and Sleep Institute (CSI), has partnered with the the the Penn Sleep Centers and Division of Sleep Medicine to host the joint Annual Research Retreat.
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2023 Annual CSI Research Retreat
Keynote Speaker: Catherine Dulac, PhD
Date: October 17, 2023
Location: Smilow Auditorium
Open to CSI and Penn affiliated researchers and clinicians, this annual event is a celebration for Penn sleep clinicians and researchers to share new abstracts, posters, and presentations or those from recent scientific meetings. Following the day long keynote presentations, sessions, and poster viewing, trainee awards are presented at the reception.
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THANK YOU FOR ATTENDING THE 2022 ANNUAL CSI RESEARCH RETREAT!
2022 CSI Research Retreat Trainee Awards- CONGRATULATIONS!
- Graduate Student Poster Awards: Jessica Schwarz (Sehgal lab) and Naureen Hameed (Barber lab)
- Postdoc Poster Awards: Amy Poe (Kayser lab) and Kun Zhu (Lazar lab)
- Undergraduate Student Poster Award: Akanksha Mathivanan (Barber lab)
Keynote: Luis de Lecea, PhD, Stanford Medicine, Department of Psychiatry and Behavioral Sciences
Keynote: Chiara Cirelli, MD, PhD, University of Wisconsin–Madison SOM, Department of Psychiatry
To celebrate the 25th anniversary of the CSCN, the 2016 retreat featured alumni talks on the Functions of Sleep, Circuits, OSA & Sleep Fragmentation, Genetics of Sleep, and Sleep Loss. There were also special remarks by Dean Larry Jameson, MD, PhD.
Functions of Sleep
- Dr. Matthew Kayser Sleep Deprivation Suppresses Aggression in Drosophila
- Dr. Sara Aton Sleep Dependent Memory Consolidation: Oscillation and Ensembles
- Dr. David Raizen Sleep Functions: Lessons from a Round Worm
Circuits
- Dr. Daniel Cavanaugh The Drosophila Circadian Clock Gates Sleep Timing through Interactions with Sleep-Promoting Neurons
- Dr. Mark Wu Sleep Drive is Encoded by Neural Plastic Changes in a Dedicated Circuit
OSA and Sleep Fragmentation
- Dr. Richard Schwab Important Insights into Sleep Apnea from Upper Airway Imaging
- Dr. Sigrid Veasey A Sleep Loss Locus for Alzheimer’s Disease
- Dr. Ulysses Magalang Sleep Apnea and Metabolic Dysfunction
- Dr. Richard Horner Mechanisms of REM Sleep
Genetics of Sleep
- Dr. Phil Gehrman Gene and Biomarkers of Insomnia
- Dr. Susan Harbison Sleep in Drosophila Melanogaster: Insights Gained from a Systems Genetics Approach
- Dr. Kyunghee Koh Sexually Dimorphic Regulation of Sleep in Drosophila
Sleep Loss
- Dr. Mathias Basner Identifying and Mitigating Sleep Restriction on Earth and in Space
- Dr. Hans Van Dongen Sleep Deprivation, Feedback Blunting and Dopaminergic Gene Polymorphisms
- Dr. Janet Mullington Effects of Repeated Sleep Restriction Challenge with Little Intervening Recovery Opportunity, on Autonomic and Inflammatory Parameters
- Dr. William Joiner Molecular and Neuroanatomical Control of Sleep Drive in Drosophila
KEYNOTE SPEAKER
William J. Schwartz, MD, Professor of Medicine, University of Massachusetts Medical School, Department of Neurology
SLEEP DISORDERS AND SLEEP LOSS
Wailuddin S. Khadeer “Use of Mobile Electronic Devices in Bed Associated with Sleep Duration, Insomnia, and Daytime Sleepiness”
Olga Tkachenko “The Impact of Recovery Sleep Opportunity on Neurobehavioral Measures Following Chronic Sleep Restriction”
Margaret C. Souders “Pilot Study of a Tailored Behavioral Intervention for Insomnia in Children with Autism Spectrum Disorder: Preliminary Results”
Christopher Cielo “Restless Legs Syndrome in Children with a History of Prematurity”
SLEEP, ENERGY AND METABOLISM
Stephen Wang “Effect of Weight-loss on Tongue Fat and Upper Airway Structures”
Arjun Sengupta “Estimation of Brain Response During Sleep from Serum Metabolome by NMR Spectroscopy”
Isaac J. Perron “Diet/Energy Balance Affect Sleep and Wakefulness Independent of Body Weight”
Sarah C. McLoughlin “Exercise Training Affects Metabolic and Locomotion Deficits of BMAL1 Prenatal Knockout Mice”
BASIC SLEEP AND CIRCADIAN SCIENCE
Nicholas F. Trojanowski “Distinct Mechanisms Underlie Two Types of Caenorhabditis Elegans Sleep”
David S. Garbe “Sex Differences in Drosophila Sleep Patterns”
Jennifer C. Tudor “Increasing Protein Synthesis in the Hippocampus Prevents Cognitive Impairments Caused by Sleep Deprivation”
ALL 2015 CSCN RETREAT ABSTRACTS
KEYNOTE SPEAKER
Michael Rosbash, PhD, Peter Gruber Endowed Chair in Neuroscience, Howard Hughes Medical Institute Investigator
SLEEP, HEALTH, AND ENVIRONMENTAL INFLUENCES
Michael A. Grandner “The Relationship between Sleep Duration and Cardiometabolic Risk Factors Depends on Race/Ethnicity and Whether Risk Factors Were Self-Reported or Objectively-Determined”
Jesse Schuschu “The Relationship Between Race/Ethnicity and Sleep Duration Depends on Geographic Location”
Mathias Basner “Inter-individual differences in the effects of aircraft noise on sleep fragmentation”
Andrea Spaeth “Baseline Slow-Wave Sleep Negatively Relates to Energy Balance Responses during Sleep Restriction in Healthy Adults”
Matthew Kayser “A Critical Period of Sleep for Development of Courtship Circuitry and Behavior in Drosophila”
ADVANCES IN SLEEP DISORDERS AND INTERVENTION RESEARCH
Sheila Garland “A Randomized Trial of Cognitive Behavior Therapy and Armodafinil to Treat Insomnia and Daytime Sleepiness in Cancer Survivors”
Carole Marcus “Long-Term Effects of Caffeine Therapy for Apnea of Prematurity on Sleep”
Renata Pellegrino “A Genome-wide Association Study of Apnea-Hypopnea Index in Children with Obstructive Breathing”
McKinstry-Wu “Inhibition of the Locus Coeruleus Impedes Emergence from Alkylphenol Hypnosis”
CIRCADIAN GENETICS
Sarah McLoughlin “Diurnal changes in autophagy and the role of the clock”
Heather Balance “Orchestrated Signal Transduction Unites Mammalian Circadian Metabolism Across Tissues”
Brian Altman “Rev-erbα Modulates Myc-Driven Cancer Cell Growth and Altered Metabolism”
Daniel Cavanaugh “Identification of a circadian output circuit for rest:activity rhythms in Drosophila”
Shailesh Kumar “An ecdysone-responsive nuclear receptor impacts circadian rhythms in Drosophila”
ALL 2014 CSCN RETREAT ABSTRACTS
KEYNOTE SPEAKER
Joseph Takahashi, PhD, Loyd B. Sands Distinguished Chair in Neuroscience,University of Texas Southwestern
SLEEP & NEURODEGENERATION
Jason Gerstner “Amyloid-beta Induced Sleep Fragmentation is Rescued by Fatty-acid Binding Proteins in Drosophila”
Marishka Brown “Aging Induced ER Stress Alters Sleep and Sleep Homeostasis”
Lama Chahine “Questionnaire-based Diagnosis of REM Sleep Behavior Disorder in Parkinson’s Disease”
OBSTRUCTIVE SLEEP APNEA, OBESITY & METABOLISM
Julio Chirinos “A Randomized Trial of Continuous Positive Airway Pressure Therapy, Weight Loss, orBoth for Obese Adults with Obstructive Sleep Apnea”
Victoria Pak “Obstructive Sleep Apnea, Obesity and Cellular Adhesion Molecules: Impact of2 Years of CPAP Treatment”
Beverly Shin “Respiratory-Related Dynamic Upper Airway Changes in Obese Apneics after Weight Loss”
NEUROANATOMY & FUNCTIONAL CONNECTIONS
Robbert Havekes “Sleep Deprivation Impairs Memory by Altering Cofilin and Actin Signaling”
Hilary McCarren “Stimulation of the α2a Adrenergic Receptor in the Ventrolateral Preoptic Area Promotes Arousal”
Anand Venkataraman “Bmal1fbrainKO Mice Exhibit Deficits in Learning and Memory Processes”
CIRCADIAN/HOMEOSTATIC SLEEP
Brian Altman “Oncogenic c- and N-Myc Disrupt Circadian Rhythm”
Mathias Basner “A Randomized Trial of a 3-hour Protected Nap Period in Medical Interns”
David Garbe “Cooperative Interaction between Phosphorylation Sites on PERIOD Maintains Circadian Period in Drosophila”
ALL 2013 CSCN RETREAT ABSTRACTS
KEYNOTE SPEAKER
Dr. Juliane Winkelmann – Max Planck Institute for Psychiatry
ALL 2010 CSCN RETREAT ABSTRACTS
KEYNOTE SPEAKER
Charles A. Czeisler, M.D.,Ph.D., Frank Baldino, Jr., Ph.D. Professor of Sleep Medicine, Harvard University