Michael Silverman, MD, PhD

faculty photo
Assistant Professor of Pediatrics
Department: Pediatrics
Graduate Group Affiliations

Contact information
The Children's Hospital of Philadelphia
3615 Civic Center Blvd
Philadelphia, PA 19104
BS (Biology)
Cornell University, 1998.
MD, PhD (Medicine and Immunology)
University of Pennsylvania School of Medicine, 2007.
Permanent link
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Description of Clinical Expertise

Immunocompromised patients

Description of Research Expertise

Microbiome, Immunology, HLA, MHC, antibiotics, intestinal immune system, autoimmune (type I) diabetes, IgA deficiency, Graft-vs-host disease

Selected Publications

Mathew S. Kelly and Michael A. Silverman: Microbiome Implications in Transplantation and Oncology. Pediatric Transplant and Oncology Infectious Diseases. E, 1, 2020.

Tanca A, Palomba A, Fraumene C, Manghina V, Silverman M, Uzzau S.: Clostridial Butyrate Biosynthesis Enzymes Are Significantly Depleted in the Gut Microbiota of Nonobese Diabetic Mice. mSphere 3(5): doi: 10.1128, October 2018.

Dixit A, Alexandrescu S, Boyer D, Graf, EH, Vargas SO, Silverman M: Mycoplasma hominis empyema in an 18 year-old stem cell and lung transplant recipient: Case report and review of the literature. J Pediatric Infect Dis Soc 6(4): 173-176, November 2017.

Silverman M, Kua L, Tanco A, Pala M, Palomba A,Tanes C, Bittenger K, Uzzau S, Benoist C, and Mathis D: Protective major histocompatibility complex allele prevents type 1 diabetes by shaping the intestinal microbiota early in ontogeny. Proceedings of the National Academy of Sciences 114(36): 9671-9676, September 2017.

Alessandro Tanca, Valeria Manghina, Cristina Fraumene, Antonio Palomba, Marcello Abbondio, Massimo Deligios, Michael Silverman, Sergio Uzzau: Metaproteogenomics reveals taxonomic and functional changes between cecal and fecal microbiota in mouse. Frontiers in Microbiology 8(391): doi: 10.3389, March 2017 Notes: ecollection 2017.

Michael A Silverman, Liza Konnikova, Jeffrey Gerber: Impact of antibiotics on necrotizing enterocolitis and antibiotic-associated diarrhea. Gastroenterology Clinics of North America 46(1): 61-76, March 2017.

Silverman MA, Misasi J, Smole S, Feldman HA, Cohan AB, Santagata S, McManus M, Ahmed AA: Pediatric Eastern Equine encephalitis in Massachussettes and New Hampshire, 1970-2010. Emerging Infectious Diseases 19(2): 194-201, February 2013.

Kambayashi T, Larosa DF, Silverman MA, Koretzky GA: Cooperation of adapter molecules in proximal signaling cascades during allergic inflammation. Immunol Rev 232(1): 99-114, November 2009.

Michael Aaron Silverman: "SLP-76: Complex regulation of FcepsilonRI signaling in mast cells" Dissertations available from ProQuest. (eds.). January 2007 Notes: Paper AAI3260992. 

Olenchock BA, Guo R, Silverman MA, Wu JN, Carpenter JH, Koretzky GA, Zhong XP.: Impaired degranulation but enhanced cytokine production after FcepsilonRI stimulation of diacylglycerol kinase zeta-deficient mast cells. J Exp Med 205(5): 1471-80, May 2006.

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Last updated: 07/22/2019
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