Selected Publications

Tuteja S, O'Brien WJ, Ferraro JP, Damrauer SM, Itani KMF, Voight BF, Teerlink CC, Lynch JA, DuVall SL, Strebel T, Kim MJ, Wilson MA, Barrett TW; Million Veteran Program.: Drug-Gene Interactions and Clinical Outcomes After Vascular Surgery in the Million Veteran Program. JAMA Surg 160: 804-813, Jul 2025.

Tuteja S, Cayabyab MAS, Hoffecker G, Varughese LA, de Dieu Ndayishimiye J, Wittner VA, Wang X, Hatch R, Capozzi D, Harr M, Santani A, Hakonarson H, Watson D, Gabriel P, Doucette A, Massa R, Damjanov N, Reddy N, Oyer R, Teitelbaum UR.: Implementation of DPYD and UGT1A1 Testing in Patients With GI Cancer: A Prospective, Nonrandomized Clinical Trial. JCO Precis Oncol Page: e2500086. doi: 10.1200/PO-25-00086, August 2025.

Yang G, Alarcon C, Chanfreau C, Lee NH, Friedman P, Nutescu E, Tuck M, O'Brien T, Gong L, Klein TE, Chang KM, Tsao PS, Meltzer DO, Lynch JA; Million Veteran Program; Tuteja S, Perera MA.: Investigation of Genomic and Transcriptomic Risk Factors of Clopidogrel Response in African Americans. Clin Pharmacol Ther 117(5): 1313-1324, May 2025.

Chanfreau-Coffinier C, Friede KA, Plomondon ME, Lee KM, Lu Z, Dinatale T, DuVall SL, Vassy JL, Waldo SW, Cleator JH, Maddox TM, Rader DJ, Assimes TL, Damrauer SM, Tsao PS, Chang KM, Voora D, Lynch JA, Giri J; VA Million Veteran Program; Tuteja S.: CYP2C19 Polymorphisms and Clinical Outcomes Following Percutaneous Coronary Intervention in the Million Veteran Program. Clin Pharmacol Ther 118(4): 876-884, October 2025.

Ho TT, Smith DM, Aquilante CL, Cicali EJ, El Rouby N, Hertz DL, Imanirad I, Patel JN, Scott SA, Swain SM, Tuteja S, Hicks JK; Pharmacogenomics Global Research Network Publication Committee.: A Guide for Implementing DPYD Genotyping for Systemic Fluoropyrimidines into Clinical Practice. Clin Pharmacol Ther 117(5): 1194-1208, May 2025.

Stevenson JM, Smith DM, Tuteja S, Patel JN; Pharmacogenomics Global Research Network (PGRN) Publications Committee.: Navigating Pharmacogenomic Testing in Practice: Who to Test and When to Test. Clin Pharmacol Ther 118(3): 561-566, September 2025.

Hoffecker G, Mulugeta-Gordon L, Wittner V, Wang X, Gysler S, Deagostino-Kelly M, Tuteja S.: Feasibility of pharmacogenetic-guided selection of postoperative analgesics in gynecologic surgery patients: a prospective, randomized, pilot study. Pharmacogenet Genomics 35: 183-191, Aug 2025.

Pereira NL, Cresci S, Angiolillo DJ, Batchelor W, Capers Q 4th, Cavallari LH, Leifer D, Luzum JA, Roden DM, Stellos K, Turrise SL, Tuteja S; American Heart Association Professional/Public Education and Publications Committee of the Council on Genomic and Precision Medicine; Council on Arteriosclerosis, Thrombosis and Vascular Biology; Council on Cardiovascular and Stroke Nursing; Council on Clinical Cardiology; Council on Peripheral Vascular Disease; and Stroke Council.: CYP2C19 Genetic Testing for Oral P2Y12 Inhibitor Therapy: A Scientific Statement From the American Heart Association. Circulation 150: e129-e150, Aug 2024.

Oni-Orisan A, Tuteja S, Hoffecker G, Smith DM, Castrichini M, Crews KR, Murphy WA, Nguyen NHK, Huang Y, Lteif C, Friede KA, Tantisira K, Aminkeng F, Voora D, Cavallari LH, Whirl-Carrillo M, Duarte JD, Luzum JA; Pharmacogenomics Global Research Network (PGRN) Publications Committee.: An Introductory Tutorial on Cardiovascular Pharmacogenetics for Healthcare Providers. Clin Pharmacol Ther 114(2): 275-287, Aug 2023.

Tuteja S, Haynes K, Zayac C, Sprague JE, Bernhardt B, Pyeritz R: Community pharmacists' attitudes towards pharmacogenetic testing. Personalized Medicine 10(8): 793-800, Nov 2013.

Tuteja S, Rader DJ: High-density lipoproteins in the prevention of cardiovascular disease: changing the paradigm. Clinical Pharmacology and Therapeutics 96(1): 48-56, Jul 2014.

Cavallari LH, Beitelshees AL, Blake KV, Dressler LG, Duarte JD, Elsey A, Eichmeyer JN, Empey PE, Franciosi JP, Hicks JK, Holmes AM, Jeng L, Lee CR, Lima JJ, Limdi NA, Modlin J, Obeng AO, Petry N, Pratt VM, Skaar TC, Tuteja S, Voora D, Wagner M, Weitzel KW, Wilke RA, Peterson JF, Johnson JA: The implementing genomics in practice (IGNITE) pharmacogenetics interest group: An opportunity for building evidence with pharmacogenetics implementation. Clinical and Translational Science 10(3): 143-143, May 2017.

Empey Philip E, Stevenson James M, Tuteja Sony, Weitzel Kristin W, Angiolillo Dominick J, Beitelshees Amber L, Coons James C, Duarte Julio D, Franchi Francesco, Jeng Linda J B, Johnson Julie A, Kreutz Rolf P, Limdi Nita A, Maloney Kristin A, Owusu Obeng Aniwaa, Peterson Josh F, Petry Natasha, Pratt Victoria M, Rollini Fabiana, Scott Stuart A, Skaar Todd C, Vesely Mark R, Stouffer George A, Wilke Russell A, Cavallari Larisa H, Lee Craig R: Multi-site investigation of strategies for the implementation of CYP2C19 genotype-guided antiplatelet therapy. Clinical pharmacology and therapeutics 104(4): 664-674, Oct 2018.

Tuteja Sony, Wang Lu, Dunbar Richard L, Chen Jinbo, DerOhannessian Stephanie, Marcovina Santica M, Elam Marshall, Lader Ellis, Rader Daniel J: Genetic coding variants in the niacin receptor, hydroxyl-carboxylic acid receptor 2, and response to niacin therapy. Pharmacogenetics and genomics 27(8): 285-293, Aug 2017.

Chanfreau-Coffinier Catherine, Hull Leland E, Lynch Julie A, DuVall Scott L, Damrauer Scott M, Cunningham Francesca E, Voight Benjamin F, Matheny Michael E, Oslin David W, Icardi Michael S, Tuteja Sony: Projected Prevalence of Actionable Pharmacogenetic Variants and Level A Drugs Prescribed Among US Veterans Health Administration Pharmacy Users. JAMA network open 2(6): e195345, Jun 2019.

Dayoub Elias J, Nathan Ashwin S, Khatana Sameed Ahmed M, Seigerman Matthew, Tuteja Sony, Kobayashi Taisei, Kolansky Daniel M, Groeneveld Peter W, Giri Jay: Use of Prasugrel and Ticagrelor in Stable Ischemic Heart Disease After Percutaneous Coronary Intervention, 2009-2016. Circulation. Cardiovascular interventions 12(1): e007434, Jan 2019.

Varughese LA, Bhupathiraju M, Hoffecker G, Terek S, Harr M, Hakonarson H, Cambareri C, Marini J, Landgraf J, Chen J, Kanter G, Lau-Min KS, Massa RC, Damjanov N, Reddy NJ, Oyer RA, Teitelbaum UR, Tuteja S.: Implementing Pharmacogenetic Testing in Gastrointestinal Cancers (IMPACT-GI): Study Protocol for a Pragmatic Implementation Trial for Establishing DPYD and UGT1A1 Screening to Guide Chemotherapy Dosing. Front Oncol 12: 859846, Jul 2022.

Tuteja S, Yu Z, Wilson O, Chen HC, Wendt F, Chung CP, Shah SC, Hunt CM, Suzuki A, Chanfreau C, Gorman BR, Joseph J, Luoh SW, Napolioni V, Robinson-Cohen C, Tao R, Zhou J, Chang KM, Hung AM; VA Million Veteran Program COVID-19 Science Initiative.: Pharmacogenetic variants and risk of remdesivir-associated liver enzyme elevations in Million Veteran Program participants hospitalized with COVID-19. Clin Transl Sci 5(8): 1880-1886, Aug 2022.

Salloum RG, Bishop JR, Elchynski AL, Smith DM, Rowe E, Blake KV, Limdi NA, Aquilante CL, Bates J, Beitelshees AL, Cipriani A, Duong BQ, Empey PE, Formea CM, Hicks JK, Mroz P, Oslin D, Pasternak AL, Petry N, Ramsey LB, Schlichte A, Swain SM, Ward KM, Wiisanen K, Skaar TC, Van Driest SL, Cavallari LH, Tuteja S.: Best-worst scaling methodology to evaluate constructs of the Consolidated Framework for Implementation Research: application to the implementation of pharmacogenetic testing for antidepressant therapy. Implement Sci Commun 3(1): 52, May 2022.

Chanfreau-Coffinier C, Tuteja S, Hull LE, MacDonald S, Efimova O, Bates J, Voora D, Oslin DW, DuVall SL, Lynch JA.: Drug-drug-gene interaction risk among opioid users in the U.S. Department of Veterans Affairs. Pain 163(12): 2390-2397, Dec 2022.

Nathan AS, Geng Z, Eberly LA, Eneanya ND, Dayoub EJ, Khatana SAM, Kolansky DM, Kobayashi TJ, Tuteja S, Fanaroff AC, Giri J, Groeneveld PW.: Identifying Racial, Ethnic, and Socioeconomic Inequities in the Use of Novel P2Y12 Inhibitors After Percutaneous Coronary Intervention. J Invasive Cardiol 34(3): E171-E178, Mar 2022.

Tuteja S, Salloum RG, Elchynski AL, Smith DM, Rowe E, Blake KV, Limdi NA, Aquilante CL, Bates J, Beitelshees AL, Cipriani A, Duong BQ, Empey PE, Formea CM, Hicks JK, Mroz P, Oslin D, Pasternak AL, Petry N, Ramsey LB, Schlichte A, Swain SM, Ward KM, Wiisanen K, Skaar TC, Van Driest SL, Cavallari LH, Bishop JR; IGNITE Pharmacogenetics Working Group.: Multisite evaluation of institutional processes and implementation determinants for pharmacogenetic testing to guide antidepressant therapy. Clin Transl Sci 15(2): 371-383, Feb 2022.

Hicks JK, El Rouby N, Ong HH, Schildcrout JS, Ramsey LB, Shi Y, Anne Tang L, Aquilante CL, Beitelshees AL, Blake KV, Cimino JJ, Davis BH, Empey PE, Kao DP, Lemkin DL, Limdi NA, P Lipori G, Rosenman MB, Skaar TC, Teal E, Tuteja S, Wiley LK, Williams H, Winterstein AG, Van Driest SL, Cavallari LH, Peterson JF; IGNITE Pharmacogenetics Working Group.: Opportunity for Genotype-Guided Prescribing Among Adult Patients in 11 US Health Systems. Clin Pharmacol Ther 110(1): 179-188, Jul 2021.

Hoffecker G, Varughese LA, Bleznuck J, Landgraf J, Wollack C, Chen J, Ritchie MD, Nathanson KL, Tuteja S: Customizing the electronic health record for delivery of pharmacogenetics. Genetics in Medicine Open Mar 2023 Notes: Epub ahead of print doi.org/10.1016/j.gimo.2023.100779