Ricardo Castillo, PhD DVM MSPH

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Assistant Professor of Biostatistics and Epidemiology
Scholar, Center for Global Health at University of Pennsylvania School of Medicine
Senior Scholar, Center for Clinical Epidemiology and Biostatistics at University of Pennsylvania School of Medicine
Department: Biostatistics and Epidemiology

Contact information
Department of Biostatistics, Epidemiology and Informatics
423 Guardian Dr.
Blockley Hall, Rm.715
Philadelphia, PA 19104
Office: 2157467333
Education:
BSc (Veterinary Medicine)
Universidad Nacional Mayor de San Marcos, 2006.
DVM (Veterinary Medicine)
Universidad Nacional Mayor de San Marcos, 2007.
PhD (Epidemiology)
Johns Hopkins Bloomberg School of Public Health, 2014.
MSPH (International Health)
Johns Hopkins Bloomberg School of Public Health, 2014.
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Description of Research Expertise

I study the eco-epidemiology of tropical diseases. My current research uses canine rabies as a model system to understand how the social and spatial features of urban areas influence the emergence and persistence of infectious diseases.

My most recent line of research focuses on urban vaccine-preventable outbreaks. I conduct cluster randomized trials to test optimized mass vaccination strategies. My methodological interests include spatial analysis, optimization of interventions to control infectious disease, and design of community-based studies.

I am a scholar of infectious disease epidemiology with a strong background in quantitative methods, zoonotic disease ecology, and the study of complex systems. I am committed to teaching and research in public health, infectious disease, and epidemiological methods. I am well-versed in designing and conducting observational and experimental community-based studies, as well as laboratory-based research. I have strong data management and analysis skills; and experience with a variety of data sources.

Selected Publications

Castillo-Neyra R, Gutierrez Zárate W, *Requena-Herrera MP, *Ortiz-Cam L, *Porras G, Manturano Lopez JM, Macedo Milla JF, **Cañari-Casaño JL, Bustos JA.: Hidden burden of surgical cystic echinococcosis in Arequipa, Peru: An unrecognized population at risk. MedRxiv. Aug 2025 Notes: *Student/predoctoral mentee; **Postdoctoral mentee.

*Porras G, *Diaz EW, *De la Puente M, Gavidia CM, Castillo-Neyra R.: Estimation of free-roaming dog populations using Google Street View: A Methodological Study. PLoS One. 20(7): e0305154, Aug 2025 Notes: *Student/predoctoral mentee.

De la Cruz-Saldana T, Bustos JA, *Requena-Herrera MP, Martinez-Merizalde N, *Ortiz-Cam L, Cáceres AL, Guzman C, Gavidia CM, Ugarte-Gil C, Castillo-Neyra R.: A scoping review on control strategies for Echinococcus granulosus sensu lato. IJID One Health. 8: 100078, Jul 2025 Notes: https://onehealth.ijidonline.org/article/S2949-9151(25)00026-5/fulltext; *Student/predoctoral mentee.

Castillo-Neyra R, *Ortiz-Cam L, **Cañari-Casaño JL, *Diaz EW, Tamayo LD, *Porras G, Recuenco SE, Paz-Soldan VA.: An implementation science framework to understand low coverage in mass dog rabies vaccination. PLoS Negl Trop Dis. 19(7): e0012869, Jul 2025 Notes: *Student/predoctoral mentee; **Postdoctoral mentee.

*Porras G, *Diaz EW, Leopardi V, **Xie S, *De la PuenteLeón M,*Ortiz-Cam L, Zegarra E, Monroy Y, Salazar R, Castillo-Neyra R.: A mixed methods evaluation of the foramen magnum and open skull methods for rabies Lyssavirus detection in dog brain samples. SSRN. Jun 2025 Notes: *Student/predoctoral mentee; **Postdoctoral mentee.

Tidman R, Larkins A, Auplish A, Benfield C, Cleaveland S, Fahrion AS, Leopardi V, Ghimire R, Morucci K, Sila S, Castillo-Neyra R, Okello A.: Evaluating cross-cutting opportunities for dog-mediated rabies control: A scoping review. Front Microbiol. 16: 1473929, Jun 2025.

*Diaz EW, Sila S, *Bellotti Raynor B, *De la Puente-León M, Levy MZ, Castillo-Neyra R.: Highly dynamic population of owned dogs and implications for zoonosis control. BioRxiv. Apr 2025 Notes: *Student/predoctoral mentee.

**Xie S, Shinnick J, *Diaz EW, Zegarra E, Monroy Y, Recuenco SE, Castillo-Neyra R.: Neighborhood socioeconomic status and dog-mediated rabies: Disparities in incidence and surveillance effort in a Latin American city. MedRxiv. Apr 2025 Notes: *Student/predoctoral mentee; **Postdoctoral mentee.

Salazar R, Brunker K, *Díaz EW, Zegarra E, Monroy Y, Baldarrago GN, Borrini-Mayorí K, *De la Puente-León M, Palmalux N, Nichols J, Kasaragod S, Levy MZ, Hampson K, Castillo-Neyra R.: Genomic characterization of a dog-mediated rabies outbreak in El Pedregal, Arequipa, Peru. PLoS Negl Trop Dis. 19(3), Mar 2025 Notes: *Student/predoctoral mentee.

*Bellotti BR, *Díaz EW, *De la Puente-León M, Rieders MT, Recuenco SE, Levy MZ, Castillo-Neyra R.: Challenging a paradigm: Staggered versus single-pulse mass dog vaccination strategy for rabies elimination. PLoS Comput Biol. 21(7): e1012780, Feb 2025 Notes: *Student/predoctoral mentee

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Last updated: 08/07/2025
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